SENP7 Potentiates cGAS Activation by Relieving SUMO-Mediated Inhibition of Cytosolic DNA Sensing (Q36251447)

13 August 2017

SENP7 Potentiates cGAS Activation by Relieving SUMO-Mediated Inhibition of Cytosolic DNA Sensing (English)

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13 August 2017

Ye Cui

1

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13 August 2017

Huansha Yu

2

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13 August 2017

Xin Zheng

3

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13 August 2017

Rui Peng

4

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13 August 2017

Qiang Wang

5

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13 August 2017

Yi Zhou

6

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13 August 2017

Rui Wang

7

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13 August 2017

Jiehua Wang

8

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13 August 2017

Bo Qu

9

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13 August 2017

Nan Shen

10

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13 August 2017

Qiang Guo

11

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13 August 2017

Xing Liu

12

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13 August 2017

Chen Wang

13

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13 August 2017

17 January 2017

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13 August 2017

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13 August 2017

13

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13 August 2017

1

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13 August 2017

e1006156

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Creative Commons Attribution 4.0 International

13 August 2017

start time

17 January 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Sumoylation Promotes the Stability of the DNA Sensor cGAS and the Adaptor STING to Regulate the Kinetics of Response to DNA Virus

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ER Adaptor SCAP Translocates and Recruits IRF3 to Perinuclear Microsome Induced by Cytosolic Microbial DNAs

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1 October 2017

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STING: infection, inflammation and cancer

1 October 2017

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1 October 2017

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1 October 2017

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Transmission of innate immune signaling by packaging of cGAMP in viral particles

1 October 2017

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Cytosolic sensing of aberrant DNA: arming STING on the endoplasmic reticulum

1 October 2017

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Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1.

1 October 2017

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Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis

1 October 2017

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The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

1 October 2017

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Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity

1 October 2017

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Sensing and responding to cytosolic viruses invasions: An orchestra of kaleidoscopic ubiquitinations

1 October 2017

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STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors.

1 October 2017

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STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.

1 October 2017

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Self-DNA, STING-dependent signaling and the origins of autoinflammatory disease

1 October 2017

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RNF26 temporally regulates virus-triggered type I interferon induction by two distinct mechanisms

1 October 2017

1 reference

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The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop

1 October 2017

1 reference

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Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization

1 October 2017

1 reference

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cGAS dimerization entangles DNA recognition

1 October 2017

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Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP.

1 October 2017

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Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects

1 October 2017

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Dynamic regulation of innate immunity by ubiquitin and ubiquitin-like proteins

1 October 2017

1 reference

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Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

Negative regulation of TLR inflammatory signaling by the SUMO-deconjugating enzyme SENP6

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.

1 October 2017

1 reference

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The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING

1 October 2017

1 reference

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Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity

1 October 2017

1 reference

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Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

1 October 2017

1 reference

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Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

Function and regulation of SUMO proteases

1 October 2017

1 reference

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STING manifests self DNA-dependent inflammatory disease

1 October 2017

1 reference

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The small ubiquitin-like modifier-deconjugating enzyme sentrin-specific peptidase 1 switches IFN regulatory factor 8 from a repressor to an activator during macrophage activation

1 October 2017

1 reference

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SENP2 negatively regulates cellular antiviral response by deSUMOylating IRF3 and conditioning it for ubiquitination and degradation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

Mitochondrial ubiquitin ligase MARCH5 promotes TLR7 signaling by attenuating TANK action

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

Herc5 attenuates influenza A virus by catalyzing ISGylation of viral NS1 protein

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

Positive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modification

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

SUMOylation and De-SUMOylation: wrestling with life's processes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

Modification in reverse: the SUMO proteases

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

Association of increased interferon-inducible gene expression with disease activity and lupus nephritis in patients with systemic lupus erythematosus

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

The 1982 revised criteria for the classification of systemic lupus erythematosus

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

The E3 ubiquitin ligase AMFR and INSIG1 bridge the activation of TBK1 kinase by modifying the adaptor STING.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

Dnase2a deficiency uncovers lysosomal clearance of damaged nuclear DNA via autophagy

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

TCR-induced sumoylation of the kinase PKC-θ controls T cell synapse organization and T cell activation.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

Mycobacterium tuberculosis Meets the Cytosol: The Role of cGAS in Anti-mycobacterial Immunity.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

Spreading depression triggers headache by activating neuronal Panx1 channels

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

Characterization of SENP7, a SUMO-2/3-specific isopeptidase

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

Induction of IRF-3/-7 kinase and NF-kappaB in response to double-stranded RNA and virus infection: common and unique pathways

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5271409

10.1371/JOURNAL.PPAT.1006156

22 September 2018

Identifiers

DOI

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release_a3hsgpziqzbstcka4jfh3lzfbi

13 August 2017

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Fatcat

https://api.fatcat.wiki/v0/release/a3hsgpziqzbstcka4jfh3lzfbi

mapped directly with Wikidata item

24 November 2022

based on heuristic

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13 August 2017

1 reference