Inactivation of BAD by IKK inhibits TNFα-induced apoptosis independently of NF-κB activation (Q28588152)

31 January 2017

title

Inactivation of BAD by IKK inhibits TNFα-induced apoptosis independently of NF-κB activation (English)

1 reference

BCL2-associated agonist of cell death

31 January 2017

0 references

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1 reference

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

Jie Yan

1

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31 January 2017

Jialing Xiang

2

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31 January 2017

Yutin Lin

3

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31 January 2017

Jingui Ma

4

1 reference

31 January 2017

Jiyan Zhang

5

1 reference

31 January 2017

Hao Zhang

6

1 reference

31 January 2017

Jisheng Sun

7

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31 January 2017

Nika N. Danial

8

1 reference

31 January 2017

Jing Liu

9

1 reference

31 January 2017

Anning Lin

10

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31 January 2017

language of work or name

English

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publication date

17 January 2013

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31 January 2017

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31 January 2017

volume

152

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31 January 2017

issue

1-2

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31 January 2017

page(s)

304–315

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Wiring the cell signaling circuitry by the NF-kappa B and JNK1 crosstalk and its applications in human diseases

31 January 2017

cites work

1 reference

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The Bcl-2 apoptotic switch in cancer development and therapy

17 March 2017

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IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

17 March 2017

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JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD

17 March 2017

1 reference

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Cell death: critical control points

17 March 2017

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

17 March 2017

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Rsk1 mediates a MEK-MAP kinase cell survival signal

17 March 2017

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Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

17 March 2017

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IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

17 March 2017

1 reference

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

17 March 2017

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IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

17 March 2017

1 reference

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3586589

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

17 March 2017

1 reference

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Bcl-2 targets the protein kinase Raf-1 to mitochondria

17 March 2017

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Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

17 March 2017

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Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

17 March 2017

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Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

17 March 2017

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The BCL-2 protein family: opposing activities that mediate cell death

17 March 2017

1 reference

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Missing pieces in the NF-kappaB puzzle

7 April 2017

1 reference

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

7 April 2017

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NF-kappaB at the crossroads of life and death

7 April 2017

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Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

7 April 2017

1 reference

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Suppression of TNF-alpha-induced apoptosis by NF-kappaB

7 April 2017

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Regulation of cell death and autophagy by IKK and NF-κB: critical mechanisms in immune function and cancer

7 April 2017

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29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3586589

p85α SH2 domain phosphorylation by IKK promotes feedback inhibition of PI3K and Akt in response to cellular starvation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3586589

BAD: undertaker by night, candyman by day.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3586589

IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway

29 September 2017

1 reference

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If the prophet does not come to the mountain: dynamics of signaling complexes in NF-kappaB activation

29 September 2017

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Circuitry of nuclear factor kappaB signaling

29 September 2017

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Regulation of the deubiquitinating enzyme CYLD by IkappaB kinase gamma-dependent phosphorylation

29 September 2017

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c-Jun N-terminal protein kinase 1 (JNK1), but not JNK2, is essential for tumor necrosis factor alpha-induced c-Jun kinase activation and apoptosis

29 September 2017

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Bad-deficient mice develop diffuse large B cell lymphoma

29 September 2017

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The absence of NF-kappaB-mediated inhibition of c-Jun N-terminal kinase activation contributes to tumor necrosis factor alpha-induced apoptosis

29 September 2017

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How do 14-3-3 proteins work?-- Gatekeeper phosphorylation and the molecular anvil hypothesis

29 September 2017

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Signal transduction by tumor necrosis factor and its relatives

29 September 2017

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Severe liver degeneration and lack of NF-kappaB activation in NEMO/IKKgamma-deficient mice

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3586589

Control of apoptosis by Rel/NF-kappaB transcription factors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3586589

Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: transgenics and knockouts

29 September 2017

1 reference

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The combined absence of the transcription factors Rel and RelA leads to multiple hemopoietic cell defects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3586589

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3586589

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3586589

Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3586589

Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3586589

Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation.

3 June 2018

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A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3586589

Inhibition of JNK activation through NF-kappaB target genes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3586589

Targeted mutation of TNF receptor I rescues the RelA-deficient mouse and reveals a critical role for NF-kappa B in leukocyte recruitment

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/23332762

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Signal transduction pathways that regulate cell survival and cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/23332762

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A

1 reference

https://pubmed.ncbi.nlm.nih.gov/23332762

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2012.12.021

1 reference

1 reference

1 reference

1 reference