MEK-ERK pathway modulation ameliorates disease phenotypes in a mouse model of Noonan syndrome associated with the Raf1(L613V) mutation (Q34627221)

3 August 2017

MEK-ERK pathway modulation ameliorates disease phenotypes in a mouse model of Noonan syndrome associated with the Raf1(L613V) mutation (English)

1 reference

3 August 2017

1 reference

Xue Wu

1

1 reference

3 August 2017

Jeremy Simpson

2

1 reference

3 August 2017

Jenny H Hong

3

1 reference

3 August 2017

Kyoung-Han Kim

4

1 reference

3 August 2017

Nirusha K Thavarajah

5

1 reference

3 August 2017

Peter H Backx

6

1 reference

3 August 2017

Benjamin G Neel

7

1 reference

3 August 2017

Toshiyuki Araki

8

1 reference

3 August 2017

language of work or name

English

0 references

publication date

21 February 2011

1 reference

Journal of Clinical Investigation

3 August 2017

1 reference

3 August 2017

121

1 reference

3 August 2017

1009-1025

1 reference

3 August 2017

3

1 reference

describes a project that uses

3 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3049402/fullTextXML

inferred from PubMed Central ID database lookup

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Regulation of cardiac contraction

7 July 2018

1 reference

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7 July 2018

1 reference

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26 October 2018

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The spectrum of cardiac anomalies in Noonan syndrome as a result of mutations in the PTPN11 gene.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049402

Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome.

26 October 2018

1 reference

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Electrotonic modulation of cardiac impulse conduction by myofibroblasts.

26 October 2018

1 reference

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Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome

26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: a role in cardiac myocyte hypertrophy?

26 October 2018

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Ventricular expression of a MLC-2v-ras fusion gene induces cardiac hypertrophy and selective diastolic dysfunction in transgenic mice.

26 October 2018

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Distinct gene expression profiles in adult mouse heart following targeted MAP kinase activation

26 October 2018

1 reference

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Depletion of mitogen-activated protein kinase using an antisense oligodeoxynucleotide approach downregulates the phenylephrine-induced hypertrophic response in rat cardiac myocytes

9 December 2018

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12 December 2020

Hypertrophic cardiomyopathy in Noonan syndrome

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12 December 2020

Further delineation of the phenotype resulting from BRAF or MEK1 germline mutations helps differentiate cardio-facio-cutaneous syndrome from Costello syndrome

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12 December 2020

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12 December 2020

Mutation analysis of AMP-activated protein kinase subunits in inherited cardiomyopathies: implications for kinase function and disease pathogenesis

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12 December 2020

Identifiers

DOI

10.1172/JCI44929

1 reference

3 August 2017

1 reference

3 August 2017

1 reference