Heterogeneity in immune responses: from populations to single cells (Q27013828)

Crossref

language of work or name

1 reference

May 2014

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1 reference

35

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issue

5

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page(s)

219-29

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Innate and adaptive immune cells in the tumor microenvironment

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21 March 2017

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Using gene expression noise to understand gene regulation

21 March 2017

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Single-cell dissection of transcriptional heterogeneity in human colon tumors

21 March 2017

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Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum

21 March 2017

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Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

21 March 2017

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Nature, nurture, or chance: stochastic gene expression and its consequences

21 March 2017

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Stochastic mRNA synthesis in mammalian cells

21 March 2017

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Th17 and regulatory T cells in mediating and restraining inflammation

21 March 2017

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Type, density, and location of immune cells within human colorectal tumors predict clinical outcome

21 March 2017

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Stochastic gene expression in a single cell

21 March 2017

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Adoptive immunotherapy for cancer: harnessing the T cell response

21 March 2017

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Multi-scale stochastic simulation of diffusion-coupled agents and its application to cell culture simulation

21 March 2017

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Global quantification of mammalian gene expression control

21 March 2017

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Regulatory T cells exert checks and balances on self tolerance and autoimmunity

21 March 2017

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Timing cellular decision making under noise via cell-cell communication

21 March 2017

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Tumour evolution inferred by single-cell sequencing

21 March 2017

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FOXP3+ regulatory T cells in the human immune system

21 March 2017

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Single-cell Hi-C reveals cell-to-cell variability in chromosome structure

7 April 2017

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Monocyte and macrophage heterogeneity

7 April 2017

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Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells

7 April 2017

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Functional roles for noise in genetic circuits

7 April 2017

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A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

7 April 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Differentiation of effector CD4 T cell populations (*)

7 April 2017

1 reference

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BRAF mutation predicts sensitivity to MEK inhibition

7 April 2017

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Noise in eukaryotic gene expression

7 April 2017

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Intrinsic and extrinsic contributions to stochasticity in gene expression

7 April 2017

1 reference

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Probabilistic splicing of Dscam1 establishes identity at the level of single neurons.

7 April 2017

1 reference

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Quantitative assessment of single-cell RNA-sequencing methods.

28 September 2017

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B-cell receptor signaling as a driver of lymphoma development and evolution

28 September 2017

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Smart-seq2 for sensitive full-length transcriptome profiling in single cells.

28 September 2017

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Single-cell DNA-methylation analysis reveals epigenetic chimerism in preimplantation embryos

28 September 2017

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The role of lung dendritic cell subsets in immunity to respiratory viruses

28 September 2017

1 reference

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Stochastic cytokine expression induces mixed T helper cell States

28 September 2017

1 reference

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Visualization of multivalent histone modification in a single cell reveals highly concerted epigenetic changes on differentiation of embryonic stem cells

28 September 2017

1 reference

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viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection.

28 September 2017

1 reference

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Immunological Genome Project and systems immunology.

28 September 2017

1 reference

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Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Bcl6 expressing follicular helper CD4 T cells are fate committed early and have the capacity to form memory

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Dynamic regulatory network controlling TH17 cell differentiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Evolution and impact of subclonal mutations in chronic lymphocytic leukemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Detection of histone modifications at specific gene loci in single cells in histological sections

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

CEL-Seq: single-cell RNA-Seq by multiplexed linear amplification

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Protocadherins mediate dendritic self-avoidance in the mammalian nervous system

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Genome-wide single-cell analysis of recombination activity and de novo mutation rates in human sperm

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Single-cell systems biology by super-resolution imaging and combinatorial labeling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Multi-layered stochasticity and paracrine signal propagation shape the type-I interferon response

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Stochastic expression of the interferon-β gene

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Single-cell proteomic chip for profiling intracellular signaling pathways in single tumor cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Single-cell gene-expression profiling reveals qualitatively distinct CD8 T cells elicited by different gene-based vaccines.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Role of cell-to-cell variability in activating a positive feedback antiviral response in human dendritic cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Paired analysis of TCRα and TCRβ chains at the single-cell level in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Analysis of genes, transcripts, and proteins via DNA ligation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Single-cell NF-kappaB dynamics reveal digital activation and analogue information processing.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

One naive T cell, multiple fates in CD8+ T cell differentiation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Short-term memory in gene induction reveals the regulatory principle behind stochastic IL-4 expression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

RNA-Seq analysis to capture the transcriptome landscape of a single cell

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Cyclophosphamide enhances immunity by modulating the balance of dendritic cell subsets in lymphoid organs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Single-molecule approaches to stochastic gene expression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Integrated barcode chips for rapid, multiplexed analysis of proteins in microliter quantities of blood

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Dynamic proteomics of individual cancer cells in response to a drug.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Imaging individual mRNA molecules using multiple singly labeled probes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Variability and robustness in T cell activation from regulated heterogeneity in protein levels

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Genetic therapies against HIV.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

A model of immune regulation as a consequence of randomized lymphocyte division and death times

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Phenotypic consequences of promoter-mediated transcriptional noise

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Noise in protein expression scales with natural protein abundance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

A microengraving method for rapid selection of single cells producing antigen-specific antibodies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Divide and conquer: division of labor by B-1 B cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

B cell selection and susceptibility to autoimmunity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Unraveling V(D)J recombination; insights into gene regulation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

T-cell-receptor gene therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Protein detection using proximity-dependent DNA ligation assays.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Positive selection of thymocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosome 4.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Whole genome amplification from a single cell: implications for genetic analysis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

V(D)J recombination: molecular biology and regulation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Mapping cellular hierarchy by single-cell analysis of the cell surface repertoire

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Cell-to-cell variability analysis dissects the plasticity of signaling of common γ chain cytokines in T cells.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Maintaining system homeostasis: the third law of Newtonian immunology

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Amplification and analysis of DNA sequences in single human sperm and diploid cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Diversity among memory B cells: origin, consequences, and utility.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

In situ sequencing for RNA analysis in preserved tissue and cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Diverse and heritable lineage imprinting of early haematopoietic progenitors.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Heterogeneous differentiation patterns of individual CD8+ T cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Activation-induced B cell fates are selected by intracellular stochastic competition.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

A single naive CD8+ T cell precursor can develop into diverse effector and memory subsets.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Probabilistic regulation in TH2 cells accounts for monoallelic expression of IL-4 and IL-13.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Probabilistic regulation of IL-4 production in Th2 cells: accessibility at the Il4 locus

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Independent and epigenetic regulation of the interleukin-4 alleles in CD4+ T cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Single-cell PCR analysis of TCR repertoires selected by antigen in vivo: a high magnitude CD8 response is comprised of very few clones.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4035247

Monoallelic expression of the interleukin-2 locus

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/24746883

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation of IL-4 expression by activation of individual alleles

1 reference

https://pubmed.ncbi.nlm.nih.gov/24746883