Telomere biology: integrating chromosomal end protection with DNA damage response (Q36103575)

12 August 2017

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title

Telomere biology: integrating chromosomal end protection with DNA damage response (English)

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12 August 2017

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Predrag Slijepcevic

1

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12 August 2017

Suliman Al-Wahiby

series ordinal

2

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12 August 2017

publication date

1 September 2005

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12 August 2017

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12 August 2017

volume

114

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12 August 2017

issue

4

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12 August 2017

page(s)

275-285

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ERCC4 (XPF) encodes a human nucleotide excision repair protein with eukaryotic recombination homologs

12 August 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FS00412-005-0338-4

Alternative lengthening of telomeres in mammalian cells

21 January 2018

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12 December 2020

Breaks at telomeres and TRF2-independent end fusions in Fanconi anemia

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12 December 2020

Nonhomologous end joining and V(D)J recombination require an additional factor

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12 December 2020

A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena

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12 December 2020

DNA double strand break repair in mammalian cells

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12 December 2020

Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs

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12 December 2020

The Stability of Broken Ends of Chromosomes in Zea Mays.

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12 December 2020

TRF1 is a critical trans-acting factor required for de novo telomere formation in human cells

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12 December 2020

Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation

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12 December 2020

Telomere dysfunction: a potential cancer predisposition factor.

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12 December 2020

The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang.

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12 December 2020

Association between telomere length in blood and mortality in people aged 60 years or older

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12 December 2020

Human telomeric protein TRF2 associates with genomic double-strand breaks as an early response to DNA damage.

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12 December 2020

Regulation of the human telomerase reverse transcriptase gene

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12 December 2020

Telomere length deregulation and enhanced sensitivity to genotoxic stress in Arabidopsis mutants deficient in Ku70.

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12 December 2020

Recombination in telomere-length maintenance

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12 December 2020

Accelerated telomere shortening and telomere abnormalities in radiosensitive cell lines

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12 December 2020

Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability

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12 December 2020

Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang

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12 December 2020

Telomerase is not an oncogene

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12 December 2020

Assembly of functional ALT-associated promyelocytic leukemia bodies requires Nijmegen Breakage Syndrome 1

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12 December 2020

Telomere protection without a telomerase; the role of ATM and Mre11 in Drosophila telomere maintenance

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12 December 2020

DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2

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12 December 2020

Ku acts in a unique way at the mammalian telomere to prevent end joining

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12 December 2020

Alternative lengthening of telomeres is characterized by high rates of telomeric exchange.

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12 December 2020

Elongated Telomeres inscidMice

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12 December 2020

Healing of broken human chromosomes by the addition of telomeric repeats

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12 December 2020

Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse

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12 December 2020

Short telomeres result in organismal hypersensitivity to ionizing radiation in mammals

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12 December 2020

ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes

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12 December 2020

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

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12 December 2020

Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance

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12 December 2020

DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes

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12 December 2020

The DNA-dependent protein kinase

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12 December 2020

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

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12 December 2020

The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations

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12 December 2020

A truncated human chromosome 16 associated with α thalassaemia is stabilized by addition of telomeric repeat (TTAGGG)n

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12 December 2020

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

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12 December 2020

Upregulation of telomerase activity by X-irradiation in mouse leukaemia cells is independent of Tert, Terc, Tnks and Myc transcription

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12 December 2020

Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse

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12 December 2020

Impaired nuclear localization of defective DNA helicases in Werner's syndrome

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12 December 2020

Accelerated telomere shortening in response to life stress

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12 December 2020

Molecular genetics of Bloom's syndrome

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12 December 2020

The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response

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12 December 2020

A DNA damage checkpoint response in telomere-initiated senescence

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12 December 2020

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

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12 December 2020

Functional interaction between poly(ADP-Ribose) polymerase 2 (PARP-2) and TRF2: PARP activity negatively regulates TRF2.

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12 December 2020

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12 December 2020

Distribution of non-telomeric sites of the (TTAGGG)n telomeric sequence in vertebrate chromosomes

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12 December 2020

Telomere length measurement in mouse chromosomes by a modified Q-FISH method

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12 December 2020

Functional interaction between DNA-PKcs and telomerase in telomere length maintenance

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12 December 2020

A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells

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12 December 2020

Homologous recombination generates T-loop-sized deletions at human telomeres

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12 December 2020

Role of human Ku86 in telomere length maintenance and telomere capping

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12 December 2020

Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence

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12 December 2020

Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit

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12 December 2020

DNA damage and repair in telomeres: relation to aging

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12 December 2020

Protection of mammalian telomeres

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12 December 2020

New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin

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12 December 2020

Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres

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12 December 2020

Strand-Specific Postreplicative Processing of Mammalian Telomeres

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12 December 2020

Telomere length, chromatin structure and chromosome fusigenic potential

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12 December 2020

DNA damage foci at dysfunctional telomeres

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12 December 2020

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

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12 December 2020

Telomere length abnormalities in mammalian radiosensitive cells

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12 December 2020

Telomerase activity during the cell cycle and in gamma-irradiated hematopoietic cells

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12 December 2020

Normal telomere length and chromosomal end capping in poly(ADP-ribose) polymerase-deficient mice and primary cells despite increased chromosomal instability

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12 December 2020

New telomeres in yeast are initiated with a highly selected subset of TG1-3 repeats

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12 December 2020

Ku is associated with the telomere in mammals

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12 December 2020

The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease

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12 December 2020

Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells

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12 December 2020

Human Ku70 interacts with heterochromatin protein 1alpha

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12 December 2020

A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes

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12 December 2020

The Drosophila Mre11/Rad50 complex is required to prevent both telomeric fusion and chromosome breakage.

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12 December 2020

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

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12 December 2020

Molecular mechanisms of DNA double strand break repair

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12 December 2020

Telomere dynamics in Fancg-deficient mouse and human cells

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12 December 2020

Regulation of telomere length and suppression of genomic instability in human somatic cells by Ku86

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12 December 2020

Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases

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12 December 2020

Induction of telomerase activity by irradiation in human lymphoblasts

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12 December 2020

Accelerated telomere shortening in ataxia telangiectasia

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12 December 2020

Extra-chromosomal telomeric DNA in cells from Atm-/- mice and patients with ataxia-telangiectasia

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12 December 2020

Accelerated telomere shortening in Fanconi anemia fibroblasts--a longitudinal study

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12 December 2020

Chromosomal aberrations involving telomeres in BRCA1 deficient human and mouse cell lines

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12 December 2020

Localization of hRad9, hHus1, hRad1, and hRad17 and caffeine-sensitive DNA replication at the alternative lengthening of telomeres-associated promyelocytic leukemia body

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12 December 2020

Cloning of two new human helicase genes of the RecQ family: biological significance of multiple species in higher eukaryotes

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12 December 2020

Frequent recombination in telomeric DNA may extend the proliferative life of telomerase-negative cells

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12 December 2020

Telomere maintenance requires the RAD51D recombination/repair protein

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12 December 2020

Role of mammalian Rad54 in telomere length maintenance

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12 December 2020

10.1007/S00412-005-0338-4

Identifiers

DOI

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12 August 2017

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