The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4. (Q33292338)

25 July 2017

The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4. (English)

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25 July 2017

1

Markus Welcker

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25 July 2017

Bruce E Clurman

2

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PubMed ID

15611062

25 July 2017

language of work or name

English

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publication date

20 December 2004

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Journal of Biological Chemistry

25 July 2017

5

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based on heuristic

inferred from page(s)

published in

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25 July 2017

280

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25 July 2017

9

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25 July 2017

7654-7658

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The retinoblastoma protein and cell cycle control

25 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Retinoblastoma protein recruits histone deacetylase to repress transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Role of LXCXE motif-dependent interactions in the activity of the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

DnaJ/hsp40 chaperone domain of SV40 large T antigen promotes efficient viral DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Species-specific elements in the large T-antigen J domain are required for cellular transformation and DNA replication by simian virus 40

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Viral oncoproteins discriminate between p53 and the p53 homolog p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Cellular transformation by SV40 large T antigen: interaction with host proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

SV40 T antigen interacts with Nbs1 to disrupt DNA replication control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Cul7/p185/p193 binding to simian virus 40 large T antigen has a role in cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

The Drosophila F box protein archipelago regulates dMyc protein levels in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

SEL-10 interacts with presenilin 1, facilitates its ubiquitination, and alters A-beta peptide production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Evidence for functional and physical association between Caenorhabditis elegans SEL-10, a Cdc4p-related protein, and SEL-12 presenilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Inactivation of hCDC4 can cause chromosomal instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

D-type cyclin-dependent kinase activity in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

hCDC4b, a regulator of cyclin E, as a direct transcriptional target of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

In vitro phosphorylation of SV40 large T antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Notch-1 induction, a novel activity of SV40 required for growth of SV40-transformed human mesothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

Simian virus 40 in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413377200

21 January 2018

Identifiers

DOI

10.1074/JBC.M413377200

1 reference

release_npeg6aybobavra72jh7budcojq

25 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/npeg6aybobavra72jh7budcojq

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24 November 2022

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PubMed ID

15611062

1 reference

PubMed ID

15611062