Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer (Q34613635)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21122106%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer (English)

1 reference

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17 January 2020

1 reference

1 reference

2

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17 January 2020

Martin Widschwendter

3

1 reference

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17 January 2020

5

Jonas Bergh

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17 January 2020

author name string

Shahab Akhoondi

1

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17 January 2020

Martin Corcoran

4

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17 January 2020

Charles Spruck

6

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17 January 2020

Dan Grandér

7

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17 January 2020

Olle Sangfelt

8

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17 January 2020

publication date

1 December 2010

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17 January 2020

published in

Breast Cancer Research

1 reference

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17 January 2020

volume

12

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17 January 2020

issue

6

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17 January 2020

page(s)

R105

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describes a project that uses

17 January 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3046450/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1186/bcr2788

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cites work

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7 July 2018

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Fbw7 and Usp28 regulate myc protein stability in response to DNA damage

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Ubiquitylation of cyclin E requires the sequential function of SCF complexes containing distinct hCdc4 isoforms

7 July 2018

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Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

7 July 2018

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7 July 2018

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Ubiquitin ligases: cell-cycle control and cancer

7 July 2018

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Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas

7 July 2018

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An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

7 July 2018

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Infrequent mutations of Archipelago (hAGO, hCDC4, Fbw7) in primary ovarian cancer

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Inactivation of hCDC4 can cause chromosomal instability

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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FBXW7/hCDC4 is a general tumor suppressor in human cancer.

7 July 2018

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Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL.

21 January 2018

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Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

21 January 2018

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The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling.

21 January 2018

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FBXW7 and NOTCH1 mutations in childhood T cell acute lymphoblastic leukaemia and T cell non-Hodgkin lymphoma

21 January 2018

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p53-Altered FBXW7 expression determines poor prognosis in gastric cancer cases.

21 January 2018

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Methylated NEUROD1 promoter is a marker for chemosensitivity in breast cancer.

21 January 2018

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Mutational and LOH analyses of the chromosome 4q region in esophageal adenocarcinoma.

21 January 2018

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Can molecular markers predict when to implement treatment with aromatase inhibitors in invasive breast cancer?

21 January 2018

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Fbw7 regulates the activity of endoreduplication mediators and the p53 pathway to prevent drug-induced polyploidy.

21 January 2018

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Prognostic relevance of promoter hypermethylation of multiple genes in breast cancer patients.

21 January 2018

1 reference

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Functional analysis of CpG methylation in the BRCA1 promoter region

26 October 2018

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12 December 2020

BRCA1 promoter methylation predicts adverse ovarian cancer prognosis

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12 December 2020

DNA methylation markers - an opportunity to further individualize therapy in breast cancer?

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12 December 2020

Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy

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12 December 2020

The fundamental role of epigenetic events in cancer

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12 December 2020

Identifiers

DOI

10.1186/BCR2788

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21122106%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

17 January 2020

1040598960

0 references

Fatcat ID

release_77yblw2oyfcufh7uqbsco7tifm

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/77yblw2oyfcufh7uqbsco7tifm

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21122106%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference