Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntington's disease (Q28594357)

31 January 2017

title

Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntington's disease (English)

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31 January 2017

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Fengli Wang

1

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31 January 2017

Yeran Yang

2

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31 January 2017

Xiwen Lin

3

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31 January 2017

Jiu-Qiang Wang

4

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31 January 2017

Yong-Sheng Wu

5

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31 January 2017

Wenjuan Xie

6

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31 January 2017

Dandan Wang

7

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31 January 2017

Shu Zhu

8

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31 January 2017

You-Qi Liao

9

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31 January 2017

Qinmiao Sun

10

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31 January 2017

Yun-Gui Yang

11

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31 January 2017

Huai-Rong Luo

12

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31 January 2017

Caixia Guo

13

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31 January 2017

Chunsheng Han

14

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31 January 2017

Tie-Shan Tang

15

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31 January 2017

publication date

15 September 2013

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31 January 2017

published in

Human Molecular Genetics

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31 January 2017

volume

22

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31 January 2017

issue

18

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31 January 2017

page(s)

3641–3653

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

31 January 2017

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Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage

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21 January 2018

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What have we learned from gene expression profiles in Huntington's disease?

21 January 2018

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Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease

21 January 2018

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Selective degeneration and nuclear localization of mutant huntingtin in the YAC128 mouse model of Huntington disease

21 January 2018

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Dopaminergic signaling and striatal neurodegeneration in Huntington's disease

21 January 2018

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Mitochondrial sensitivity and altered calcium handling underlie enhanced NMDA-induced apoptosis in YAC128 model of Huntington's disease.

21 January 2018

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Expression analysis of novel striatal-enriched genes in Huntington disease

21 January 2018

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Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine

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Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease

21 January 2018

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Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease.

21 January 2018

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Altered NMDA receptor trafficking in a yeast artificial chromosome transgenic mouse model of Huntington's disease.

21 January 2018

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Decreased cAMP response element-mediated transcription: an early event in exon 1 and full-length cell models of Huntington's disease that contributes to polyglutamine pathogenesis

21 January 2018

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CREB is a key regulator of striatal vulnerability in chemical and genetic models of Huntington's disease

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis

21 January 2018

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Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Huntingtin interacts with a family of WW domain proteins

21 January 2018

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Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models

21 January 2018

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Genome-wide histone acetylation is altered in a transgenic mouse model of Huntington's disease

21 January 2018

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ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease

21 January 2018

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21 January 2018

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21 January 2018

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Human DNA methylomes at base resolution show widespread epigenomic differences

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma

21 January 2018

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Dysregulation of mitochondrial calcium signaling and superoxide flashes cause mitochondrial genomic DNA damage in Huntington disease

21 January 2018

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Wnt signalling regulates adult hippocampal neurogenesis

21 January 2018

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Beta-catenin signaling promotes proliferation of progenitor cells in the adult mouse subventricular zone

21 January 2018

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Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal

21 January 2018

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Altered adult hippocampal neurogenesis in the YAC128 transgenic mouse model of Huntington disease

21 January 2018

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Neurogenesis in Huntington's disease: can studying adult neurogenesis lead to the development of new therapeutic strategies?

21 January 2018

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Cognitive disorders and neurogenesis deficits in Huntington's disease mice are rescued by fluoxetine.

21 January 2018

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Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease

21 January 2018

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Sertraline slows disease progression and increases neurogenesis in N171-82Q mouse model of Huntington's disease

21 January 2018

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