Emetine Promotes von Hippel-Lindau-Independent Degradation of Hypoxia-Inducible Factor-2α in Clear Cell Renal Carcinoma (Q35454927)

8 August 2017

title

Emetine promotes von Hippel-Lindau-independent degradation of hypoxia-inducible factor-2α in clear cell renal carcinoma (English)

1 reference

8 August 2017

Emetine Promotes von Hippel-Lindau-Independent Degradation of Hypoxia-Inducible Factor-2α in Clear Cell Renal Carcinoma (English)

1 reference

Crossref

https://api.crossref.org/works/10.1124/MOL.110.066514

5 July 2024

9

Leonard Neckers

1 reference

8 August 2017

8

Jane Trepel

1 reference

8 August 2017

4

Bradley Scroggins

1 reference

8 August 2017

3

Kristin Beebe

1 reference

8 August 2017

5

Gopal Gupta

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813864

5 July 2024

author name string

Hye-Sik Kong

1

1 reference

8 August 2017

Sunmin Lee

2

1 reference

8 August 2017

Min-Jung Lee

6

1 reference

8 August 2017

Yun-Jin Jung

7

1 reference

8 August 2017

Bradley Scroggins

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813864

5 July 2024

Jane Trepel

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813864

5 July 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20813864

5 July 2024

publication date

2 September 2010

1 reference

full work available at URL

8 August 2017

https://europepmc.org/articles/pmc3202510?pdf=render

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813864

http://molpharm.aspetjournals.org/cgi/content/abstract/78/6/1072

5 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813864

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20813864/?tool=EBI

5 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813864

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20813864/pdf/?tool=EBI

5 July 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813864

https://europepmc.org/articles/PMC3202510

5 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813864

https://europepmc.org/articles/PMC3202510?pdf=render

5 July 2024

file format

Portable Document Format

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813864

https://doi.org/10.1124/mol.110.066514

5 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20813864

https://syndication.highwire.org/content/doi/10.1124/mol.110.066514

5 July 2024

1 reference

Crossref

https://api.crossref.org/works/10.1124/MOL.110.066514

5 July 2024

published in

Molecular Pharmacology

1 reference

8 August 2017

volume

78

1 reference

8 August 2017

issue

6

1 reference

8 August 2017

page(s)

1072-1078

1 reference

HIF-1: upstream and downstream of cancer metabolism

8 August 2017

cites work

1 reference

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12 July 2018

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Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer

12 July 2018

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HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability

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Terpenoid tetrahydroisoquinoline alkaloids emetine, klugine, and isocephaeline inhibit the activation of hypoxia-inducible factor-1 in breast tumor cells

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Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.

12 July 2018

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Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors

12 July 2018

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Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells

12 July 2018

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Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice

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26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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inferred from PubMed ID database lookup

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based on heuristic

The aryl hydrocarbon receptor predisposes hepatocytes to Fas-mediated apoptosis

19

1 reference

Crossref

https://api.crossref.org/works/10.1124/MOL.110.066514

5 July 2024

Identifiers

1 reference

8 August 2017

1 reference

8 August 2017

1 reference