Structure of the MutLα C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site (Q27684073)

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24 February 2020

title

Structure of the MutLα C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site (English)

1 reference

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Rad2 family nuclease EXO1 YOR033C

24 February 2020

main subject

1 reference

Bifunctional N-glycosylase/AP lyase NTG2 YOL043C

1 reference

ATP-binding mismatch repair protein YNL082W

1 reference

Mismatch repair ATPase MLH1 YMR167W

1 reference

Mismatch repair protein MLH3 YPL164C

1 reference

author

Pierre Legrand

3

1 reference

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24 February 2020

Muriel Gondry

12

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Jean-Baptiste Charbonnier

24 February 2020

14

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24 February 2020

author name string

Emeric Gueneau

1

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24 February 2020

Claudine Dherin

2

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24 February 2020

Carine Tellier-Lebegue

4

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24 February 2020

Bernard Gilquin

5

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24 February 2020

Pierre Bonnesoeur

6

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24 February 2020

Floriana Londino

7

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24 February 2020

Cathy Quemener

8

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24 February 2020

Marie-Hélene Le Du

9

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24 February 2020

Josan A Márquez

10

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24 February 2020

Mireille Moutiez

11

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24 February 2020

Serge Boiteux

13

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24 February 2020

publication date

24 February 2013

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Nature Structural & Molecular Biology

24 February 2020

published in

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24 February 2020

volume

20

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24 February 2020

issue

4

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24 February 2020

page(s)

461-468

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DNA mismatch repair: functions and mechanisms

24 February 2020

cites work

1 reference

21 April 2017

1 reference

Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications

21 April 2017

1 reference

Structure of the human MutSalpha DNA lesion recognition complex

21 April 2017

1 reference

Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction

21 April 2017

1 reference

Functional residues on the surface of the N-terminal domain of yeast Pms1

21 April 2017

1 reference

Structure and function of the N-terminal 40 kDa fragment of human PMS2: a monomeric GHL ATPase

21 April 2017

1 reference

Functional studies on the candidate ATPase domains of Saccharomyces cerevisiae MutLalpha.

21 April 2017

1 reference

Mutations affecting a putative MutLalpha endonuclease motif impact multiple mismatch repair functions

21 April 2017

1 reference

The C-Terminal Domain of the MutL Homolog from Neisseria gonorrhoeae Forms an Inverted Homodimer

21 April 2017

1 reference

Structure of the endonuclease domain of MutL: unlicensed to cut.

21 April 2017

1 reference

DNA mismatch repair in eukaryotes and bacteria

21 April 2017

1 reference

Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1

21 April 2017

1 reference

Temporally and biochemically distinct activities of Exo1 during meiosis: double-strand break resection and resolution of double Holliday junctions

21 April 2017

1 reference

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

21 April 2017

1 reference

MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1

21 April 2017

1 reference

Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2

21 April 2017

1 reference

exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair

21 April 2017

1 reference

21 April 2017

1 reference

21 April 2017

A short history of SHELX

1 reference

Solving structures of protein complexes by molecular replacement with Phaser

21 April 2017

1 reference

Features and development of Coot

21 April 2017

1 reference

The Buccaneer software for automated model building. 1. Tracing protein chains

21 April 2017

1 reference

Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER

21 April 2017

1 reference

Molecular replacement with MOLREP

21 April 2017

1 reference

PROCHECK: a program to check the stereochemical quality of protein structures

21 April 2017

1 reference

MUSCLE: multiple sequence alignment with high accuracy and high throughput

21 April 2017

1 reference

The multifaceted mismatch-repair system

21 April 2017

1 reference

Dynamic basis for one-dimensional DNA scanning by the mismatch repair complex Msh2-Msh6.

21 January 2018

1 reference

MutS switches between two fundamentally distinct clamps during mismatch repair

21 January 2018

1 reference

The coordinated functions of the E. coli MutS and MutL proteins in mismatch repair

21 January 2018

1 reference

Endonucleolytic function of MutLalpha in human mismatch repair.

21 January 2018

1 reference

Saccharomyces cerevisiae MutLalpha is a mismatch repair endonuclease

21 January 2018

1 reference

The PMS2 subunit of human MutLalpha contains a metal ion binding domain of the iron-dependent repressor protein family

21 January 2018

1 reference

PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance

21 January 2018

1 reference

Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair

21 January 2018

1 reference

Visualizing one-dimensional diffusion of eukaryotic DNA repair factors along a chromatin lattice

21 January 2018

1 reference

Direct visualization of asymmetric adenine-nucleotide-induced conformational changes in MutL alpha

21 January 2018

1 reference

Functional domains of the Saccharomyces cerevisiae Mlh1p and Pms1p DNA mismatch repair proteins and their relevance to human hereditary nonpolyposis colorectal cancer-associated mutations

21 January 2018

1 reference

The E705K mutation in hPMS2 exerts recessive, not dominant, effects on mismatch repair

21 January 2018

1 reference

Structure of the MutL C-terminal domain: a model of intact MutL and its roles in mismatch repair

21 January 2018

1 reference

Analysis of the quaternary structure of the MutL C-terminal domain

21 January 2018

1 reference

Accurate classification of MLH1/MSH2 missense variants with multivariate analysis of protein polymorphisms-mismatch repair (MAPP-MMR).

21 January 2018

1 reference

Identification of Lynch syndrome mutations in the MLH1-PMS2 interface that disturb dimerization and mismatch repair

21 January 2018

1 reference

Mapping the dimer interface in the C-terminal domains of the yeast MLH1-PMS1 heterodimer.

21 January 2018

1 reference

Ntg2p, a Saccharomyces cerevisiae DNA N-glycosylase/apurinic or apyrimidinic lyase involved in base excision repair of oxidative DNA damage, interacts with the DNA mismatch repair protein Mlh1p. Identification of a Mlh1p binding motif.

21 January 2018

1 reference

Interactions of Exo1p with components of MutLalpha in Saccharomyces cerevisiae

21 January 2018

1 reference

Characterization of a highly conserved binding site of Mlh1 required for exonuclease I-dependent mismatch repair

21 January 2018

1 reference

Adenosine triphosphate stimulates Aquifex aeolicus MutL endonuclease activity

21 January 2018

1 reference

Local interactions in protein folding: lessons from the alpha-helix

21 January 2018

1 reference

Mimicry by asx- and ST-turns of the four main types of beta-turn in proteins.

21 January 2018

1 reference

Modeller: generation and refinement of homology-based protein structure models

21 January 2018

1 reference

A mutation in EXO1 defines separable roles in DNA mismatch repair and post-replication repair.

21 January 2018

1 reference

PBEQ-Solver for online visualization of electrostatic potential of biomolecules

21 January 2018

1 reference

High efficiency transformation of Escherichia coli with plasmids

21 January 2018

1 reference

Iterated profile searches with PSI-BLAST--a tool for discovery in protein databases

21 January 2018

1 reference

Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) Diagnostics

21 January 2018

1 reference

Functional analysis of human MLH1 variants using yeast and in vitro mismatch repair assays

21 January 2018

1 reference

Analysis of interactions between mismatch repair initiation factors and the replication processivity factor PCNA

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.2511

2 references

Consolidated OpenCitations Corpus – April 2017

2177851

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Dimensions Publication ID

24 February 2020

1007003594

0 references

2177851

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

2177851

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