Inhibitory B7-family molecules in the tumour microenvironment (Q37171804)

18 August 2017

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title

Inhibitory B7-family molecules in the tumour microenvironment (English)

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18 August 2017

Weiping Zou

1

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PubMed ID

18500231

18 August 2017

Lieping Chen

series ordinal

2

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18 August 2017

1 June 2008

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Nature Reviews Immunology

18 August 2017

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18 August 2017

8

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18 August 2017

6

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18 August 2017

467-477

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Immunosuppressive networks in the tumour environment and their therapeutic relevance

18 August 2017

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Natural selection of tumor variants in the generation of "tumor escape" phenotypes

31 March 2020

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Immune system versus tumor: shifting the balance in favor of DCs and effective immunity

31 March 2020

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Does the immune system see tumors as foreign or self?

31 March 2020

1 reference

Dendritic cells: a journey from laboratory to clinic

31 March 2020

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The promise of cancer vaccines

31 March 2020

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IDO expression by dendritic cells: tolerance and tryptophan catabolism

31 March 2020

1 reference

Cancer vaccines: between the idea and the reality

31 March 2020

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Immunodominance and tumor escape

31 March 2020

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Dendritic cells as therapeutic vaccines against cancer

31 March 2020

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Mechanisms and functional significance of tumour-induced dendritic-cell defects

31 March 2020

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Regulation of immune responses by L-arginine metabolism

31 March 2020

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Regulatory T cells, tumour immunity and immunotherapy

31 March 2020

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Regulatory T-cell compartmentalization and trafficking

31 March 2020

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Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

31 March 2020

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Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

31 March 2020

1 reference

Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity

31 March 2020

1 reference

31 March 2020

The B7-CD28 superfamily

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Checkpoint blockade in cancer immunotherapy

31 March 2020

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B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion

31 March 2020

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Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

31 March 2020

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Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction

31 March 2020

1 reference

Blockade of B7-H1 improves myeloid dendritic cell–mediated antitumor immunity

31 March 2020

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Blockade of B7-H1 Suppresses the Development of Chronic Intestinal Inflammation

31 March 2020

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Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses

31 March 2020

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Costimulating aberrant T cell responses by B7-H1 autoantibodies in rheumatoid arthritis

31 March 2020

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B7-H1 is a ubiquitous antiapoptotic receptor on cancer cells

31 March 2020

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B7-H4, a molecule of the B7 family, negatively regulates T cell immunity

31 March 2020

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B7x: a widely expressed B7 family member that inhibits T cell activation

31 March 2020

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B7S1, a novel B7 family member that negatively regulates T cell activation

31 March 2020

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B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma

31 March 2020

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BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1

31 March 2020

1 reference

B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator

31 March 2020

1 reference

Attenuating lymphocyte activity: the crystal structure of the BTLA-HVEM complex

31 March 2020

1 reference

A coreceptor interaction between the CD28 and TNF receptor family members B and T lymphocyte attenuator and herpesvirus entry mediator

31 March 2020

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Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production

31 March 2020

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Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma

31 March 2020

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NK cells that are activated by CXCL10 can kill dormant tumor cells that resist CTL-mediated lysis and can express B7-H1 that stimulates T cells.

31 March 2020

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B7-H1 is expressed by human endothelial cells and suppresses T cell cytokine synthesis

31 March 2020

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Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway.

31 March 2020

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Mast cells enhance T cell activation: importance of mast cell costimulatory molecules and secreted TNF

31 March 2020

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B7 family molecules: novel immunomodulators at the maternal-fetal interface

31 March 2020

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B7-H1-induced apoptosis as a mechanism of immune privilege of corneal allografts

31 March 2020

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Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

31 March 2020

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Dendritic cells infiltrating human non-small cell lung cancer are blocked at immature stage

31 March 2020

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Characterization of human lung tumor-associated fibroblasts and their ability to modulate the activation of tumor-associated T cells

31 March 2020

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Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target

31 March 2020

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The B7-H1 (PD-L1) T lymphocyte-inhibitory molecule is expressed in breast cancer patients with infiltrating ductal carcinoma: correlation with important high-risk prognostic factors.

31 March 2020

1 reference

Genomic Organization and Expression Analysis of B7-H4, an Immune Inhibitory Molecule of the B7 Family

31 March 2020

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B7-h4 is highly expressed in ductal and lobular breast cancer

31 March 2020

1 reference

Differential gene expression profiles between tumor biopsies and short-term primary cultures of ovarian serous carcinomas: Identification of novel molecular biomarkers for early diagnosis and therapy

31 March 2020

1 reference

B7-H4 overexpression in ovarian tumors

31 March 2020

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B7-H4 Is a Novel Membrane-Bound Protein and a Candidate Serum and Tissue Biomarker for Ovarian Cancer

31 March 2020

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The immunomodulatory protein B7-H4 is overexpressed in breast and ovarian cancers and promotes epithelial cell transformation

31 March 2020

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Relationship between B7-H4, regulatory T cells, and patient outcome in human ovarian carcinoma

31 March 2020

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B7-H4 expression in renal cell carcinoma and tumor vasculature: associations with cancer progression and survival

31 March 2020

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Cancer and the chemokine network

31 March 2020

1 reference

31 March 2020

Inflammation and cancer

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PD-L1 partially protects renal tubular epithelial cells from the attack of CD8+ cytotoxic T cells

31 March 2020

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PD-L1 is induced in hepatocytes by viral infection and by interferon-α and -γ and mediates T cell apoptosis

31 March 2020

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Interferon-beta enhances monocyte and dendritic cell expression of B7-H1 (PD-L1), a strong inhibitor of autologous T-cell activation: relevance for the immune modulatory effect in multiple sclerosis

31 March 2020

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Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells

31 March 2020

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Reciprocal control of T helper cell and dendritic cell differentiation

31 March 2020

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Cellular responses to interferon-gamma

31 March 2020

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Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase

31 March 2020

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Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism.

31 March 2020

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Gr-1+ myeloid cells derived from tumor-bearing mice inhibit primary T cell activation induced through CD3/CD28 costimulation

31 March 2020

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Tumor-infiltrating macrophages induce apoptosis in activated CD8(+) T cells by a mechanism requiring cell contact and mediated by both the cell-associated form of TNF and nitric oxide.

31 March 2020

1 reference

Prospects for adoptive T cell therapy

31 March 2020

1 reference

Melanoma immunotherapy: new dreams or solid hopes?

31 March 2020

1 reference

New treatment options for patients with melanoma: review of melanoma-derived T-cell epitope-based peptide vaccines.

31 March 2020

1 reference

Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes

31 March 2020

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IFN-gamma mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy

31 March 2020

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Cutting edge: induction of B7-H4 on APCs through IL-10: novel suppressive mode for regulatory T cells

31 March 2020

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B7-H1 determines accumulation and deletion of intrahepatic CD8(+) T lymphocytes.

31 March 2020

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PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells

31 March 2020

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Generation and characterization of B7-H4/B7S1/B7x-deficient mice

31 March 2020

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PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells

31 March 2020

1 reference

Predominant expression of B7-H1 and its immunoregulatory roles in oral squamous cell carcinoma

31 March 2020

1 reference

The role of leukemia-derived B7-H1 (PD-L1) in tumor-T-cell interactions in humans

31 March 2020

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Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade

31 March 2020

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In a model of tumor dormancy, long-term persistent leukemic cells have increased B7-H1 and B7.1 expression and resist CTL-mediated lysis.

31 March 2020

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Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up.

31 March 2020

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B7-H1 expression on non-small cell lung cancer cells and its relationship with tumor-infiltrating lymphocytes and their PD-1 expression

31 March 2020

1 reference

Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer

31 March 2020

1 reference

Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer

31 March 2020

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Immunohistochemical localization of programmed death-1 ligand-1 (PD-L1) in gastric carcinoma and its clinical significance

31 March 2020

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B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome

31 March 2020

1 reference

Immune signatures of murine and human cancers reveal unique mechanisms of tumor escape and new targets for cancer immunotherapy.

31 March 2020

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Intrahepatic expression of the co-stimulatory molecules programmed death-1, and its ligands in autoimmune liver disease.

31 March 2020

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In vivo immune modulatory activity of hepatic stellate cells in mice.

31 March 2020

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B7-H1 (programmed death-1 ligand) on dendritic cells is involved in the induction and maintenance of T cell anergy.

31 March 2020

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Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4.

31 March 2020

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Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway.

31 March 2020

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Interaction between B7-H1 and PD-1 determines initiation and reversal of T-cell anergy

31 March 2020

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Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells

31 March 2020

1 reference

Programmed death-1 blockade enhances expansion and functional capacity of human melanoma antigen-specific CTLs.

31 March 2020

1 reference

Restoring function in exhausted CD8 T cells during chronic viral infection

31 March 2020

1 reference

PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection

31 March 2020

1 reference

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

31 March 2020

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Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

31 March 2020

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Infections as a major preventable cause of human cancer

31 March 2020

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PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells

31 March 2020

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Blockade of PD-L1 (B7-H1) augments human tumor-specific T cell responses in vitro

31 March 2020

1 reference

B7-H1 expression is upregulated in peripheral blood CD14+ monocytes of patients with chronic hepatitis B virus infection, which correlates with higher serum IL-10 levels

31 March 2020

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B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression

31 March 2020

1 reference

Cutting Edge: Murine Vascular Endothelium Activates and Induces the Generation of Allogeneic CD4+25+Foxp3+ Regulatory T Cells

31 March 2020

1 reference

Expression of the programmed death ligand 1, B7-H1, on gastric epithelial cells after Helicobacter pylori exposure promotes development of CD4+ CD25+ FoxP3+ regulatory T cells

31 March 2020

1 reference

Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

31 March 2020

1 reference

Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma

31 March 2020

1 reference

A Paracrine Loop between Tumor Cells and Macrophages Is Required for Tumor Cell Migration in Mammary Tumors

31 March 2020

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Tumour-educated macrophages promote tumour progression and metastasis

31 March 2020

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Inflammation and necrosis promote tumour growth

31 March 2020

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Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

31 March 2020

1 reference

Local expression of B7-H1 promotes organ-specific autoimmunity and transplant rejection

31 March 2020

1 reference

Differential role of programmed death-ligand 1 [corrected] and programmed death-ligand 2 [corrected] in regulating the susceptibility and chronic progression of experimental autoimmune encephalomyelitis

31 March 2020

1 reference

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

31 March 2020

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Tissue expression of PD-L1 mediates peripheral T cell tolerance.

31 March 2020

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Antibody-mediated signaling through PD-1 costimulates T cells and enhances CD28-dependent proliferation.

31 March 2020

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Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

31 March 2020

1 reference

Targeting molecular and cellular inhibitory mechanisms for improvement of antitumor memory responses reactivated by tumor cell vaccine

31 March 2020

1 reference

HSP70 vaccine in combination with gene therapy with plasmid DNA encoding sPD-1 overcomes immune resistance and suppresses the progression of pulmonary metastatic melanoma

31 March 2020

1 reference

Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-{gamma} and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway.

31 March 2020

1 reference

Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer.

31 March 2020

1 reference

Costimulatory molecule B7-H1 in primary and metastatic clear cell renal cell carcinoma

31 March 2020

1 reference

Overexpression of B7-H1 (PD-L1) significantly associates with tumor grade and postoperative prognosis in human urothelial cancers

31 March 2020

1 reference

PD-L1 (B7-H1) expression by urothelial carcinoma of the bladder and BCG-induced granulomata: associations with localized stage progression.

31 March 2020

1 reference

B7-H3 and B7-H4 expression in non-small-cell lung cancer

31 March 2020

1 reference

B7-H4 (DD-O110) is overexpressed in high risk uterine endometrioid adenocarcinomas and inversely correlated with tumor T-cell infiltration

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRI2326

1 reference

release_u7a3nssre5ds7pgke2j5j5okmm

18 August 2017

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Fatcat

https://api.fatcat.wiki/v0/release/u7a3nssre5ds7pgke2j5j5okmm

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

18500231

1 reference

PubMed ID

18500231