MAPK signaling in inflammation-associated cancer development (Q28394852)

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

Europe PubMed Central

title

MAPK signaling in inflammation-associated cancer development (English)

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Pengyu Huang

1

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Jiahuai Han

series ordinal

2

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Lijian Hui

series ordinal

3

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language of work or name

English

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publication date

March 2010

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published in

Protein & Cell

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volume

1

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issue

3

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page(s)

218-26

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cites work

1 reference

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Extracellular signal-regulated kinase 2 is necessary for mesoderm differentiation

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The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase

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MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha

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MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines

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Deficiency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells

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JNK is required for effector T-cell function but not for T-cell activation

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The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

19 March 2017

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Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis

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MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis

19 March 2017

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19 March 2017

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Identification of RIP1 kinase as a specific cellular target of necrostatins

7 April 2017

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Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

7 April 2017

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Role of autophagy in cancer

7 April 2017

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Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

7 April 2017

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AP-1: a double-edged sword in tumorigenesis

7 April 2017

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9 May 2017

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Signal integration by JNK and p38 MAPK pathways in cancer development

29 September 2017

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Erk1/2 MAP kinases are required for epidermal G2/M progression

29 September 2017

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Regulation of the immune response by stress-activated protein kinases

29 September 2017

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29 September 2017

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Dual-specificity phosphatases: critical regulators with diverse cellular targets

29 September 2017

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29 September 2017

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Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation

29 September 2017

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29 September 2017

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p38 alpha MAPK inhibits JNK activation and collaborates with IkappaB kinase 2 to prevent endotoxin-induced liver failure

29 September 2017

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Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis

29 September 2017

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The kinase p38 alpha serves cell type-specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expression

29 September 2017

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Dual-specificity MAP kinase phosphatases (MKPs) and cancer

29 September 2017

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p38alpha: a suppressor of cell proliferation and tumorigenesis

29 September 2017

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Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1-dependent expression of inducible nitric oxide synthase

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c-Jun NH2-terminal kinase 1 plays a critical role in intestinal homeostasis and tumor suppression

29 September 2017

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Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: a perspective.

29 September 2017

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Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation

29 September 2017

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ERK implication in cell cycle regulation

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DUSP meet immunology: dual specificity MAPK phosphatases in control of the inflammatory response

29 September 2017

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Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Raf-independent deregulation of p38 and JNK mitogen-activated protein kinases are critical for Ras transformation

29 September 2017

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29 September 2017

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2 June 2018

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2 June 2018

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Macrophage deletion of p38alpha partially impairs lipopolysaccharide-induced cellular activation.

2 June 2018

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p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway

27 November 2018

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Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1.

27 November 2018

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IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis

27 November 2018

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The extracellular signal-regulated kinase isoform ERK1 is specifically required for in vitro and in vivo adipogenesis

27 November 2018

1 reference

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MKK7 couples stress signalling to G2/M cell-cycle progression and cellular senescence.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875080

Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway

27 November 2018

1 reference

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Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors

27 November 2018

1 reference

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Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory

27 November 2018

1 reference

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Deficiency of c-Jun-NH(2)-terminal kinase-1 in mice enhances skin tumor development by 12-O-tetradecanoylphorbol-13-acetate.

27 November 2018

1 reference

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Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2.

27 November 2018

1 reference

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The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development

27 November 2018

1 reference

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Chemical genetic analysis of the time course of signal transduction by JNK

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12 December 2020

Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development

1 reference

12 December 2020

Chronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult Mice

1 reference

12 December 2020

JNK2 is a positive regulator of the cJun transcription factor

1 reference

12 December 2020

The specific JNK inhibitor SP600125 targets tumour necrosis factor-alpha production and epithelial cell apoptosis in acute murine colitis

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12 December 2020

Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis

1 reference

12 December 2020

Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro

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12 December 2020

Genetic deletion of JNK1 and JNK2 aggravates the DSS-induced colitis in mice

1 reference

12 December 2020

The JNK signal transduction pathway

1 reference

12 December 2020

Dissection of the intracellular pathways in hepatocytes suggests a role for Jun kinase and IFN regulatory factor-1 in Con A-induced liver failure

1 reference

12 December 2020

p38α MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation

1 reference

12 December 2020

IKKβ Is Required for Prevention of Apoptosis Mediated by Cell-Bound but Not by Circulating TNFα

1 reference

12 December 2020

10.1007/S13238-010-0019-9

Identifiers

DOI

1 reference

Dimensions Publication ID

1019921113

0 references

1 reference

1 reference

PubMed publication ID

21203968

1 reference