Human laminopathies: nuclei gone genetically awry (Q28276671)

The nuclear lamina comes of age.

Europe PubMed Central

title

Human laminopathies: nuclei gone genetically awry (English)

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author

Francis Collins

series ordinal

2

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Brian C Capell

series ordinal

1

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language of work or name

English

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publication date

December 2006

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published in

Nature Reviews Genetics

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volume

7

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issue

12

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page(s)

940-52

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cites work

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Dermal fibroblasts in Hutchinson-Gilford progeria syndrome with the lamin A G608G mutation have dysmorphic nuclei and are hypersensitive to heat stress

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice

31 March 2020

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Prelamin A and lamin A appear to be dispensable in the nuclear lamina

31 March 2020

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31 March 2020

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A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria.

31 March 2020

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A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation.

31 March 2020

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31 March 2020

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31 March 2020

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Aging syndrome genes and premature coronary artery disease

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Expression of an LMNA-N195K variant of A-type lamins results in cardiac conduction defects and death in mice.

31 March 2020

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Mouse model carrying H222P- Lmna mutation develops muscular dystrophy and dilated cardiomyopathy similar to human striated muscle laminopathies

31 March 2020

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Statins and their role in vascular protection

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