Small molecule compounds targeting miRNAs for cancer therapy (Q26829982)

author name string

Paloma del C. Monroig

series ordinal

1

1 reference

Lu Chen

series ordinal

2

1 reference

Shuxing Zhang

series ordinal

3

1 reference

language of work or name

1 reference

January 2015

1 reference

Advanced Drug Delivery Reviews

published in

1 reference

volume

81

1 reference

page(s)

104-16

1 reference

Automated 3D structure composition for large RNAs

cites work

1 reference

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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A microRNA expression signature of human solid tumors defines cancer gene targets

7 April 2017

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7 April 2017

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The Microprocessor complex mediates the genesis of microRNAs

7 April 2017

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Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

7 April 2017

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The nuclear RNase III Drosha initiates microRNA processing

7 April 2017

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Oncomirs - microRNAs with a role in cancer

7 April 2017

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c-Myc-regulated microRNAs modulate E2F1 expression

7 April 2017

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7 April 2017

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MicroRNAs: genomics, biogenesis, mechanism, and function

7 April 2017

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Nuclear export of microRNA precursors

7 April 2017

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A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

7 April 2017

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The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

7 April 2017

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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

7 April 2017

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QSAR modeling: where have you been? Where are you going to?

7 April 2017

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The MC-Fold and MC-Sym pipeline infers RNA structure from sequence data

7 April 2017

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Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells

7 April 2017

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7 April 2017

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CompaRNA: a server for continuous benchmarking of automated methods for RNA secondary structure prediction

7 April 2017

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Treatment of HCV infection by targeting microRNA

7 April 2017

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Targeting cancer with small molecule kinase inhibitors

7 April 2017

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Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

7 April 2017

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7 April 2017

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Target Flexibility in RNA-Ligand Docking Modeled by Elastic Potential Grids

7 April 2017

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Evaluation of microRNA-10b prognostic significance in a prospective cohort of breast cancer patients.

28 September 2017

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A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein

28 September 2017

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Sequence-based design of bioactive small molecules that target precursor microRNAs

28 September 2017

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Targeting the production of oncogenic microRNAs with multimodal synthetic small molecules.

28 September 2017

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Up-regulation of miR-224 promotes cancer cell proliferation and invasion and predicts relapse of colorectal cancer

28 September 2017

1 reference

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Silencing of the miR-17~92 cluster family inhibits medulloblastoma progression

28 September 2017

1 reference

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miRNA and mRNA cancer signatures determined by analysis of expression levels in large cohorts of patients

28 September 2017

1 reference

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AC1MMYR2, an inhibitor of dicer-mediated biogenesis of Oncomir miR-21, reverses epithelial-mesenchymal transition and suppresses tumor growth and progression.

28 September 2017

1 reference

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Diversifying microRNA sequence and function

28 September 2017

1 reference

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The Role of microRNAs in the Tumorigenesis of Ovarian Cancer

28 September 2017

1 reference

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MicroRNA and Epigenetics: Diagnostic and Therapeutic Opportunities

28 September 2017

1 reference

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Targeting miR-21 for the therapy of pancreatic cancer

28 September 2017

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MiR-155 at the heart of oncogenic pathways

28 September 2017

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A molecular-beacon-based screen for small molecule inhibitors of miRNA maturation.

28 September 2017

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Discovering the first microRNA-targeted drug

28 September 2017

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Novel insights of structure-based modeling for RNA-targeted drug discovery

28 September 2017

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High-throughput luciferase reporter assay for small-molecule inhibitors of microRNA function.

28 September 2017

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The tuberculosis drug streptomycin as a potential cancer therapeutic: inhibition of miR-21 function by directly targeting its precursor.

28 September 2017

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aza-Flavanones as potent cross-species microRNA inhibitors that arrest cell cycle

28 September 2017

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Rich parameterization improves RNA structure prediction

28 September 2017

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Small molecule inhibition of RISC loading

28 September 2017

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MicroRNA regulation by RNA-binding proteins and its implications for cancer

28 September 2017

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28 September 2017

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Discovery of selective bioactive small molecules by targeting an RNA dynamic ensemble

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Identification of small molecules that suppress microRNA function and reverse tumorigenesis

28 September 2017

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Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma

28 September 2017

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miR-10b targets Tiam1: implications for Rac activation and carcinoma migration

28 September 2017

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Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model

28 September 2017

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Non-coding RNAs: identification of cancer-associated microRNAs by gene profiling

28 September 2017

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Small molecule modifiers of the microRNA and RNA interference pathway

28 September 2017

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Knowledge-based instantiation of full atomic detail into coarse-grain RNA 3D structural models

28 September 2017

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CENTROIDFOLD: a web server for RNA secondary structure prediction

28 September 2017

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MicroRNA and cancer--focus on apoptosis

28 September 2017

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MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis

28 September 2017

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Small-molecule inhibitors of microrna miR-21 function

28 September 2017

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A small molecule enhances RNA interference and promotes microRNA processing.

28 September 2017

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Docking to RNA via root-mean-square-deviation-driven energy minimization with flexible ligands and flexible targets

28 September 2017

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Bcl-2-targeted antisense therapy (Oblimersen sodium): towards clinical reality

28 September 2017

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DrugScoreRNA--knowledge-based scoring function to predict RNA-ligand interactions

28 September 2017

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miRNAs in cancer: approaches, aetiology, diagnostics and therapy

28 September 2017

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A fluorescence probe for assaying micro RNA maturation

28 September 2017

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A homogenous assay for micro RNA maturation

28 September 2017

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Validation of an empirical RNA-ligand scoring function for fast flexible docking using Ribodock

28 September 2017

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microRNAs: runts of the genome assert themselves

28 September 2017

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Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

28 September 2017

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Sequence requirements for micro RNA processing and function in human cells

28 September 2017

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CompaRNA: a server for continuous benchmarking of automated methods for RNA secondary structure prediction

28 September 2017

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Computational analysis and predictive modeling of small molecule modulators of microRNA

31 May 2018

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Towards 3D structure prediction of large RNA molecules: an integer programming framework to insert local 3D motifs in RNA secondary structure

31 May 2018

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Targeting microRNAs with small molecules: from dream to reality

31 May 2018

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microRNA-224 promotes cell proliferation and tumor growth in human colorectal cancer by repressing PHLPP1 and PHLPP2.

31 May 2018

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Xanthone derivatives as potential inhibitors of miRNA processing by human Dicer: targeting secondary structures of pre-miRNA by small molecules.

28 November 2018

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A local multiple alignment method for detection of non-coding RNA sequences

28 November 2018

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28 November 2018

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MicroRNA-21 promotes the cell proliferation, invasion and migration abilities in ovarian epithelial carcinomas through inhibiting the expression of PTEN protein

28 November 2018

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12 December 2020

SnapShot: MicroRNAs in Cancer

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Identifiers

DOI

1 reference

3435130

3435130

1 reference

1 reference

1 reference