Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization (Q34944325)

5 August 2017

title

Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization (English)

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5 August 2017

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13

Birgit Liss

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J. Eschbach

series ordinal

1

object named as

Eschbach J

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5 August 2017

2

von Einem B

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3

Müller K

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4

Bayer H

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5

Scheffold A

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6

Morrison BE

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Rudolph KL

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8

Thal DR

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9

Witting A

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10

Weydt P

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11

Otto M

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12

Fauler M

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14

McLean PJ

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15

Spada AR

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Ludolph AC

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Weishaupt JH

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Danzer KM

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5 August 2017

language of work or name

English

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publication date

19 December 2014

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5 August 2017

number of pages

18

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inferred from page(s)

published in

Annals of Neurology

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5 August 2017

volume

77

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5 August 2017

issue

1

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5 August 2017

page(s)

15-32

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describes a project that uses

5 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4293280/fullTextXML

inferred from PubMed Central ID database lookup

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

8 July 2018

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8 July 2018

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8 July 2018

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Overexpression of peroxisome proliferator-activated receptor gamma co-activator-1alpha leads to muscle atrophy with depletion of ATP

8 July 2018

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8 July 2018

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Expanding insights of mitochondrial dysfunction in Parkinson's disease.

8 July 2018

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Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system

8 July 2018

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Rotenone model of Parkinson disease: multiple brain mitochondria dysfunctions after short term systemic rotenone intoxication

8 July 2018

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PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis

8 July 2018

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MPTP as a mitochondrial neurotoxic model of Parkinson's disease

8 July 2018

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Prefibrillar amyloid protein aggregates share common features of cytotoxicity.

8 July 2018

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

8 July 2018

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Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

8 July 2018

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Characterization of the peroxisome proliferator activated receptor coactivator 1 alpha (PGC 1alpha) expression in the murine brain

8 July 2018

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Motor dysfunction and gliosis with preserved dopaminergic markers in human alpha-synuclein A30P transgenic mice

8 July 2018

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Staging of brain pathology related to sporadic Parkinson's disease

8 July 2018

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Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies

8 July 2018

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An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage.

8 July 2018

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Alpha-synuclein and neurodegenerative diseases

8 July 2018

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Physiology and pathophysiology of alpha-synuclein. Cell culture and transgenic animal models based on a Parkinson's disease-associated protein.

8 July 2018

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

8 July 2018

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Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis

8 July 2018

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alpha-synuclein promotes mitochondrial deficit and oxidative stress

8 July 2018

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Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

8 July 2018

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Alpha-synuclein in Lewy bodies

8 July 2018

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Mitochondrial complex I deficiency in Parkinson's disease

8 July 2018

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Golgi fragmentation occurs in the cells with prefibrillar alpha-synuclein aggregates and precedes the formation of fibrillar inclusion

8 July 2018

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Neurodegenerative disease: amyloid pores from pathogenic mutations.

21 January 2018

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Different species of alpha-synuclein oligomers induce calcium influx and seeding.

21 January 2018

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Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

21 January 2018

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Oxidative stress involvement in alpha-synuclein oligomerization in Parkinson's disease cybrids

21 January 2018

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Selective microglial activation in the rat rotenone model of Parkinson's disease

21 January 2018

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Neuroprotective effect of protein kinase C delta inhibitor rottlerin in cell culture and animal models of Parkinson's disease

21 January 2018

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21 January 2018

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PGC-1alpha as modifier of onset age in Huntington disease

21 January 2018

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Locomotor activity and evoked dopamine release are reduced in mice overexpressing A30P-mutated human alpha-synuclein

21 January 2018

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Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration

21 January 2018

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Age-dependent cognitive decline and amygdala pathology in alpha-synuclein transgenic mice

21 January 2018

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Effect of exercise intensity and AICAR on isoform-specific expressions of murine skeletal muscle PGC-1α mRNA: a role of β₂-adrenergic receptor activation.

21 January 2018

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Seeding induced by alpha-synuclein oligomers provides evidence for spreading of alpha-synuclein pathology

21 January 2018

1 reference

Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner

21 January 2018

1 reference

Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice

21 January 2018

1 reference

Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.

21 January 2018

1 reference

Modulation of energy deficiency in Huntington's disease via activation of the peroxisome proliferator-activated receptor gamma

21 January 2018

1 reference

Resveratrol protects against peripheral deficits in a mouse model of Huntington's disease

21 January 2018

1 reference

Antioxidant compounds have potent anti-fibrillogenic and fibril-destabilizing effects for alpha-synuclein fibrils in vitro

21 January 2018

1 reference

Parkinson's disease in a chemist working with 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

21 January 2018

1 reference

12 December 2020

Detection of oligomeric forms of alpha-synuclein protein in human plasma as a potential biomarker for Parkinson's disease

1 reference

12 December 2020

A highly sensitive protein-protein interaction assay based on Gaussia luciferase

1 reference

12 December 2020

PGC-1α protects neurons and alters disease progression in an amyotrophic lateral sclerosis mouse model

1 reference

12 December 2020

Beta-synuclein inhibits formation of alpha-synuclein protofibrils: a possible therapeutic strategy against Parkinson's disease

1 reference

12 December 2020

Identifiers

DOI

10.1002/ANA.24294

1 reference

5 August 2017

1 reference

5 August 2017

1 reference