Novel strategies for Alzheimer's disease treatment (Q37012066)

17 August 2017

1 reference

title

Novel strategies for Alzheimer's disease treatment (English)

1 reference

17 August 2017

0 references

2

Edward Rockenstein

1 reference

17 August 2017

4

Robert Marr

1 reference

17 August 2017

5

Eliezer Masliah

1 reference

author name string

Brian Spencer

series ordinal

1

1 reference

17 August 2017

Leslie Crews

series ordinal

3

1 reference

17 August 2017

language of work or name

English

0 references

publication date

1 December 2007

1 reference

Expert Opinion on Biological Therapy

17 August 2017

published in

1 reference

17 August 2017

volume

7

1 reference

17 August 2017

issue

12

1 reference

17 August 2017

page(s)

1853-1867

1 reference

APOE genotype effects on Alzheimer's disease onset and epidemiology

17 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Occurrence of neuropil threads in the senile human brain and in Alzheimer's disease: a third location of paired helical filaments outside of neurofibrillary tangles and neuritic plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Relationship between plaques, tangles, and dystrophic processes in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

The molecular pathology of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Cycles of aberrant synaptic sprouting and neurodegeneration in Alzheimer's and dementia with Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Alzheimer's disease is a laminar, regional, and neural system specific disease, not a global brain disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

APP processing and synaptic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Translating cell biology into therapeutic advances in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Purification and cloning of amyloid precursor protein beta-secretase from human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

A novel protein, amyloid precursor-like protein 2, is present in human brain, cerebrospinal fluid and conditioned media

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Reconstitution of gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

The role of presenilin cofactors in the gamma-secretase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Presenilin 1 controls gamma-secretase processing of amyloid precursor protein in pre-golgi compartments of hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

ADAMs family members as amyloid precursor protein alpha-secretases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Structure and functions of the human amyloid precursor protein: the whole is more than the sum of its parts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

The search for alpha-secretase and its potential as a therapeutic approach to Alzheimer s disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Structural correlates of cognition in dementia: quantification and assessment of synapse change.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Synaptic pathology in Alzheimer's disease: a review of ultrastructural studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Functional neurogenesis in the adult hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Multipotent progenitor cells in the adult dentate gyrus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Increased hippocampal neurogenesis in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Increased proliferation reflects glial and vascular-associated changes, but not neurogenesis in the presenile Alzheimer hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Oligomers on the brain: the emerging role of soluble protein aggregates in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Common mechanisms of amyloid oligomer pathogenesis in degenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Vulnerability of synaptosomes from apoE knock-out mice to structural and oxidative modifications induced by A beta(1-40): implications for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid beta-peptide (1-42) in a transgenic Caenorhabditis elegans model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Rapid induction of Alzheimer A beta amyloid formation by zinc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

The lysosomal system in neurons. Involvement at multiple stages of Alzheimer's disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Pathways by which Abeta facilitates tau pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Metabolic regulation of brain Abeta by neprilysin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

The genetics and molecular pathology of Alzheimer's disease: roles of amyloid and the presenilins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Human neprilysin is capable of degrading amyloid beta peptide not only in the monomeric form but also the pathological oligomeric form

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Neprilysin-sensitive synapse-associated amyloid-beta peptide oligomers impair neuronal plasticity and cognitive function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Immunohistochemical localization of neprilysin in the human cerebral cortex: inverse association with vulnerability to amyloid beta-protein (Abeta) deposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Age- and region-dependent alterations in Abeta-degrading enzymes: implications for Abeta-induced disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Neprilysin content is reduced in Alzheimer brain areas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Reduced neprilysin in high plaque areas of Alzheimer brain: a possible relationship to deficient degradation of beta-amyloid peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Relationship between beta amyloid peptide generating molecules and neprilysin in Alzheimer disease and normal brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Dinucleotide repeat polymorphisms in the neprilysin gene are not associated with sporadic Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Lack of association of neprilysin polymorphism with Alzheimer's disease and Alzheimer's disease-type neuropathological changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Possible increased risk for Alzheimer's disease associated with neprilysin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Association of the Neprilysin gene with susceptibility to late-onset Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Mutation screening and association study of the neprilysin gene in sporadic Alzheimer's disease in Chinese persons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Polymorphisms in neprilysin gene affect the risk of Alzheimer's disease in Finnish patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

A nontransgenic mouse model shows inducible amyloid-beta (Abeta) peptide deposition and elucidates the role of apolipoprotein E in the amyloid cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Presynaptic localization of neprilysin contributes to efficient clearance of amyloid-beta peptide in mouse brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Herpes simplex virus RNAi and neprilysin gene transfer vectors reduce accumulation of Alzheimer's disease-related amyloid-beta peptide in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Abeta 42-induced increase in neprilysin is associated with prevention of amyloid plaque formation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Anti-amyloid activity of neprilysin in plaque-bearing mouse models of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Cholinergic and glutamatergic drugs in Alzheimer's disease therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Clinical predictors of progression to Alzheimer disease in amnestic mild cognitive impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

A 24-week randomized, controlled trial of memantine in patients with moderate-to-severe Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

A lipid boundary separates APP and secretases and limits amyloid beta-peptide generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

The neuroprotective effects of Cerebrolysin in a transgenic model of Alzheimer's disease are associated with improved behavioral performance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

A potential role of the curry spice curcumin in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

The molecular basis of memantine action in Alzheimer's disease and other neurologic disorders: low-affinity, uncompetitive antagonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Towards safe, non-viral therapeutic gene expression in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Gene therapy with viral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Translational considerations for CNS gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Role of neurotrophic factors in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

APOE is a major susceptibility gene for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Gene delivery of human apolipoprotein E alters brain Abeta burden in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

A synthetic peptide blocking the apolipoprotein E/beta-amyloid binding mitigates beta-amyloid toxicity and fibril formation in vitro and reduces beta-amyloid plaques in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Decreased expression and activity of neprilysin in Alzheimer disease are associated with cerebral amyloid angiopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Neprylisin decreases uniformly in Alzheimer's disease and in normal aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Neuronal neprilysin overexpression is associated with attenuation of Abeta-related spatial memory deficit

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Neprilysin regulates amyloid Beta peptide levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Targeted delivery of proteins across the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Shortfalls in the peptidyl-prolyl cis-trans isomerase protein Pin1 in neurons are associated with frontotemporal dementias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Beta-amyloid precursor protein is a direct cleavage target of HtrA2 serine protease. Implications for the physiological function of HtrA2 in the mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Design and cloning of lentiviral vectors expressing small interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Unraveling in vivo functions of amyloid precursor protein: insights from knockout and knockdown studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Effects of RNA interference-mediated silencing of gamma-secretase complex components on cell sensitivity to caspase-3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

BACE1 Suppression by RNA Interference in Primary Cortical Neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Proline-directed phosphorylation and isomerization in mitotic regulation and in Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Effects of Cerebrolysin on neurogenesis in an APP transgenic model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

The roles of cyclin-dependent kinase 5 and glycogen synthase kinase 3 in tau hyperphosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Reduced prevalence of AD in users of NSAIDs and H2 receptor antagonists: the Cache County study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Nonsteroidal anti-inflammatory drug use and Alzheimer's disease: a case-control study in Rochester, Minnesota, 1980 through 1984.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Non-steroidal anti-inflammatory drugs have anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Aspirin and non-steroidal anti-inflammatory drugs inhibit amyloid-beta aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Inhibition of inducible nitric oxide synthase gene expression by indomethacin or ibuprofen in beta-amyloid protein-stimulated J774 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Scaffold of the cyclooxygenase-2 (COX-2) inhibitor carprofen provides Alzheimer gamma-secretase modulators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Acetylsalicylic acid decreases tau phosphorylation at serine 422

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Amelioration of the cerebrovascular amyloidosis in a transgenic model of Alzheimer's disease with the neurotrophic compound cerebrolysin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Efficacy of the peptidergic nootropic drug cerebrolysin in patients with senile dementia of the Alzheimer type (SDAT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

In vitro synaptotrophic effects of Cerebrolysin in NT2N cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Nerve growth factor and nootropic drug Cerebrolysin but not fibroblast growth factor can reduce spatial memory impairment elicited by fimbria-fornix transection: short-term study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Cerebrolysin ameliorates performance deficits, and neuronal damage in apolipoprotein E-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Neurogenesis in the adult human hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Alzheimer's disease drugs promote neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Stimulation of endogenous neurogenesis by anti-EFRH immunization in a transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

FGF-2-responsive neuronal progenitors reside in proliferative and quiescent regions of the adult rodent brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Resveratrol stimulates AMP kinase activity in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Prevention of Alzheimer's disease: Omega-3 fatty acid and phenolic anti-oxidant interventions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Does caffeine intake protect from Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Caffeine protects Alzheimer's mice against cognitive impairment and reduces brain beta-amyloid production

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Neuroprotection by caffeine and adenosine A2A receptor blockade of beta-amyloid neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Passive immunization against beta-amyloid peptide protects central nervous system (CNS) neurons from increased vulnerability associated with an Alzheimer's disease-causing mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Transcutaneous beta-amyloid immunization reduces cerebral beta-amyloid deposits without T cell infiltration and microhemorrhage

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Intravenous immunoglobulins containing antibodies against beta-amyloid for the treatment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Abeta species removal after abeta42 immunization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Vaccination of Alzheimer's model mice with Abeta derivative in alum adjuvant reduces Abeta burden without microhemorrhages

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Short amyloid-beta (Abeta) immunogens reduce cerebral Abeta load and learning deficits in an Alzheimer's disease mouse model in the absence of an Abeta-specific cellular immune response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Nonviral Abeta DNA vaccine therapy against Alzheimer's disease: long-term effects and safety

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Abeta42 gene vaccination reduces brain amyloid plaque burden in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Transgenic potato expressing Abeta reduce Abeta burden in Alzheimer's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Intravenous immunoglobulin enhances the clearance of fibrillar amyloid-beta peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Intracranial administration of deglycosylated C-terminal-specific anti-Abeta antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Deglycosylation of anti-beta amyloid antibodies inhibits microglia activation in BV-2 cellular model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Amelioration of amyloid load by anti-Abeta single-chain antibody in Alzheimer mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Anti-Abeta single-chain antibody delivery via adeno-associated virus for treatment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

Active immunization of mice with an Abeta-Hsp70 vaccine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.12.1853

10.1517/14712598.7.12.1853

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference