Application of single-cell genomics in cancer: promise and challenges (Q28085411)

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18 February 2020

review article

2 references

8 February 2021

Application of single-cell genomics in cancer: promise and challenges (English)

2 references

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18 February 2020

1 reference

19 September 2019

1 reference

25 November 2020

1 reference

8 February 2021

2

1 reference

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18 February 2020

author name string

Quin F Wills

series ordinal

1

1 reference

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18 February 2020

language of work or name

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25 June 2015

1 reference

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18 February 2020

15 October 2015

2 references

25 November 2020

8 February 2021

Human Molecular Genetics

6 references

3 April 2019

19 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26113645%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

25 November 2020

8 February 2021

24

2 references

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18 February 2020

issue

R1

2 references

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18 February 2020

page(s)

R74-84

2 references

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Creative Commons Attribution 4.0 International

18 February 2020

copyright license

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on focus list of Wikimedia project

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Single-cell analyses of transcriptional heterogeneity during drug tolerance transition in cancer cells by RNA sequencing.

29 September 2017

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Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

29 September 2017

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29 September 2017

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Single-cell technologies sharpen up mammalian stem cell research

29 September 2017

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29 September 2017

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A quantitative comparison of single-cell whole genome amplification methods

29 September 2017

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Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Expanding the computational toolbox for mining cancer genomes

29 September 2017

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29 September 2017

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29 September 2017

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Reconstruction of the mouse otocyst and early neuroblast lineage at single-cell resolution

29 September 2017

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Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development

29 September 2017

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Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer

29 September 2017

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Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq

29 September 2017

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Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by single-cell sequencing

29 September 2017

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29 September 2017

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Highly multiplexed subcellular RNA sequencing in situ

29 September 2017

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Single cell analysis of cancer genomes

29 September 2017

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Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

29 September 2017

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29 September 2017

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29 September 2017

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Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients

29 September 2017

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Efficiency of whole genome amplification of single circulating tumor cells enriched by CellSearch and sorted by FACS.

29 September 2017

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Massively parallel polymerase cloning and genome sequencing of single cells using nanoliter microwells

29 September 2017

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Single-cell methylome landscapes of mouse embryonic stem cells and early embryos analyzed using reduced representation bisulfite sequencing

29 September 2017

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29 September 2017

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Single-cell mutational profiling and clonal phylogeny in cancer

29 September 2017

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Single-cell DNA-methylation analysis reveals epigenetic chimerism in preimplantation embryos

29 September 2017

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Single-cell sequencing-based technologies will revolutionize whole-organism science

29 September 2017

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Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing

29 September 2017

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viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia

29 September 2017

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Single-cell paired-end genome sequencing reveals structural variation per cell cycle

29 September 2017

1 reference

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Two methods for full-length RNA sequencing for low quantities of cells and single cells

29 September 2017

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Circulating tumor cells: liquid biopsy of cancer

29 September 2017

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Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis

29 September 2017

1 reference

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CEL-Seq: single-cell RNA-Seq by multiplexed linear amplification

29 September 2017

1 reference

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Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4571998

Genome-wide single-cell analysis of recombination activity and de novo mutation rates in human sperm

29 September 2017

1 reference

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From single cells to deep phenotypes in cancer

29 September 2017

1 reference

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Genome-wide copy number analysis of single cells.

29 September 2017

1 reference

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Microfluidic single cell analysis: from promise to practice

29 September 2017

1 reference

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Cancer stem cells: impact, heterogeneity, and uncertainty

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4571998

Clonal architecture of secondary acute myeloid leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4571998

Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4571998

Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4571998

DNA breaks and chromosome pulverization from errors in mitosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4571998

Counting absolute numbers of molecules using unique molecular identifiers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4571998

Whole-genome molecular haplotyping of single cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4571998

Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4571998

Whole-genome multiple displacement amplification from single cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4571998

Combined transcriptome and genome analysis of single micrometastatic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4571998

Accounting for technical noise in single-cell RNA-seq experiments.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4571998

Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4571998

Genetic variegation of clonal architecture and propagating cells in leukaemia

2 June 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV235

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV235

Persistent malignant stem cells in del(5q) myelodysplasia in remission

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV235

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV235

Single-cell sequencing in its prime

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV235

Assessment of MDA efficiency for genotyping using cloned embryo biopsies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV235

Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV235

Stochasticity of metabolism and growth at the single-cell level.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV235

Single-cell gene expression analysis reveals genetic associations masked in whole-tissue experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV235

Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4571998

Reconstructing complex tissues from single-cell analyses

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/26113645

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cancer drug prices and the free-market forces

1 reference

https://pubmed.ncbi.nlm.nih.gov/26113645

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/HMG/DDV235

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26113645%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26113645%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

PubMed publication ID

26113645

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26113645%20AND%20SRC:MED&resulttype=core&format=json