Organosulfur compounds from alliaceae in the prevention of human pathologies. (Q35784872)

10 August 2017

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title

Organosulfur compounds from alliaceae in the prevention of human pathologies (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361170&resulttype=core&format=json

13 May 2020

alliaceae

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2

Danyelle M Townsend

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361170&resulttype=core&format=json

13 May 2020

3

Kenneth D Tew

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361170&resulttype=core&format=json

13 May 2020

1

Haim Tapiero

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361170&resulttype=core&format=json

13 May 2020

language of work or name

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1 April 2004

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10 August 2017

11

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Biomedicine and Pharmacotherapy

inferred from page(s)

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361170&resulttype=core&format=json

13 May 2020

volume

58

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361170&resulttype=core&format=json

13 May 2020

issue

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361170&resulttype=core&format=json

13 May 2020

page(s)

183-193

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361170&resulttype=core&format=json

Increased acetylation of histones induced by diallyl disulfide and structurally related molecules

13 May 2020

cites work

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12 December 2020

Inhibition of carcinogen-induced activity of gamma-glutamyl transpeptidase by certain dietary constituents in mouse skin.

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12 December 2020

Inhibition of cholesterol biosynthesis by organosulfur compounds derived from garlic

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12 December 2020

Garlic for treating hypercholesterolemia. A meta-analysis of randomized clinical trials

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12 December 2020

Effects of allyl mercaptan and various allium-derived compounds on cholesterol synthesis and secretion in Hep-G2 cells

1 reference

12 December 2020

Alterations of prostate biomarker expression and testosterone utilization in human LNCaP prostatic carcinoma cells by garlic-derived S-allylmercaptocysteine

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12 December 2020

N alpha-(1-deoxy-D-fructos-1-yl)-L-arginine, an antioxidant compound identified in aged garlic extract

1 reference

12 December 2020

Aged garlic extract, a modulator of cardiovascular risk factors: a dose-finding study on the effects of AGE on platelet functions

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12 December 2020

The effects of aged garlic extract on lipid peroxidation and the deformability of erythrocytes

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12 December 2020

A historical perspective on garlic and cancer.

1 reference

12 December 2020

Garlic and cancer: a critical review of the epidemiologic literature

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12 December 2020

Mechanisms of inhibition of chemical toxicity and carcinogenesis by diallyl sulfide (DAS) and related compounds from garlic

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12 December 2020

Prevention of pathologies associated with oxidative stress and dietary intake deficiencies: folate deficiency and requirements

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12 December 2020

Folate, homocysteine, endothelial function and cardiovascular disease. What is the link?

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12 December 2020

Folate deficiency-induced oxidative stress and apoptosis are mediated via homocysteine-dependent overproduction of hydrogen peroxide and enhanced activation of NF-kappaB in human Hep G2 cells

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12 December 2020

Protein N-homocysteinylation: implications for atherosclerosis.

1 reference

12 December 2020

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells

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12 December 2020

The simultaneous generation of superoxide and nitric oxide can initiate lipid peroxidation in human low density lipoprotein

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12 December 2020

Spermidine/spermine N1-acetyltransferase, a new biochemical marker for epithelial proliferation in rat bladder

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12 December 2020

Tumor inhibition by a sulfhydryl-blocking agent related to an active principle of garlic (Allium sativum)

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12 December 2020

Inhibition of 7,12-dimethylbenz[a]anthracene-induced mammary tumors and DNA adducts by garlic powder

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12 December 2020

Mammary cancer prevention by regular garlic and selenium-enriched garlic

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12 December 2020

Identified diallyl polysulfides from an aged garlic extract which protects the membranes from lipid peroxidation

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12 December 2020

Modulation of N-nitrosomethylbenzylamine bioactivation by diallyl sulfide in vivo

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12 December 2020

Inhibitory effect of diet related sulphydryl compounds on the formation of carcinogenic nitrosamines

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12 December 2020

Inhibition of whole blood platelet-aggregation by compounds in garlic clove extracts and commercial garlic products

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12 December 2020

Inhibitory effects of diallyl sulfide on the metabolism and tumorigenicity of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A/J mouse lung.

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12 December 2020

Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity

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12 December 2020

Inhibition of cholesterol synthesis in vitro by extracts and isolated compounds prepared from garlic and wild garlic

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12 December 2020

Hepatitis B virus transactivator MHBst: activation of NF-kappa B, selective inhibition by antioxidants and integral membrane localization

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12 December 2020

Effect on active oxygen species of alliin and Allium sativum (garlic) powder

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12 December 2020

The pathogenesis of coronary artery disease and the acute coronary syndromes (1).

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12 December 2020

Isoprenoid modification and plasma membrane association: critical factors for ras oncogenicity

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12 December 2020

Inhibition of cytochrome P-450 2E1 by diallyl sulfide and its metabolites.

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12 December 2020

Effect of allixin, a phytoalexin produced by garlic, on mutagenesis, DNA-binding and metabolism of aflatoxin B1.

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12 December 2020

Garlic compounds modulate macrophage and T-lymphocyte functions

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12 December 2020

Evidence for direct coupling of primary agonist-receptor interaction to the exposure of functional IIb-IIIa complexes in human blood platelets. Results from studies with the antiplatelet compound ajoene

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12 December 2020

Allicin, a naturally occurring antibiotic from garlic, specifically inhibits acetyl-CoA synthetase.

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12 December 2020

Comparative studies of the effects of stilbene compounds on hepatic ornithine decarboxylase and S-adenosylmethionine decarboxylase induction in rats

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12 December 2020

Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aorta

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12 December 2020

Lipid peroxide and transition metals are required for the toxicity of oxidized low density lipoprotein to cultured endothelial cells

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12 December 2020

Free-radical processes in multistage carcinogenesis.

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12 December 2020

Probucol prevents oxidative injury to endothelial cells

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12 December 2020

Macrophages, endothelial cells, and lipoprotein oxidation in the pathogenesis of atherosclerosis

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12 December 2020

The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes

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12 December 2020

Universal control mechanism regulating onset of M-phase

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12 December 2020

Differentiating and growth inhibitory effects of diallyl disulfide on cancer cells.

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12 December 2020

Antiproliferative effects of garlic constituents in cultured human breast-cancer cells.

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12 December 2020

The cytotoxic effect of ajoene, a natural product from garlic, investigated with different cell lines

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12 December 2020

Identification and preliminary characterization of protein-cysteine farnesyltransferase

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12 December 2020

Chemopreventive action of garlic on methylcholanthrene-induced carcinogenesis in the uterine cervix of mice.

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12 December 2020

Anti-allergic effects of aged garlic extract

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12 December 2020

Immunomodulation and antitumor activities of Aged Garlic Extract

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12 December 2020

Chemoprevention of 1,2-dimethylhydrazine-induced colon cancer in mice by naturally occurring organosulfur compounds.

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12 December 2020

In vitro mechanism of inhibition of bacterial cell growth by allicin

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12 December 2020

Impaired endothelium-dependent relaxation to aggregating platelets and related vasoactive substances in porcine coronary arteries in hypercholesterolemia and atherosclerosis

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12 December 2020

Antitumor-promoting activity of garlic extracts

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12 December 2020

Vascular responses to leukocyte products in atherosclerotic primates

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12 December 2020

Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity

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12 December 2020

Inhibition of N-nitrosodiethylamine carcinogenesis in mice by naturally occurring organosulfur compounds and monoterpenes.

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12 December 2020

Allium vegetables and reduced risk of stomach cancer

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12 December 2020

Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor

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12 December 2020

Oxygen-derived free radicals, endothelium, and responsiveness of vascular smooth muscle

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12 December 2020

Evidence for the mechanism by which garlic inhibits platelet aggregation

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12 December 2020

Chemoprevention of N-nitrosomethylbenzylamine-induced esophageal cancer in rats by the naturally occurring thioether, diallyl sulfide.

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12 December 2020

Effect of dried garlic on blood coagulation, fibrinolysis, platelet aggregation and serum cholesterol levels in patients with hyperlipoproteinemia

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12 December 2020

Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate

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12 December 2020

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12 December 2020

Effects of organosulfur compounds from garlic and onions on benzo[a]pyrene-induced neoplasia and glutathione S-transferase activity in the mouse.

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12 December 2020

Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis

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12 December 2020

Effect of hypercholesterolemia on vascular reactivity in the rabbit. I. Endothelium-dependent and endothelium-independent contractions and relaxations in isolated arteries of control and hypercholesterolemic rabbits

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12 December 2020

Selective suppression of platelet thromboxane formation with sparing of vascular prostacyclin synthesis by aqueous extract of garlic in rabbits

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12 December 2020

Effects of garlic and onion oils on glutathione peroxidase activity, the ratio of reduced/oxidized glutathione and ornithine decarboxylase induction in isolated mouse epidermal cells treated with tumor promoters.

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12 December 2020

Monocytes and neutrophils oxidize low density lipoprotein making it cytotoxic

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12 December 2020

Serum cholesterol, lipoproteins, and the risk of coronary heart disease. The Framingham study

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12 December 2020

Garlic as a platelet inhibitor

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12 December 2020

Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins

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12 December 2020

Enhanced macrophage degradation of biologically modified low density lipoprotein.

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12 December 2020

Suppression of avian hepatic lipid metabolism by solvent extracts of garlic: impact on serum lipids.

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12 December 2020

Effects of garlic on lipid metabolism in rats fed cholesterol or lard

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12 December 2020

Effect of garlic on human platelet aggregation in vitro

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12 December 2020

The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions

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12 December 2020

Thioallyl compounds: potent inhibitors of cell proliferation

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12 December 2020

Potent activation of nitric oxide synthase by garlic: a basis for its therapeutic applications

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12 December 2020

Molecular mechanisms and therapeutic strategies related to nitric oxide.

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12 December 2020

Activation of 2-aminofluorene by prostaglandin endoperoxide H synthase-2

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12 December 2020

Efficacy of cancer prevention by high-selenium garlic is primarily dependent on the action of selenium

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12 December 2020

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12 December 2020

Relationship between cytochrome P450 2E1 and acetone catabolism in rats as studied with diallyl sulfide as an inhibitor

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12 December 2020

The effect of cholesterol-lowering and antioxidant therapy on endothelium-dependent coronary vasomotion

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12 December 2020

Principles of CDK regulation

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12 December 2020

Atherogenic levels of low density lipoprotein alter the permeability and composition of the endothelial barrier

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12 December 2020

A garlic derivative, ajoene, inhibits platelet deposition on severely damaged vessel wall in an in vivo porcine experimental model

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12 December 2020

Antioxidant and radical scavenging effects of aged garlic extract and its constituents

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12 December 2020

Cell cycle control and cancer

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12 December 2020

Oxidized lipoproteins in atherosclerosis and thrombosis

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12 December 2020

Receptors for ADP on human blood platelets.

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12 December 2020

Low-dose alpha-tocopherol improves and high-dose alpha-tocopherol worsens endothelial vasodilator function in cholesterol-fed rabbits.

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12 December 2020

Vitamin E protects against impairment of endothelium-mediated relaxations in cholesterol-fed rabbits

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12 December 2020

Molecular mechanisms in cancer induction and prevention

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12 December 2020

Garlic reduces plasma lipids by inhibiting hepatic cholesterol and triacylglycerol synthesis.

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12 December 2020

Effect of mutations at active site residues on the activity of ornithine decarboxylase and its inhibition by active site-directed irreversible inhibitors.

1 reference

12 December 2020

Free radicals in the genesis of Alzheimer's disease

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12 December 2020

Free radicals in disease processes: a compilation of cause and consequence

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12 December 2020

Impact of organosulfur compounds in garlic on canine mammary tumor cells in culture.

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12 December 2020

Vegetables, fruit, and colon cancer in the Iowa Women's Health Study.

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12 December 2020

A garlic extract protects from ultraviolet B (280-320 nm) radiation-induced suppression of contact hypersensitivity

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12 December 2020

Dietary garlic suppresses DNA adducts caused by N-nitroso compounds

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12 December 2020

Garlic supplementation and lipoprotein oxidation susceptibility

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12 December 2020

Chemoprevention of colon carcinogenesis by organosulfur compounds.

1 reference

12 December 2020

Impact of various sources of garlic and their constituents on 7,12-dimethylbenz[a]anthracene binding to mammary cell DNA.

1 reference

12 December 2020

Effect of garlic on total serum cholesterol. A meta-analysis

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12 December 2020

Multiple inhibitory effects of garlic extracts on cholesterol biosynthesis in hepatocytes

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12 December 2020

A protein fraction from aged garlic extract enhances cytotoxicity and proliferation of human lymphocytes mediated by interleukin-2 and concanavalin A

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12 December 2020

Growth inhibition and modulation of cell markers of melanoma by S-allyl cysteine.

1 reference

12 December 2020

A modern view of atherogenesis

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12 December 2020

The inducible transcription factor NF-kappa B: structure-function relationship of its protein subunits

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12 December 2020

Effects of a dried garlic preparation on fibrinolysis and platelet aggregation in healthy subjects

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12 December 2020

The pathogenesis of atherosclerosis: a perspective for the 1990s

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12 December 2020

Signal transduction. How receptors turn Ras on.

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12 December 2020

Transcriptional activation of cytochrome P450 2B1/2 genes in rat liver by diallyl sulfide, a compound derived from garlic

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12 December 2020

Inhibition of NF-kappa B activation in human T-cell lines by anetholdithiolthione

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12 December 2020

Diallyl disulfide suppresses the growth of human colon tumor cell xenografts in athymic nude mice

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12 December 2020

Antioxidant and redox regulation of gene transcription

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12 December 2020

Prevention by alpha-tocopherol and rutin of glutathione and ATP depletion induced by oxidized LDL in cultured endothelial cells

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12 December 2020

Chemopreventive effect of S-allylcysteine and its relationship to the detoxification enzyme glutathione S-transferase.

1 reference

12 December 2020

Effects of oxidized low-density lipoprotein on vascular contraction and relaxation: clinical and pharmacological implications in atherosclerosis

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12 December 2020

Bcl-2 down-regulates the activity of transcription factor NF-kappaB induced upon apoptosis

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12 December 2020

The role of oxidized lipoproteins in atherogenesis

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12 December 2020

Novel anti-carcinogenic activity of an organosulfide from garlic: inhibition of H-RAS oncogene transformed tumor growth in vivo by diallyl disulfide is associated with inhibition of p21H-ras processing

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12 December 2020

The pathogenesis of cardiovascular disease: role of the endothelium as a target and mediator

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12 December 2020

Inhibition of aflatoxin B1- and N-nitrosodiethylamine-induced liver preneoplastic foci in rats fed naturally occurring allyl sulfides.

1 reference

12 December 2020

Aged garlic extract prolongs longevity and improves spatial memory deficit in senescence-accelerated mouse.

1 reference

12 December 2020

A double-blind crossover study in moderately hypercholesterolemic men that compared the effect of aged garlic extract and placebo administration on blood lipids

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12 December 2020

Effect of garlic and fish-oil supplementation on serum lipid and lipoprotein concentrations in hypercholesterolemic men.

1 reference

12 December 2020

Metabolism of the chemoprotective agent diallyl sulfide to glutathione conjugates in rats.

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12 December 2020

Garlic: its anticarcinogenic and antitumorigenic properties.

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12 December 2020

Effect of essential oil of garlic on serum fibrinolytic activity in patients with coronary artery disease

1 reference

12 December 2020

Helicobacter pylori--in vitro susceptibility to garlic (Allium sativum) extract

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12 December 2020

S-allylmercaptocysteine inhibits cell proliferation and reduces the viability of erythroleukemia, breast, and prostate cancer cell lines.

1 reference

12 December 2020

Glutathione S-transferases of female A/J mouse lung and their induction by anticarcinogenic organosulfides from garlic.

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12 December 2020

Homocysteine, oxidative stress, and vascular disease

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12 December 2020

S-allyl cysteine inhibits activation of nuclear factor kappa B in human T cells

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12 December 2020

S-allyl cysteine inhibits nitrosomorpholine formation and bioactivation.

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12 December 2020

Aged garlic extract and its constituents inhibit Cu(2+)-induced oxidative modification of low density lipoprotein

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12 December 2020

The effect of the aged garlic extract, 'Kyolic', on the development of experimental atherosclerosis

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12 December 2020

Effects of garlic thioallyl derivatives on growth, glutathione concentration, and polyamine formation of human prostate carcinoma cells in culture

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12 December 2020

S-allylmercaptocysteine, a stable thioallyl compound, induces apoptosis in erythroleukemia cell lines

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12 December 2020

Effect of food products on endogenous generation of N-nitrosamines in rats

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12 December 2020

Garlic compounds protect vascular endothelial cells from oxidized low density lipoprotein-induced injury

1 reference

12 December 2020

Mechanism of action of dietary chemoprotective agents in rat liver: induction of phase I and II drug metabolizing enzymes and aflatoxin B1 metabolism

1 reference

12 December 2020

Twelve-year results of the Coronary Risk Factor Study (CORIS).

1 reference

12 December 2020

Induction of glutathione S-transferase pi as a bioassay for the evaluation of potency of inhibitors of benzo(a)pyrene-induced cancer in a murine model.

1 reference

12 December 2020

Cigarette Smoking and Progression of Atherosclerosis

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12 December 2020

Modification of hepatic drug-metabolizing enzymes in rats treated with alkyl sulfides.

1 reference

12 December 2020

Ajoene, a compound of garlic, induces apoptosis in human promyeloleukemic cells, accompanied by generation of reactive oxygen species and activation of nuclear factor kappaB

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12 December 2020

Initial study on naturally occurring products from traditional Chinese herbs and vegetables for chemoprevention.

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12 December 2020

Depressed p34cdc2 kinase activity and G2/M phase arrest induced by diallyl disulfide in HCT-15 cells.

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12 December 2020

Changes in platelet function and susceptibility of lipoproteins to oxidation associated with administration of aged garlic extract

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12 December 2020

Effect of garlic (Allium sativum) on blood lipids, blood sugar, fibrinogen and fibrinolytic activity in patients with coronary artery disease.

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12 December 2020

Inhibitors of lipoxygenase: a new class of cancer chemopreventive agents.

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12 December 2020

Homocysteine and cardiovascular disease.

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12 December 2020

Physical activity, physical fitness, and risk of dying.

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12 December 2020

Nitric oxide in atherosclerosis: vascular protector or villain?

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12 December 2020

Prevention of liver damage by aged garlic extract and its components in mice

1 reference

COCI

https://opencitations.net/index/api/v1/citations/10.1002/PTR.2650030203

10.1016/J.BIOPHA.2004.01.004

10 April 2024

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361170&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361170&resulttype=core&format=json

13 May 2020

1 reference