Proteomic analysis of Rac1 signaling regulation by guanine nucleotide exchange factors (Q37143218)

18 August 2017

Proteomic analysis of Rac1 signaling regulation by guanine nucleotide exchange factors (English)

1 reference

18 August 2017

Hadir Marei

1

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Angeliki Malliri

object named as

Angeliki Malliri

series ordinal

4

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Boris Macek

object named as

Boris Macek

series ordinal

3

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author name string

Alejandro Carpy

series ordinal

2

1 reference

18 August 2017

6 May 2016

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18 August 2017

14

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inferred from page(s)

published in

Cell Cycle

1 reference

18 August 2017

15

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18 August 2017

15

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18 August 2017

1961-1974

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Creative Commons Attribution 4.0 International

18 August 2017

start time

1 June 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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April 2022 Public Data File from Crossref

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4968972/fullTextXML

inferred from PubMed Central ID database lookup

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Menin interacts with IQGAP1 to enhance intercellular adhesion of beta-cells

6 September 2017

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6 September 2017

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A dual role for IQGAP1 in regulating exocytosis

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A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes

6 September 2017

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Probabilistic prediction and ranking of human protein-protein interactions

6 September 2017

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Tiam1-IRSp53 complex formation directs specificity of rac-mediated actin cytoskeleton regulation

6 September 2017

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IQGAP1: a key regulator of adhesion and migration

6 September 2017

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GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

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The RacGEF Tiam1 inhibits migration and invasion of metastatic melanoma via a novel adhesive mechanism.

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The role of the guanine nucleotide exchange factor Tiam1 in cellular migration, invasion, adhesion and tumor progression

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Regulation of p70 S6 kinase by complex formation between the Rac guanine nucleotide exchange factor (Rac-GEF) Tiam1 and the scaffold spinophilin

6 September 2017

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6 September 2017

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Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascade

6 September 2017

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Involvement of IQGAP1, an effector of Rac1 and Cdc42 GTPases, in cell-cell dissociation during cell scattering

6 September 2017

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IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling

6 September 2017

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Ankyrin-Tiam1 interaction promotes Rac1 signaling and metastatic breast tumor cell invasion and migration

6 September 2017

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Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b

6 September 2017

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CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration

6 September 2017

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Cdc42 and Rac1 regulate the interaction of IQGAP1 with beta-catenin

6 September 2017

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Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

6 September 2017

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Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion

6 September 2017

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PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

6 September 2017

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Guanine nucleotide exchange factors regulate specificity of downstream signaling from Rac and Cdc42.

6 September 2017

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Identification of a novel guanine nucleotide exchange factor for the Rho GTPase

6 September 2017

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IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4968972

A role for Rac in Tiam1-induced membrane ruffling and invasion

6 September 2017

1 reference

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Sequence of the human invasion-inducing TIAM1 gene, its conservation in evolution and its expression in tumor cell lines of different tissue origin.

6 September 2017

1 reference

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Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

6 September 2017

1 reference

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Human Protein Reference Database and Human Proteinpedia as discovery tools for systems biology.

6 September 2017

1 reference

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The guanine nucleotide exchange factor Tiam1 increases colon carcinoma growth at metastatic sites in an orthotopic nude mouse model.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4968972

Antisense Tiam1 down-regulates the invasiveness of 95D cells in vitro

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4968972

The Rac exchange factor Tiam1 is required for the establishment and maintenance of cadherin-based adhesions

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4968972

Expression of seven main Rho family members in gastric carcinoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4968972

Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4968972

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4968972

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4968972

Inhibition of invasion of epithelial cells by Tiam1-Rac signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4968972

HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4968972

Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4968972

Expression of Tiam-1 in the developing brain suggests a role for the Tiam-1-Rac signaling pathway in cell migration and neurite outgrowth.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4968972

Tandem affinity purification of protein complexes from mammalian cells by the Strep/FLAG (SF)-TAP tag.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4968972

Requirement for Rac1 in a K-ras induced lung cancer in the mouse.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4968972

IQGAP1 mediates VE-cadherin-based cell-cell contacts and VEGF signaling at adherence junctions linked to angiogenesis.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4968972

The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4968972

Functional and quantitative proteomics using SILAC

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1080%2F15384101.2016.1183852

Syndecan-2 regulates cell migration in colon cancer cells through Tiam1-mediated Rac activation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27152953

12 December 2020

inferred from PubMed ID database lookup

Overexpression of RhoA, Rac1, and Cdc42 GTPases is associated with progression in testicular cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27152953

12 December 2020

inferred from PubMed ID database lookup

Rho-like GTPases: their role in epithelial cell-cell adhesion and invasion

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27152953

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1080/15384101.2016.1183852

1 reference

18 August 2017

1 reference

PMC publication ID

4968972

18 August 2017

PubMed publication ID

27152953

1 reference

PMC publication ID

4968972