mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy (Q36435405)

14 August 2017

mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy (English)

1 reference

ubiquitin-proteasome system

14 August 2017

0 references

0 references

3

Steven P Gygi

1 reference

14 August 2017

Jinghui Zhao

1

1 reference

14 August 2017

Bo Zhai

series ordinal

2

1 reference

14 August 2017

Alfred Lewis Goldberg

series ordinal

4

1 reference

14 August 2017

language of work or name

English

0 references

publication date

15 December 2015

1 reference

Proceedings of the National Academy of Sciences of the United States of America

14 August 2017

1 reference

14 August 2017

112

1 reference

14 August 2017

52

1 reference

14 August 2017

15790-15797

1 reference

describes a project that uses

14 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4703015/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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30 September 2017

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Ubiquitin-Dependent And Independent Signals In Selective Autophagy

30 September 2017

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Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome

30 September 2017

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Regulation of mTORC1 by PI3K signaling

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30 September 2017

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30 September 2017

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Coordinated regulation of protein synthesis and degradation by mTORC1

30 September 2017

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Making new contacts: the mTOR network in metabolism and signalling crosstalk

30 September 2017

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IGF-1 receptor antagonism inhibits autophagy

30 September 2017

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30 September 2017

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Ubiquitylation by Trim32 causes coupled loss of desmin, Z-bands, and thin filaments in muscle atrophy

30 September 2017

1 reference

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A unifying model for mTORC1-mediated regulation of mRNA translation.

30 September 2017

1 reference

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Mechanistic studies of substrate-assisted inhibition of ubiquitin-activating enzyme by adenosine sulfamate analogues

30 September 2017

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The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile.

30 September 2017

1 reference

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mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway

30 September 2017

1 reference

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Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling

30 September 2017

1 reference

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The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.

30 September 2017

1 reference

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Global quantification of mammalian gene expression control

30 September 2017

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Expression of α-taxilin in hepatocellular carcinoma correlates with growth activity and malignant potential of the tumor.

30 September 2017

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Activation of a metabolic gene regulatory network downstream of mTOR complex 1

30 September 2017

1 reference

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30 September 2017

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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

30 September 2017

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Histone acetyltransferase Hbo1: catalytic activity, cellular abundance, and links to primary cancers

30 September 2017

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Immunoregulatory functions of mTOR inhibition.

30 September 2017

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An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

30 September 2017

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Molecular mechanisms of mTOR-mediated translational control

30 September 2017

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An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

30 September 2017

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SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

30 September 2017

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Rapid turnover of the mTOR complex 1 (mTORC1) repressor REDD1 and activation of mTORC1 signaling following inhibition of protein synthesis

30 September 2017

1 reference

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FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells

30 September 2017

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FoxO3 controls autophagy in skeletal muscle in vivo

30 September 2017

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Functions of the proteasome: from protein degradation and immune surveillance to cancer therapy

30 September 2017

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The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

30 September 2017

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Proteasome inhibitors: from research tools to drug candidates

30 September 2017

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Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703015

Regulation of the mevalonate pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703015

Intracellular protein degradation in mammalian and bacterial cells: Part 2

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703015

Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703015

Expression of α-taxilin in the murine gastrointestinal tract: potential implication in cell proliferation

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703015

Proteasomes. A molecular census of 26S proteasomes in intact neurons.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703015

The pharmacology of mTOR inhibition

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703015

Genetic alterations and oncogenic pathways associated with breast cancer subtypes

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703015

Developmental and spatial expression pattern of alpha-taxilin in the rat central nervous system

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703015

Control of proteasomal proteolysis by mTOR

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1521919112

Increased alpha-taxilin protein expression is associated with the metastatic and invasive potential of renal cell cancer

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26669439

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1521919112

1 reference

14 August 2017

0 references

1 reference

14 August 2017

1 reference