Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance (Q28512935)

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Language	Label	Description	Also known as
English	Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance	scientific journal article

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scholarly article

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25 January 2017

Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance (English)

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25 January 2017

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Insulin-like growth factor 1

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GOA release 2020-03-11

Insulin receptor

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GOA release 2020-03-11

Insulin-like growth factor I receptor

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GOA release 2020-03-11

Insulin-like growth factor 2

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GOA release 2020-03-11

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based on heuristic

inferred from title

insulin resistance

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based on heuristic

inferred from title

Domenico Accili

6

object named as

Domenico Accili

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25 January 2017

Argiris Efstratiadis

5

object named as

Argiris Efstratiadis

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25 January 2017

author name string

Yoshiaki Kido

1

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25 January 2017

Jun Nakae

2

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25 January 2017

Marta Letizia Hribal

3

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25 January 2017

Shouhong Xuan

4

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25 January 2017

language of work or name

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publication date

27 September 2002

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25 January 2017

Journal of Biological Chemistry

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25 January 2017

277

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25 January 2017

39

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25 January 2017

36740–36747

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25 January 2017

Genetics of type 2 diabetes: insight from targeted mouse mutants

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https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

New perspectives into the molecular pathogenesis and treatment of type 2 diabetes

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https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Impaired glucose tolerance in mice with a targeted impairment of insulin action in muscle and adipose tissue.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes

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https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

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https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines

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https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Disruption of IRS-2 causes type 2 diabetes in mice

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https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Perspective: Postnatal pancreatic beta cell growth

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https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Hypoglycemic effect of insulin-like growth factor-1 in mice lacking insulin receptors

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https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Evidence that IRS-2 phosphorylation is required for insulin action in hepatocytes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Differential signaling of insulin and IGF-1 receptors to glycogen synthesis in murine hepatocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Mitogenic and metabolic effects of type I IGF receptor overexpression in insulin receptor-deficient hepatocytes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Differential signaling to glycogen synthesis by the intracellular domain of the insulin versus the insulin-like growth factor-1 receptor. Evidence from studies of TrkC-chimeras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Differences in signaling properties of the cytoplasmic domains of the insulin receptor and insulin-like growth factor receptor in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

IGF-I--stimulated glucose transport in human skeletal muscle and IGF-I resistance in obesity and NIDDM.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Exercise modulates postreceptor insulin signaling and glucose transport in muscle-specific insulin receptor knockout mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Genetic modifiers of the insulin resistance phenotype in mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Role of insulin-like growth factors in embryonic and postnatal growth

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https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith-Wiedemann and Simpson-Golabi-Behmel syndromes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Intercellular signals regulating pancreas development and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Targeted expression of placental lactogen in the beta cells of transgenic mice results in beta cell proliferation, islet mass augmentation, and hypoglycemia.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Insulin-promoter-factor 1 is required for pancreas development in mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Signaling through fibroblast growth factor receptor 2b plays a key role in the development of the exocrine pancreas.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Fibroblast growth factor 2 promotes pancreatic epithelial cell proliferation via functional fibroblast growth factor receptors during embryonic life.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

TGF-beta plays a key role in morphogenesis of the pancreatic islets of Langerhans by controlling the activity of the matrix metalloproteinase MMP-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Ontogeny of activin B and follistatin in developing embryonic mouse pancreas: implications for lineage selection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Regulation of gene expression by insulin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Transdominant inhibition of tyrosine kinase activity in mutant insulin/insulin-like growth factor I hybrid receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Attenuation of FGF signalling in mouse β-cells leads to diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206314200

21 January 2018

Identifiers

10.1074/JBC.M206314200

0 references

1 reference

25 January 2017

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