Molecular controls of antigen receptor clustering and autoimmunity (Q34228160)

31 July 2017

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title

Molecular controls of antigen receptor clustering and autoimmunity (English)

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31 July 2017

2

J M Penninger

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31 July 2017

C Krawczyk

1

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31 July 2017

1 May 2001

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31 July 2017

Trends in Cell Biology

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31 July 2017

11

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31 July 2017

212-220

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31 July 2017

5

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The thymic microenvironment.

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Tensegrity: the architectural basis of cellular mechanotransduction

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Organized endothelial cell surface signal transduction in caveolae distinct from glycosylphosphatidylinositol-anchored protein microdomains

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Signaling through scaffold, anchoring, and adaptor proteins

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Three-dimensional segregation of supramolecular activation clusters in T cells

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

T lymphocyte costimulation mediated by reorganization of membrane microdomains

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Costimulatory regulation of T cell function.

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

A cell culture model for T lymphocyte clonal anergy

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Making the T cell receptor go the distance: a topological view of T cell activation

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Tyrosine-phosphorylated Vav1 as a point of integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Vav synergizes with protein kinase C theta to mediate IL-4 gene expression in response to CD28 costimulation in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Integrin-dependent tyrosine phosphorylation and growth regulation by Vav

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Antibody-induced engagement of beta 2 integrins on adherent human neutrophils triggers activation of p21ras through tyrosine phosphorylation of the protooncogene product Vav

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Tyrosine phosphorylation of the vav proto-oncogene product in activated B cells

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Cbl-b regulates the CD28 dependence of T-cell activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

The oncogene product Vav is a crucial regulator of primary cytotoxic T cell responses but has no apparent role in CD28-mediated co-stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Identification of WASP mutations in patients with Wiskott-Aldrich syndrome and isolated thrombocytopenia reveals allelic heterogeneity at the WAS locus

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

A homochiral metal-organic porous material for enantioselective separation and catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Structure of the enabled/VASP homology 1 domain-peptide complex: a key component in the spatial control of actin assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Regulation of actin polymerization by Arp2/3 complex and WASp/Scar proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Biochemistry. Ubiquitination--more than two to tango

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

The c-cbl proto-oncogene is preferentially expressed in thymus and testis tissue and encodes a nuclear protein

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell development.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

D-Cbl, the Drosophila homologue of the c-Cbl proto-oncogene, interacts with the Drosophila EGF receptor in vivo, despite lacking C-terminal adaptor binding sites.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

cbl-3: a new mammalian cbl family protein

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domain

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

cbl-b inhibits epidermal growth factor receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

The Cbl proto-oncogene product negatively regulates the Src-family tyrosine kinase Fyn by enhancing its degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

The Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70.

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Enhancement of lymphocyte responsiveness by a gain-of-function mutation of ZAP-70.

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Differential requirements for survival and proliferation of CD8 naïve or memory T cells

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Designing and maintaining the mature TCR repertoire: the continuum of self-peptide:self-MHC complex recognition

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

The ubiquitin-proteasome pathway and serine kinase activity modulate adenomatous polyposis coli protein-mediated regulation of beta-catenin-lymphocyte enhancer-binding factor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2901981-X

7 January 2021

10.1016/S0962-8924(01)01981-X

Identifiers

DOI

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31 July 2017

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PubMed ID

11316610