The clinical applications of genome editing in HIV. (Q36942032)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27053530%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

title

The clinical applications of genome editing in HIV (English)

1 reference

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31 March 2020

1

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31 March 2020

author name string

Paula M Cannon

series ordinal

2

1 reference

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31 March 2020

language of work or name

English

0 references

publication date

6 April 2016

1 reference

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31 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27053530%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

volume

127

1 reference

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31 March 2020

issue

21

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31 March 2020

page(s)

2546-2552

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Identification of novel HIV-1 dependency factors in primary CCR4(+)CCR6(+)Th17 cells via a genome-wide transcriptional approach

31 March 2020

cites work

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Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template

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29 September 2017

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29 September 2017

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29 September 2017

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Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV

29 September 2017

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Simultaneous zinc-finger nuclease editing of the HIV coreceptors ccr5 and cxcr4 protects CD4+ T cells from HIV-1 infection.

29 September 2017

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Pre-clinical modeling of CCR5 knockout in human hematopoietic stem cells by zinc finger nucleases using humanized mice

29 September 2017

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29 September 2017

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Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells

29 September 2017

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ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

29 September 2017

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Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases

29 September 2017

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Long-term reduction in peripheral blood HIV type 1 reservoirs following reduced-intensity conditioning allogeneic stem cell transplantation

29 September 2017

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Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5

29 September 2017

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29 September 2017

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29 September 2017

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Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase.

29 September 2017

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HIV Restriction Factors and Mechanisms of Evasion

29 September 2017

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Zinc-finger nuclease editing of human cxcr4 promotes HIV-1 CD4(+) T cell resistance and enrichment

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Genotoxicity of retroviral hematopoietic stem cell gene therapy

29 September 2017

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Chemokine receptor 5 knockout strategies

29 September 2017

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Evidence for the cure of HIV infection by CCR5Δ32/Δ32 stem cell transplantation

29 September 2017

1 reference

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Genetic Associations of Variants in Genes Encoding HIV‐Dependency Factors Required for HIV‐1 Infection

29 September 2017

1 reference

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Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

29 September 2017

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RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma

29 September 2017

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Mutation of a single residue renders human tetherin resistant to HIV-1 Vpu-mediated depletion

29 September 2017

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Hematopoietic and endothelial differentiation of human induced pluripotent stem cells

29 September 2017

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Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells

29 September 2017

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Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation

29 September 2017

1 reference

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Incomplete peripheral CD4+ cell count restoration in HIV-infected patients receiving long-term antiretroviral treatment

29 September 2017

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Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

29 September 2017

1 reference

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Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

29 September 2017

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The epidemiology of HIV coreceptor tropism.

29 September 2017

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A whole-genome association study of major determinants for host control of HIV-1

29 September 2017

1 reference

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HIV-1 proviral DNA excision using an evolved recombinase

29 September 2017

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Gene transfer in humans using a conditionally replicating lentiviral vector

29 September 2017

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Genotoxicity of retroviral integration in hematopoietic cells.

29 September 2017

1 reference

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HIV-1 resistance conferred by siRNA cosuppression of CXCR4 and CCR5 coreceptors by a bispecific lentiviral vector

29 September 2017

1 reference

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Highly efficient endogenous human gene correction using designed zinc-finger nucleases

29 September 2017

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A single amino acid change in the SPRY domain of human Trim5alpha leads to HIV-1 restriction

29 September 2017

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Protecting from R5-tropic HIV: individual and combined effectiveness of a hammerhead ribozyme and a single-chain Fv antibody that targets CCR5.

29 September 2017

1 reference

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Conservative homologous recombination preferentially repairs DNA double-strand breaks in the S phase of the cell cycle in human cells

29 September 2017

1 reference

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A single amino acid substitution in human APOBEC3G antiretroviral enzyme confers resistance to HIV-1 virion infectivity factor-induced depletion

29 September 2017

1 reference

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In vivo selection of MGMT(P140K) lentivirus–transduced human NOD/SCID repopulating cells without pretransplant irradiation conditioning

29 September 2017

1 reference

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Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5.

29 September 2017

1 reference

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Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

29 September 2017

1 reference

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Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy

29 September 2017

1 reference

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Phenotypic knockout of HIV type 1 chemokine coreceptor CCR-5 by intrakines as potential therapeutic approach for HIV-1 infection

29 September 2017

1 reference

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Homing endonucleases: keeping the house in order

29 September 2017

1 reference

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Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection

29 September 2017

1 reference

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Change in coreceptor use correlates with disease progression in HIV-1--infected individuals

29 September 2017

1 reference

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Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

29 September 2017

1 reference

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Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4882804

Genome editing technologies: defining a path to clinic

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4882804

Targeted genome editing in human repopulating haematopoietic stem cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4882804

Off-target-free gene delivery by affinity-purified receptor-targeted viral vectors

27 June 2018

1 reference

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HIV eradication--from Berlin to Boston

4 September 2018

1 reference

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Preferential survival of CD4+ T lymphocytes engineered with anti-human immunodeficiency virus (HIV) genes in HIV-infected individuals

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4882804

Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4882804

Selective survival of peripheral blood lymphocytes in children with HIV-1 following delivery of an anti-HIV gene to bone marrow CD34(+) cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4882804

In vivo selection for human and murine hematopoietic cells transduced with a therapeutic MGMT lentiviral vector that inhibits HIV replication

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4882804

Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4882804

Characterization of anti-CCR5 ribozyme-transduced CD34+ hematopoietic progenitor cells in vitro and in a SCID-hu mouse model in vivo

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4882804

The role of a mutant CCR5 allele in HIV-1 transmission and disease progression.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4882804

Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27053530

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CCR2 chemokine receptor and AIDS progression

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27053530

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2016-01-678144

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27053530%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27053530%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

PubMed publication ID

27053530

1 reference