Therapeutic targets in the ASK1-dependent stress signaling pathways (Q26999030)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23060232%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

3 references

26 August 2020

20 October 2020

13 November 2020

Therapeutic targets in the ASK1-dependent stress signaling pathways (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23060232%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

main subject

physiological phenomenon

1 reference

20 August 2019

1 reference

28 September 2019

1 reference

20 November 2019

1 reference

26 August 2020

1 reference

20 October 2020

1 reference

13 November 2020

3

1 reference

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10 March 2020

Hidenori Ichijō

series ordinal

4

1 reference

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10 March 2020

author name string

Ryoichi Hayakawa

series ordinal

1

1 reference

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10 March 2020

Teruyuki Hayakawa

series ordinal

2

1 reference

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10 March 2020

language of work or name

1 reference

1 January 2012

1 reference

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Proceedings of the Japan Academy, Series B

10 March 2020

published in

8 references

25 June 2019

20 August 2019

28 September 2019

20 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23060232%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

26 August 2020

13 November 2020

88

2 references

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10 March 2020

issue

8

2 references

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10 March 2020

page(s)

434-453

1 reference

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Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1

10 March 2020

cites work

1 reference

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Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death

21 March 2017

1 reference

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Interaction of apoptosis signal-regulating kinase 1 with isoforms of 14-3-3 proteins

21 March 2017

1 reference

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ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

21 March 2017

1 reference

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Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer

21 March 2017

1 reference

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HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell

21 March 2017

1 reference

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Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

21 March 2017

1 reference

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Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins

21 March 2017

1 reference

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Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx

21 March 2017

1 reference

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Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

21 March 2017

1 reference

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Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

21 March 2017

1 reference

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Structural and Functional Characterization of the Human Protein Kinase ASK1

21 March 2017

1 reference

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Alzheimer's disease: genes, proteins, and therapy

21 March 2017

1 reference

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Apoptosis signal-regulating kinase 1 (ASK1) induces neuronal differentiation and survival of PC12 cells

21 March 2017

1 reference

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Astrocytes in multiple sclerosis: a product of their environment

21 March 2017

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Novel mechanism and role of angiotensin II induced vascular endothelial injury in hypertensive diastolic heart failure

21 March 2017

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Tumor necrosis factor-alpha and apoptosis signal-regulating kinase 1 control reactive oxygen species release, mitochondrial autophagy, and c-Jun N-terminal kinase/p38 phosphorylation during necrotizing enterocolitis

21 March 2017

1 reference

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Regulation of cardiac hypertrophy by intracellular signalling pathways

7 April 2017

1 reference

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Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing

7 April 2017

1 reference

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An overview of nonalcoholic steatohepatitis: past, present and future directions

28 September 2017

1 reference

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Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer

28 September 2017

1 reference

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Angiotensin II receptors and drug discovery in cardiovascular disease

28 September 2017

1 reference

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Identification of novel ASK1 inhibitors using virtual screening

28 September 2017

1 reference

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Regulation of the severity of neuroinflammation and demyelination by TLR-ASK1-p38 pathway

28 September 2017

1 reference

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Flow shear stress and atherosclerosis: a matter of site specificity

28 September 2017

1 reference

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Apoptosis signaling kinases: from stress response to health outcomes

28 September 2017

1 reference

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Alzheimer disease: update on basic mechanisms.

28 September 2017

1 reference

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The ASK1-Signalosome regulates p38 MAPK activity in response to levels of endogenous oxidative stress in the Klotho mouse models of aging

28 September 2017

1 reference

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Myeloid cell death associated with Toll-like receptor 7/8-mediated inflammatory response. Implication of ASK1, HIF-1 alpha, IL-1 beta and TNF-alpha

28 September 2017

1 reference

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Knockdown of apoptosis signal-regulating kinase 1 modulates basal glycogen synthase kinase-3β kinase activity and regulates cell migration.

28 September 2017

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Inflammation, demyelination, and degeneration - recent insights from MS pathology.

28 September 2017

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Mouse models for multiple sclerosis: historical facts and future implications

28 September 2017

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Japanese encephalitis virus down-regulates thioredoxin and induces ROS-mediated ASK1-ERK/p38 MAPK activation in human promonocyte cells

28 September 2017

1 reference

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DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex.

28 September 2017

1 reference

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Neuroprotective effect of overexpression of thioredoxin on photoreceptor degeneration in Tubby mice

28 September 2017

1 reference

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Parkinson's disease: oxidative stress and therapeutic approaches.

28 September 2017

1 reference

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DJ-1 modulates the p38 mitogen-activated protein kinase pathway through physical interaction with apoptosis signal-regulating kinase 1.

28 September 2017

1 reference

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Activation of apoptosis signal-regulating kinase 1 is a key factor in paraquat-induced cell death: modulation by the Nrf2/Trx axis.

28 September 2017

1 reference

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Variants in ASK1 are associated with skeletal muscle ASK1 expression, in vivo insulin resistance, and type 2 diabetes in Pima Indians

28 September 2017

1 reference

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Kinase inhibitors: a new approach to rheumatoid arthritis treatment

28 September 2017

1 reference

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Dermal fibroblasts from long-lived Ames dwarf mice maintain their in vivo resistance to mitochondrial generated reactive oxygen species (ROS)

28 September 2017

1 reference

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Oxidative stress-enhanced SUMOylation and aggregation of ataxin-1: Implication of JNK pathway

28 September 2017

1 reference

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Ubiquitin-like sequence in ASK1 plays critical roles in the recognition and stabilization by USP9X and oxidative stress-induced cell death.

28 September 2017

1 reference

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"Go upstream, young man": lessons learned from the p38 saga

28 September 2017

1 reference

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Intracellular shuttling and mitochondrial function of thioredoxin-interacting protein

28 September 2017

1 reference

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c-Jun N-terminal kinase (JNK) signaling: recent advances and challenges.

28 September 2017

1 reference

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A TNF- and c-Cbl-dependent FLIP(S)-degradation pathway and its function in Mycobacterium tuberculosis-induced macrophage apoptosis

28 September 2017

1 reference

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Notch activation induces Akt signaling via an autocrine loop to prevent apoptosis in breast epithelial cells.

28 September 2017

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Oxidizable residues mediating protein stability and cytoprotective interaction of DJ-1 with apoptosis signal-regulating kinase 1

28 September 2017

1 reference

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Hepatitis C virus core protein triggers hepatic angiogenesis by a mechanism including multiple pathways

28 September 2017

1 reference

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ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis.

28 September 2017

1 reference

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Implication of the JNK pathway in a rat model of Huntington's disease

28 September 2017

1 reference

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Role of apoptosis-regulating signal kinase 1 in innate immune responses by Mycobacterium bovis bacillus Calmette-Guérin

28 September 2017

1 reference

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High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo

28 September 2017

1 reference

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Role of angiotensin II AT1 receptor activation in cardiovascular diseases

28 September 2017

1 reference

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ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1.

28 September 2017

1 reference

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ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease.

28 September 2017

1 reference

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Mitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases

28 September 2017

1 reference

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MAPKs and their relevance to arthritis and inflammation

28 September 2017

1 reference

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Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis

28 September 2017

1 reference

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ASK1-p38 MAPK-p47phox activation is essential for inflammatory responses during tuberculosis via TLR2-ROS signalling

28 September 2017

1 reference

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The mitochondrial superoxide/thioredoxin-2/Ask1 signaling pathway is critically involved in troglitazone-induced cell injury to human hepatocytes

28 September 2017

1 reference

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Inhibition of glial cell activation ameliorates the severity of experimental autoimmune encephalomyelitis.

28 September 2017

1 reference

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Apoptosis signal-regulating kinase 1 in stress and immune response

28 September 2017

1 reference

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Oxidative stress and cardiac repair/remodeling following infarction

28 September 2017

1 reference

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Interaction of ASK1 and the beta-amyloid precursor protein in a stress-signaling complex

28 September 2017

1 reference

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Nitrative thioredoxin inactivation as a cause of enhanced myocardial ischemia/reperfusion injury in the aging heart

28 September 2017

1 reference

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Novel strategies for inhibition of the p38 MAPK pathway.

28 September 2017

1 reference

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TNF-alpha suppresses prolyl-4-hydroxylase alpha1 expression via the ASK1-JNK-NonO pathway

28 September 2017

1 reference

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The 14-3-3tau phosphoserine-binding protein is required for cardiomyocyte survival

28 September 2017

1 reference

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Induction of heat shock response protects the heart against atrial fibrillation.

28 September 2017

1 reference

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Role of MAPKs in development and differentiation: lessons from knockout mice.

28 September 2017

1 reference

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Targeting signal transduction as a strategy to treat inflammatory diseases.

28 September 2017

1 reference

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Impact of mitochondrial reactive oxygen species and apoptosis signal-regulating kinase 1 on insulin signaling

28 September 2017

1 reference

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New approaches to the treatment of inflammatory disorders small molecule inhibitors of p38 MAP kinase.

28 September 2017

1 reference

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MAP kinase p38 inhibitors: clinical results and an intimate look at their interactions with p38alpha protein

28 September 2017

1 reference

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Enhanced TNF-alpha-induced apoptosis in Fanconi anemia type C-deficient cells is dependent on apoptosis signal-regulating kinase 1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Apoptosis signal-regulating kinase 1 in leukotriene D(4)-induced activator protein-1 activation in airway smooth muscle cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.

28 September 2017

1 reference

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Tau phosphorylation in Alzheimer's disease: potential involvement of an APP-MAP kinase complex.

28 September 2017

1 reference

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Amyloid beta induces neuronal cell death through ROS-mediated ASK1 activation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Involvement of ASK1 in Ca2+-induced p38 MAP kinase activation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling

28 September 2017

1 reference

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Defining the involvement of p38alpha MAPK in the production of anti- and proinflammatory cytokines using an SB 203580-resistant form of the kinase

28 September 2017

1 reference

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The CaMKII UNC-43 activates the MAPKKK NSY-1 to execute a lateral signaling decision required for asymmetric olfactory neuron fates

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Apoptosis signal-regulating kinase 1 (ASK1) is an intracellular inducer of keratinocyte differentiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Inhibition of p38 MAP kinase as a therapeutic strategy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Role of apoptosis signal-regulating kinase in regulation of the c-Jun N-terminal kinase pathway and apoptosis in sympathetic neurons

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Expression of MCP-1 by reactive astrocytes in demyelinating multiple sclerosis lesions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Mechanisms of neuronal degeneration in Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Critical role for apoptosis signal-regulating kinase 1 in the development of inflammatory K/BxN serum-induced arthritis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Increased expression of IRE1alpha and stress-related signal transduction proteins in ischemia-reperfusion injured retina

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Deletion of apoptosis signal-regulating kinase 1 attenuates acetaminophen-induced liver injury by inhibiting c-Jun N-terminal kinase activation

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

ASK1 regulates influenza virus infection-induced apoptotic cell death

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Hydrogen peroxide mediates amyloid beta protein toxicity

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Tumor necrosis factor-alpha accelerates apoptosis of steatotic hepatocytes from a murine model of non-alcoholic fatty liver disease.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase.

19 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Involvement of IRE1α signaling in the hippocampus in patients with mesial temporal lobe epilepsy.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Heat shock transcription factor-1 inhibits H2O2-induced apoptosis via down-regulation of reactive oxygen species in cardiac myocytes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates lipopolysaccharide-induced tissue factor expression in pulmonary microvasculature.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

ASK1 deficiency attenuates neural cell death in GLAST-deficient mice, a model of normal tension glaucoma

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Apoptosis Signal-Regulating Kinase 1 Regulates Colitis and Colitis-Associated Tumorigenesis by the Innate Immune Responses

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Inhibition of apoptosis signal-regulating kinase 1 reduces endoplasmic reticulum stress and nuclear huntingtin fragments in a mouse model of Huntington disease

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Critical role of apoptosis signal-regulating kinase 1 in aldosterone/salt-induced cardiac inflammation and fibrosis.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Redox activated MAP kinase death signaling cascade initiated by ASK1 is not activated in female mice following MPTP: novel mechanism of neuroprotection.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Efficacy, pharmacodynamics, and safety of VX-702, a novel p38 MAPK inhibitor, in rheumatoid arthritis: results of two randomized, double-blind, placebo-controlled clinical studies.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Efficacy and safety of pamapimod in patients with active rheumatoid arthritis receiving stable methotrexate therapy

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Blockade of oxidized LDL-triggered endothelial apoptosis by quercetin and rutin through differential signaling pathways involving JAK2.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Evaluation of the efficacy and safety of pamapimod, a p38 MAP kinase inhibitor, in a double-blind, methotrexate-controlled study of patients with active rheumatoid arthritis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Ras-driven proliferation and apoptosis signaling during rat liver carcinogenesis is under genetic control.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Olmesartan prevents cardiovascular injury and hepatic steatosis in obesity and diabetes, accompanied by apoptosis signal regulating kinase-1 inhibition

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

The K/BxN arthritis model

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Role of apoptosis signal-regulating kinase 1 in complement-mediated glomerular epithelial cell injury

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Induction of apoptosis signal-regulating kinase 1 and oxidative stress mediate age-dependent vulnerability to 3-nitropropionic acid in the mouse striatum

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Important role of apoptosis signal-regulating kinase 1 in ischemic acute kidney injury

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

The potential role of glutamate transporters in the pathogenesis of normal tension glaucoma

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death-associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinson's disease: protection by alpha-lipoic acid

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Inhibition of p38 mitogen activated protein kinase activation and mutant SOD1G93A-induced motor neuron death

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Apoptosis signal-regulating kinase 1 is involved not only in apoptosis but also in non-apoptotic cardiomyocyte death.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Activation of the stress-activated MAP kinase, p38, but not JNK in cortical motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in transgenic mice

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Oxidant hypersensitivity of Fanconi anemia type C-deficient cells is dependent on a redox-regulated apoptotic pathway

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Apoptosis signal-regulating kinase 1 plays a pivotal role in angiotensin II-induced cardiac hypertrophy and remodeling.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Essential role of E2-25K/Hip-2 in mediating amyloid-beta neurotoxicity

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates nitric oxide-induced activator protein-1 activation in human bronchial epithelial cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Reaper-mediated inhibition of DIAP1-induced DTRAF1 degradation results in activation of JNK in Drosophila

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Execution of Apoptosis Signal-regulating Kinase 1 (ASK1)-induced Apoptosis by the Mitochondria-dependent Caspase Activation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Co-expression of Fas and Fas-ligand on the surface of influenza virus-infected cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491083

Biphasic activation of apoptosis signal-regulating kinase 1-stress-activated protein kinase 1-c-Jun N-terminal protein kinase pathway is selectively mediated by Ca2+-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors involving

28 November 2018

1 reference

12 December 2020

K252a prevents nigral dopaminergic cell death induced by 6-hydroxydopamine through inhibition of both mixed-lineage kinase 3/c-Jun NH2-terminal kinase 3 (JNK3) and apoptosis-inducing kinase 1/JNK3 signaling pathways

1 reference

12 December 2020

Oral p38 mitogen-activated protein kinase inhibition with BIRB 796 for active Crohn's disease: a randomized, double-blind, placebo-controlled trial

1 reference

12 December 2020

Amyotrophic lateral sclerosis

1 reference

12 December 2020

Heat shock transcription factor 1 protects cardiomyocytes from ischemia/reperfusion injury

1 reference

12 December 2020

Expression of apoptosis signal-regulating kinase 1 in mouse spinal cord under chronic mechanical compression: possible involvement of the stress-activated mitogen-activated protein kinase pathways in spinal cord cell apoptosis

1 reference

12 December 2020

Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as inhibitors of apoptosis signal-regulating kinase 1 (ASK1)

1 reference

12 December 2020

Low p38 MAPK and JNK activation in cultured hepatocytes of DRH rats; a strain highly resistant to hepatocarcinogenesis

1 reference

12 December 2020

Activation of ASK1 during reperfusion of ischemic spinal cord

1 reference

12 December 2020

Chemokine expression by astrocytes plays a role in microglia/macrophage activation and subsequent neurodegeneration in secondary progressive multiple sclerosis

1 reference

12 December 2020

[Identification of low-molecular inhibitors of proteinase ASK1]

1 reference

12 December 2020

Nonalcoholic fatty liver disease

1 reference

12 December 2020

Activation of programmed cell death markers in ventral horn motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in a transgenic mouse model

1 reference

12 December 2020

Identifiers

DOI

10.2183/PJAB.88.434

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23060232%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23060232%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

23060232

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23060232%20AND%20SRC:MED&resulttype=core&format=json