Endothelial tip cells in ocular angiogenesis: potential target for anti-angiogenesis therapy (Q26865091)

retinal neovascularization

11 October 2019

2 references

14 October 2020

13 November 2020

1 reference

13 November 2020

1 reference

M. J. Siemerink

1

1 reference

I. Klaassen

series ordinal

2

1 reference

C. J. F. Van Noorden

series ordinal

3

1 reference

R. O. Schlingemann

series ordinal

4

1 reference

language of work or name

1 reference

February 2013

1 reference

Journal of Histochemistry and Cytochemistry

1 February 2013

6 references

25 April 2019

19 June 2019

25 June 2019

11 October 2019

14 October 2020

13 November 2020

7 references

25 April 2019

19 June 2019

25 June 2019

11 October 2019

14 October 2020

13 November 2020

61

1 reference

issue

2

1 reference

page(s)

101-15

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Creative Commons Attribution-NonCommercial 3.0 Unported

copyright license

6 references

25 April 2019

19 June 2019

25 June 2019

11 October 2019

14 October 2020

miR-221 is required for endothelial tip cell behaviors during vascular development

13 November 2020

cites work

1 reference

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miR-126 regulates angiogenic signaling and vascular integrity

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MicroRNAs regulate ocular neovascularization

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Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting

21 March 2017

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Molecular control of endothelial cell behaviour during blood vessel morphogenesis

21 March 2017

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Expression of the murine msr/apj receptor and its ligand apelin is upregulated during formation of the retinal vessels

21 March 2017

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Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

21 March 2017

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Retardation of retinal vascular development in apelin-deficient mice

21 March 2017

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Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

21 March 2017

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Filopodia: molecular architecture and cellular functions

21 March 2017

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Gamma-secretase inhibitor treatment promotes VEGF-A-driven blood vessel growth and vascular leakage but disrupts neovascular perfusion

21 March 2017

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VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis

21 March 2017

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Neuropilin-1 is required for endothelial tip cell guidance in the developing central nervous system

21 March 2017

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Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling

21 March 2017

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Extrinsic Notch ligand Delta-like 1 regulates tip cell selection and vascular branching morphogenesis

21 March 2017

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N-CAM exhibits a regulatory function in pathological angiogenesis in oxygen induced retinopathy

21 March 2017

1 reference

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HIF1A is essential for the development of the intermediate plexus of the retinal vasculature

21 March 2017

1 reference

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Cdc42 and RhoA have opposing roles in regulating membrane type 1-matrix metalloproteinase localization and matrix metalloproteinase-2 activation

21 March 2017

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Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

21 March 2017

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VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

7 April 2017

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Phosphorylation of threonine 1736 in the C-terminal tail of integrin β4 contributes to hemidesmosome disassembly

7 April 2017

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A shift in the balance of vascular endothelial growth factor and connective tissue growth factor by bevacizumab causes the angiofibrotic switch in proliferative diabetic retinopathy.

28 September 2017

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CD34 marks angiogenic tip cells in human vascular endothelial cell cultures

28 September 2017

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miR-27b controls venous specification and tip cell fate

28 September 2017

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From oxygen to erythropoietin: relevance of hypoxia for retinal development, health and disease

28 September 2017

1 reference

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New pathways and mechanisms regulating and responding to Delta-like ligand 4-Notch signalling in tumour angiogenesis

28 September 2017

1 reference

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How blood vessel networks are made and measured

28 September 2017

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Endothelial basement membrane limits tip cell formation by inducing Dll4/Notch signalling in vivo

28 September 2017

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VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling.

28 September 2017

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A human neutralizing antibody specific to Ang-2 inhibits ocular angiogenesis.

28 September 2017

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MicroRNA regulation in angiogenesis

28 September 2017

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Hyperoxia therapy of pre-proliferative ischemic retinopathy in a mouse model

28 September 2017

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Influence of Dll4 via HIF-1α-VEGF signaling on the angiogenesis of choroidal neovascularization under hypoxic conditions.

28 September 2017

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Flt1 acts as a negative regulator of tip cell formation and branching morphogenesis in the zebrafish embryo

28 September 2017

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Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice

28 September 2017

1 reference

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MicroRNAs in early diabetic retinopathy in streptozotocin-induced diabetic rats

28 September 2017

1 reference

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CXCL12 (SDF1alpha)-CXCR4/CXCR7 pathway inhibition: an emerging sensitizer for anticancer therapies?

28 September 2017

1 reference

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Diabetic retinopathy: targeting vasoregression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636692

Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636692

Identification and functional analysis of endothelial tip cell-enriched genes

28 September 2017

1 reference

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Targeting the ANGPT-TIE2 pathway in malignancy

28 September 2017

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New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes

28 September 2017

1 reference

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Animal models of choroidal and retinal neovascularization

28 September 2017

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The mouse retina as an angiogenesis model

28 September 2017

1 reference

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Axon guidance molecules in vascular patterning

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636692

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

28 September 2017

1 reference

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Endothelial cell adhesion to the extracellular matrix induces c-Src-dependent VEGFR-3 phosphorylation without the activation of the receptor intrinsic kinase activity

28 September 2017

1 reference

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Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction

28 September 2017

1 reference

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Ephrin-B2 regulates endothelial cell morphology and motility independently of Eph-receptor binding.

28 September 2017

1 reference

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Microarray analysis of retinal endothelial tip cells identifies CXCR4 as a mediator of tip cell morphology and branching

28 September 2017

1 reference

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Paracrine modulation of CXCR4 by IGF-1 and VEGF: implications for choroidal neovascularization

28 September 2017

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Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer

28 September 2017

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Treatment of retinal diseases with VEGF antagonists

28 September 2017

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Endothelial oxygen sensors regulate tumor vessel abnormalization by instructing phalanx endothelial cells.

28 September 2017

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The extracellular matrix of blood vessels

28 September 2017

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Soluble ephrin-B2 mediates apoptosis in retinal neovascularization and in endothelial cells

28 September 2017

1 reference

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Cellular and molecular mechanisms of vascular lumen formation

28 September 2017

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Attribution of vascular phenotypes of the murine Egfl7 locus to the microRNA miR-126.

28 September 2017

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Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors

28 September 2017

1 reference

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The angio-fibrotic switch of VEGF and CTGF in proliferative diabetic retinopathy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636692

Importance of pericytes and mechanisms of pericyte loss during diabetes retinopathy

28 September 2017

1 reference

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Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells

28 September 2017

1 reference

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Apelin is a potent activator of tumour neoangiogenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636692

Endothelial cell migration during angiogenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636692

The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636692

Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636692

Notch expression patterns in the retina: An eye on receptor-ligand distribution during angiogenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636692

Mechanisms of endothelial cell guidance and vascular patterning in the developing mouse retina

28 September 2017

1 reference

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Distinct modes of collagen type I proteolysis by matrix metalloproteinase (MMP) 2 and membrane type I MMP during the migration of a tip endothelial cell: insights from a computational model.

28 September 2017

1 reference

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Role of growth factors and the wound healing response in age-related macular degeneration

28 September 2017

1 reference

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Blood vessels and nerves: common signals, pathways and diseases

28 September 2017

1 reference

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Vascular endothelial growth factors and angiogenesis in eye disease

28 September 2017

1 reference

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Polarized vascular endothelial growth factor secretion by human retinal pigment epithelium and localization of vascular endothelial growth factor receptors on the inner choriocapillaris. Evidence for a trophic paracrine relation

28 September 2017

1 reference

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Altered vascular expression of EphrinB2 and EphB4 in a model of oxygen-induced retinopathy

28 September 2017

1 reference

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Differential TGF-{beta} signaling in retinal vascular cells: a role in diabetic retinopathy?

31 May 2018

1 reference

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Reduction in endothelial tip cell filopodia corresponds to reduced intravitreous but not intraretinal vascularization in a model of ROP.

31 May 2018

1 reference

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Pharmacologic and genetic manipulation of MMP-2 and -9 affects retinal neovascularization in rodent models of OIR.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636692

Early vascularization of the embryonic cerebral cortex: Golgi and electron microscopic studies

31 May 2018

1 reference

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Differential expression of markers for endothelial cells, pericytes, and basal lamina in the microvasculature of tumors and granulation tissue

31 May 2018

1 reference

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The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis

31 May 2018

1 reference

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Angiopoietin-2 plays an important role in retinal angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155412467635

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155412467635

Apelin is a crucial factor for hypoxia-induced retinal angiogenesis

21 January 2018

1 reference

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The formation of an angiogenic astrocyte template is regulated by the neuroretina in a HIF-1-dependent manner.

21 January 2018

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Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis

21 January 2018

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Potential role of the angiopoietin/tie2 system in ischemia-induced retinal neovascularization

21 January 2018

1 reference

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Apelin in plasma and vitreous and in fibrovascular retinal membranes of patients with proliferative diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155412467635

SDF-1/CXCR4 contributes to the activation of tip cells and microglia in retinal angiogenesis

21 January 2018

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VEGFR-3 in adult angiogenesis.

21 January 2018

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Soluble forms of EphrinB2 and EphB4 reduce retinal neovascularization in a model of proliferative retinopathy

21 January 2018

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Retinal vascular development is mediated by endothelial filopodia, a preexisting astrocytic template and specific R-cadherin adhesion.

21 January 2018

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Jagged gives endothelial tip cells an edge

28 November 2018

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12 December 2020

In vivo angiogenic phenotype of endothelial cells and pericytes induced by vascular endothelial growth factor-A

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12 December 2020

Leukocyte antigen CD34 is expressed by a subset of cultured endothelial cells and on endothelial abluminal microprocesses in the tumor stroma

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12 December 2020

Oxygen-induced retinopathy in the mouse

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12 December 2020

Effect of colchicine on remote phases of growing capillaries in the brain

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12 December 2020

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12 December 2020

Crosstalk between neovessels and mural cells directs the site-specific expression of MT1-MMP to endothelial tip cells

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12 December 2020

Effect of VEGF-A on expression of profibrotic growth factor and extracellular matrix genes in the retina

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12 December 2020

Therapeutic efficacy of a DNA vaccine targeting the endothelial tip cell antigen delta-like ligand 4 in mammary carcinoma

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12 December 2020

Laminin-Binding Integrins Induce Dll4 Expression and Notch Signaling in Endothelial Cells

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12 December 2020

MicroRNA-126 inhibits ischemia-induced retinal neovascularization via regulating angiogenic growth factors

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12 December 2020

Vascularization of the human fetal retina: roles of vasculogenesis and angiogenesis

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Identifiers

DOI

10.1369/0022155412467635

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

455431

OpenCitations bibliographic resource ID

455431

1 reference