Self-propagation of pathogenic protein aggregates in neurodegenerative diseases (Q26996441)

Crossref

language of work or name

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5 September 2013

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501

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issue

7465

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page(s)

45-51

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Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

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21 March 2017

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21 March 2017

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21 March 2017

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A Network Diffusion Model of Disease Progression in Dementia

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Brain homogenates from human tauopathies induce tau inclusions in mouse brain

28 September 2017

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28 September 2017

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28 September 2017

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Intrinsic connectivity network disruption in progressive supranuclear palsy

28 September 2017

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28 September 2017

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Prion-like spreading of pathological α-synuclein in brain

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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The case for intrinsically disordered proteins playing contributory roles in molecular recognition without a stable 3D structure

28 September 2017

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Protein disorder, prion propensities, and self-organizing macromolecular collectives.

28 September 2017

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Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy

28 September 2017

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Molecular structures of amyloid and prion fibrils: consensus versus controversy

28 September 2017

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Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons

28 September 2017

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Neuron-to-neuron transmission of α-synuclein fibrils through axonal transport

28 September 2017

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Cellular mechanisms of protein aggregate propagation

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Mutant p53 aggregates into prion-like amyloid oligomers and fibrils: implications for cancer.

28 September 2017

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Purified and synthetic Alzheimer's amyloid beta (Aβ) prions

28 September 2017

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Iatrogenic Creutzfeldt-Jakob disease, final assessment

28 September 2017

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Prion-like spread of protein aggregates in neurodegeneration

28 September 2017

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28 September 2017

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Trans-cellular propagation of Tau aggregation by fibrillar species

28 September 2017

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Predicting regional neurodegeneration from the healthy brain functional connectome

28 September 2017

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The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease.

28 September 2017

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The amyloid state of proteins in human diseases

28 September 2017

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The molecular basis of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum

28 September 2017

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Review: Creutzfeldt-Jakob disease: prion protein type, disease phenotype and agent strain.

28 September 2017

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A molecular history of the amyloidoses

28 September 2017

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The transthyretin amyloidoses: from delineating the molecular mechanism of aggregation linked to pathology to a regulatory-agency-approved drug

28 September 2017

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The presence of Aβ seeds, and not age per se, is critical to the initiation of Aβ deposition in the brain

28 September 2017

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The seeds of neurodegeneration: prion-like spreading in ALS

28 September 2017

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Exogenous seeding of cerebral β-amyloid deposition in βAPP-transgenic rats

28 September 2017

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Soluble Aβ seeds are potent inducers of cerebral β-amyloid deposition

28 September 2017

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Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death

28 September 2017

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Intermolecular transmission of superoxide dismutase 1 misfolding in living cells

28 September 2017

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Resolving controversies on the path to Alzheimer's therapeutics

28 September 2017

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Nanomechanics of functional and pathological amyloid materials.

28 September 2017

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Neuronal activity regulates the regional vulnerability to amyloid-β deposition

28 September 2017

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Alzheimer's disease: the challenge of the second century

28 September 2017

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Amyloid structure: conformational diversity and consequences

28 September 2017

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28 September 2017

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Brain networks in Huntington disease

28 September 2017

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Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions

28 September 2017

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Abeta42 neurotoxicity is mediated by ongoing nucleated polymerization process rather than by discrete Abeta42 species

28 September 2017

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Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis

28 September 2017

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Biology of amyloid: structure, function, and regulation

28 September 2017

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Prion-like aggregates: infectious agents in human disease

28 September 2017

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Molecular pathology of human prion disease

28 September 2017

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Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process

28 September 2017

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The transcellular spread of cytosolic amyloids, prions, and prionoids

28 September 2017

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Prions: protein aggregation and infectious diseases

28 September 2017

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ALS motor phenotype heterogeneity, focality, and spread: deconstructing motor neuron degeneration

28 September 2017

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Functional amyloids as natural storage of peptide hormones in pituitary secretory granules

28 September 2017

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Getting a grip on prions: oligomers, amyloids, and pathological membrane interactions

28 September 2017

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Molecular polymorphism of Abeta in Alzheimer's disease

28 September 2017

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Fecal transmission of AA amyloidosis in the cheetah contributes to high incidence of disease.

28 September 2017

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28 September 2017

Chronic wasting disease

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Kuru in the 21st century--an acquired human prion disease with very long incubation periods

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Transmission of amyloidosis in offspring of mice with AApoAII amyloidosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

The most infectious prion protein particles.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Synthetic mammalian prions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Evidence for the experimental transmission of cerebral beta-amyloidosis to primates

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Spontaneous generation of infectious nucleating amyloids in the transmissible and nontransmissible cerebral amyloidoses

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Prion protein transgenes and the neuropathology in prion diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Axonal and transneuronal transport in the transmission of neurological disease: potential role in system degenerations, including Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Spike bursts increase amyloid-β 40/42 ratio by inducing a presenilin-1 conformational change

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Amyloid-β forms fibrils by nucleated conformational conversion of oligomers

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Cross-seeding and cross-competition in mouse apolipoprotein A-II amyloid fibrils and protein A amyloid fibrils

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

A review of the epidemiology of scrapie in sheep.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

100 years of Lewy pathology.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Amyloid fibril protein nomenclature: 2012 recommendations from the Nomenclature Committee of the International Society of Amyloidosis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Spreading of neurodegenerative pathology via neuron-to-neuron transmission of β-amyloid.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

De novo induction of amyloid-β deposition in vivo.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Prion-like acceleration of a synucleinopathy in a transgenic mouse model.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Gain of function of mutant p53 by coaggregation with multiple tumor suppressors

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

The physical basis of how prion conformations determine strain phenotypes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Phases of A beta-deposition in the human brain and its relevance for the development of AD.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Evidence for seeding of beta -amyloid by intracerebral infusion of Alzheimer brain extracts in beta -amyloid precursor protein-transgenic mice.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963807

Transmission of mouse senile amyloidosis

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/24005412

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The benefits and limitations of animal models for translational research in neurodegenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/24005412

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE12481

1 reference

Dimensions Publication ID

320466

1047908684

0 references

320466

1 reference

1 reference

1 reference