Pro-apoptotic Bax molecules densely populate the edges of membrane pores (Q30388868)

17 August 2017

Pro-apoptotic Bax molecules densely populate the edges of membrane pores (English)

1 reference

17 August 2017

0 references

4

Bjoern Peters

1 reference

17 August 2017

Tomomi Kuwana

1

1 reference

17 August 2017

Norman H Olson

series ordinal

2

1 reference

17 August 2017

William B Kiosses

series ordinal

3

1 reference

17 August 2017

Donald D Newmeyer

series ordinal

5

1 reference

17 August 2017

language of work or name

English

0 references

publication date

3 June 2016

1 reference

17 August 2017

1 reference

17 August 2017

6

1 reference

17 August 2017

27299

1 reference

Creative Commons Attribution 4.0 International

17 August 2017

start time

1 June 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Bax assembles into large ring-like structures remodeling the mitochondrial outer membrane in apoptosis

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Bax assembly into rings and arcs in apoptotic mitochondria is linked to membrane pores.

20 June 2018

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BH3-in-groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes

20 June 2018

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Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death

20 June 2018

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Structural model of active Bax at the membrane.

20 June 2018

1 reference

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Visual and functional demonstration of growing Bax-induced pores in mitochondrial outer membranes

20 June 2018

1 reference

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Apoptotic pore formation is associated with in-plane insertion of Bak or Bax central helices into the mitochondrial outer membrane

20 June 2018

1 reference

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Apoptosis regulation at the mitochondrial outer membrane

20 June 2018

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Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy.

20 June 2018

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Organization of the mitochondrial apoptotic BAK pore: oligomerization of the BAK homodimers

20 June 2018

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BIM-mediated membrane insertion of the BAK pore domain is an essential requirement for apoptosis

20 June 2018

1 reference

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Process of inducing pores in membranes by melittin

20 June 2018

1 reference

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Three-dimensional structure of Bax-mediated pores in membrane bilayers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Membrane permeability of hydrocarbon-cross-linked peptides

20 June 2018

1 reference

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The discreet charm of the curve

20 June 2018

1 reference

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Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis

20 June 2018

1 reference

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Where killers meet--permeabilization of the outer mitochondrial membrane during apoptosis

20 June 2018

1 reference

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Bax activation initiates the assembly of a multimeric catalyst that facilitates Bax pore formation in mitochondrial outer membranes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Thermodynamic profiling of peptide membrane interactions by isothermal titration calorimetry: a search for pores and micelles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Resistance to caspase-independent cell death requires persistence of intact mitochondria

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

20 June 2018

The BCL-2 family reunion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis

20 June 2018

1 reference

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Caspase-independent mitochondrial cell death results from loss of respiration, not cytotoxic protein release.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Wasp mastoparans follow the same mechanism as the cell-penetrating peptide transportan 10.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Characterization of antibiotic peptide pores using cryo-EM and comparison to neutron scattering

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Assembly of the mitochondrial apoptosis-induced channel, MAC.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Mitochondrial outer membrane proteins assist Bid in Bax-mediated lipidic pore formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Magainin 2 revisited: a test of the quantitative model for the all-or-none permeabilization of phospholipid vesicles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Structure of transmembrane pore induced by Bax-derived peptide: evidence for lipidic pores.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

BAX activation is initiated at a novel interaction site

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Mechanism and kinetics of pore formation in membranes by water-soluble amphipathic peptides

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

The BCL-2 protein family: opposing activities that mediate cell death

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Pore formation by a Bax-derived peptide: effect on the line tension of the membrane probed by AFM.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

The X-ray structure of a BAK homodimer reveals an inhibitory zinc binding site

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

The mechanism of pore formation by bacterial toxins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Structural basis of pore formation by the bacterial toxin pneumolysin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Peptides derived from apoptotic Bax and Bid reproduce the poration activity of the parent full-length proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

PB1-F2, an influenza A virus-encoded proapoptotic mitochondrial protein, creates variably sized pores in planar lipid membranes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Cell death: critical control points

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Mitochondria: releasing power for life and unleashing the machineries of death

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Structure of Bax: coregulation of dimer formation and intracellular localization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Adding the Third Dimension to Virus Life Cycles: Three-Dimensional Reconstruction of Icosahedral Viruses from Cryo-Electron Micrographs

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Bax, but not Bcl-xL, decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Conformation of the Bax C-terminus regulates subcellular location and cell death

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

Refined structure of the pore-forming domain of colicin A at 2.4 A resolution

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4891688

BH3-triggered structural reorganization drives the activation of proapoptotic BAX.

20 June 2018

1 reference

Bax-type apoptotic proteins porate pure lipid bilayers through a mechanism sensitive to intrinsic monolayer curvature.

21 January 2018

1 reference

Single giant unilamellar vesicle method reveals effect of antimicrobial peptide magainin 2 on membrane permeability

21 January 2018

1 reference

Diphtheria toxin forms pores of different sizes depending on its concentration in membranes: probable relationship to oligomerization.

21 January 2018

1 reference

Molecular details of Bax activation, oligomerization, and membrane insertion.

21 January 2018

1 reference

Peptides corresponding to helices 5 and 6 of Bax can independently form large lipid pores

21 January 2018

1 reference

Effect of lipids with different spontaneous curvature on the channel activity of colicin E1: evidence in favor of a toroidal pore

21 January 2018

1 reference

12 December 2020

Antimicrobial peptides in action

1 reference

12 December 2020

Relationship of membrane curvature to the formation of pores by magainin 2

1 reference

12 December 2020

Transbilayer transport of ions and lipids coupled with mastoparan X translocation

1 reference

12 December 2020

Identifiers

DOI

10.1038/SREP27299

1 reference

Dimensions Publication ID

17 August 2017

0 references

1 reference

17 August 2017

PubMed publication ID

27255832

1 reference