Regulation of smooth muscle contraction by small GTPases (Q37649264)

21 August 2017

1 reference

title

Regulation of smooth muscle contraction by small GTPases (English)

1 reference

Gene Ontology release 2020-05-02

21 August 2017

1 reference

Gene Ontology ID

GO:0090075

relaxation of vascular associated smooth muscle

1 reference

Gene Ontology release 2020-05-02

Sandra Puetz

1

1 reference

PubMed ID

19996365

21 August 2017

Lubomir T Lubomirov

series ordinal

2

1 reference

PubMed ID

19996365

21 August 2017

Gabriele Pfitzer

series ordinal

3

1 reference

21 August 2017

1 December 2009

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21 August 2017

1 reference

21 August 2017

24

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21 August 2017

342-356

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Bacterial cytotoxins: targeting eukaryotic switches

21 August 2017

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Stretch of the vascular wall induces smooth muscle differentiation by promoting actin polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Arachidonic acid-induced Ca2+ sensitization of smooth muscle contraction through activation of Rho-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Taking Rho GTPases to the next level: the cellular functions of atypical Rho GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

The selectivity of protein kinase inhibitors: a further update

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

PKC is required for activation of ROCK by RhoA in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Dose-to-duration encoding and signaling beyond saturation in intracellular signaling networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

GAP control: regulating the regulators of small GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Smooth muscle cell calcium activation mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Characterization of G alpha 13-dependent plasma membrane recruitment of p115RhoGEF

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Epac/Rap and PKA are novel mechanisms of ANP-induced Rac-mediated pulmonary endothelial barrier protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

RhoA/Rho-kinase suppresses endothelial nitric oxide synthase in the penis: a mechanism for diabetes-associated erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Oxidized LDL increases the sensitivity of the contractile apparatus in isolated resistance arteries for Ca(2+) via a rho- and rho kinase-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Sphingosine kinase modulates microvascular tone and myogenic responses through activation of RhoA/Rho kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Nitric oxide-induced decrease in calcium sensitivity of resistance arteries is attributable to activation of the myosin light chain phosphatase and antagonized by the RhoA/Rho kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho GTPase, Rac1, regulates Skp2 levels, vascular smooth muscle cell proliferation, and intima formation in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

GEFs and GAPs: critical elements in the control of small G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

The GTPase superfamily: a conserved switch for diverse cell functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Angiotensin II induces RhoA activation through SHP2-dependent dephosphorylation of the RhoGAP p190A in vascular smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Opposing roles of endothelial and smooth muscle phosphatidylinositol 3-kinase in vasoconstriction: effects of rho-kinase and hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho and Rac take center stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Modulation of RhoA-Rho kinase-mediated Ca2+ sensitization of rabbit myometrium during pregnancy - role of Rnd3

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

The Dbl family of oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Function and regulation of Rnd proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Interleukin-13 augments bronchial smooth muscle contractility with an up-regulation of RhoA protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Potent activation of RhoA by Galpha q and Gq-coupled receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Molecular mechanisms of detrusor and corporal myocyte contraction: identifying targets for pharmacotherapy of bladder and erectile dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Phosphorylation of the myosin phosphatase inhibitors, CPI-17 and PHI-1, by integrin-linked kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

GDIs: central regulatory molecules in Rho GTPase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Phosphorylation of RhoGDI by Src regulates Rho GTPase binding and cytosol-membrane cycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Inhibition of cGMP-dependent protein kinase reverses phenotypic modulation of vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Tyrosine kinase inhibitors suppress agonist-induced contraction in smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Ca2+-dependent rapid Ca2+ sensitization of contraction in arterial smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Involvement of Rho kinase and protein kinase C in carbachol-induced calcium sensitization in beta-escin skinned rat and guinea-pig bladders

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Activated Galphaq family members induce Rho GTPase activation and Rho-dependent actin filament assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Serine phosphorylation negatively regulates RhoA in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Structural elements, mechanism, and evolutionary convergence of Rho protein-guanine nucleotide exchange factor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho GTPases in cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Histamine-induced vasoconstriction involves phosphorylation of a specific inhibitor protein for myosin phosphatase by protein kinase C alpha and delta isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

A novel protein phosphatase-1 inhibitory protein potentiated by protein kinase C. Isolation from porcine aorta media and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho-associated kinase of chicken gizzard smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Identification of a novel human Rho protein with unusual properties: GTPase deficiency and in vivo farnesylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

The effects of the Rho-kinase inhibitor Y-27632 on arachidonic acid-, GTPgammaS-, and phorbol ester-induced Ca2+-sensitization of smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Inhibition of RhoA translocation and calcium sensitization by in vivo ADP-ribosylation with the chimeric toxin DC3B

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

RGS-containing RhoGEFs: the missing link between transforming G proteins and Rho?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Role for G(12)/G(13) in agonist-induced vascular smooth muscle cell contraction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Regulation by GDI of RhoA/Rho-kinase-induced Ca2+ sensitization of smooth muscle myosin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Role of guanine nucleotide-binding proteins--ras-family or trimeric proteins or both--in Ca2+ sensitization of smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Exchange factors, effectors, GAPs and motor proteins: common thermodynamic and kinetic principles for different functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Inhibition of RhoA/Rho kinase pathway is involved in the beneficial effect of sildenafil on pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Actin cytoskeletal dynamics in smooth muscle: a new paradigm for the regulation of smooth muscle contraction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Ca2+-independent phospholipase A2 is required for agonist-induced Ca2+ sensitization of contraction in vascular smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Phosphorylation of CPI-17, an inhibitor of myosin phosphatase, by protein kinase N.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Regulation of myosin light chain kinase expression by angiotensin II in hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Role of protein phosphatase type 1 in contractile functions: myosin phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Myosin light chain kinase is central to smooth muscle contraction and required for gastrointestinal motility in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Gq/G13 signaling by ET-1 in smooth muscle: MYPT1 phosphorylation via ETA and CPI-17 dephosphorylation via ETB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Increased PDZ-RhoGEF/RhoA/Rho kinase signaling in small mesenteric arteries of angiotensin II-induced hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Agonist-dependent modulation of Ca2+ sensitivity in rabbit pulmonary artery smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Current topics in the regulatory mechanism underlying the Ca2+ sensitization of the contractile apparatus in vascular smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Therapeutic potential of rho-kinase inhibitors in cardiovascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Signaling to the Rho GTPases: networking with the DH domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Protein Kinase Cα-Induced p115RhoGEF Phosphorylation Signals Endothelial Cytoskeletal Rearrangement

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Regulation of NADPH oxidases: the role of Rac proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Mechanisms of smooth muscle contraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Signaling pathways mediating gastrointestinal smooth muscle contraction and MLC20 phosphorylation by motilin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Unzipping the Role of Myosin Light Chain Phosphatase in Smooth Muscle Cell Relaxation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Treatment of pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

The regulation of smooth muscle contractility by zipper-interacting protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

A major role for the rho-associated coiled coil forming protein kinase in G-protein-mediated Ca2+ sensitization through inhibition of myosin phosphatase in rabbit trachea

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Real-time evaluation of myosin light chain kinase activation in smooth muscle tissues from a transgenic calmodulin-biosensor mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Essential role of rho kinase in the Ca2+ sensitization of prostaglandin F(2alpha)-induced contraction of rabbit aortae

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Myosin phosphatase: structure, regulation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho-glucosylating Clostridium difficile toxins A and B: new insights into structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Dependency of detrusor contractions on calcium sensitization and calcium entry through LOE-908-sensitive channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Regulation of endothelial nitric oxide synthase expression in the vascular wall and in mononuclear cells from hypercholesterolemic rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Ca2+ sensitization via phosphorylation of myosin phosphatase targeting subunit at threonine-855 by Rho kinase contributes to the arterial myogenic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Signaling networks: the origins of cellular multitasking

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

The function of myosin and myosin light chain kinase phosphorylation in smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Identification of calponin as a novel substrate of Rho-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Ca2+ localization and sensitivity in vascular smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Smooth muscle of telokin-deficient mice exhibits increased sensitivity to Ca2+ and decreased cGMP-induced relaxation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Smooth muscle signalling pathways in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Phosphorylation of the myosin phosphatase targeting subunit and CPI-17 during Ca2+ sensitization in rabbit smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

G protein-mediated inhibition of myosin light-chain phosphatase in vascular smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Tiam1 and Rac1 are required for platelet-activating factor-induced endothelial junctional disassembly and increase in vascular permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Interaction between src family kinases and rho-kinase in agonist-induced Ca2+-sensitization of rat pulmonary artery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Molecular mechanisms of beta-adrenergic relaxation of airway smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Phosphorylation of CPI-17, an inhibitory phosphoprotein of smooth muscle myosin phosphatase, by Rho-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Elevated concentrations of sphingosylphosphorylcholine in cerebrospinal fluid after subarachnoid hemorrhage: a possible role as a spasmogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Cyclic GMP causes Ca2+ desensitization in vascular smooth muscle by activating the myosin light chain phosphatase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Invited review: cGMP-dependent protein kinase signaling mechanisms in smooth muscle: from the regulation of tone to gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Regulation of Rho/ROCK signaling in airway smooth muscle by membrane potential and [Ca2+]i

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho kinases in cardiovascular physiology and pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Regulation of Rho proteins by phosphorylation in the cardiovascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho exchange factors in the cardiovascular system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Clostridium difficile toxin B inhibits carbachol-induced force and myosin light chain phosphorylation in guinea-pig smooth muscle: role of Rho proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Modulation of vascular smooth muscle signaling by reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho‐kinase inhibitor inhibits both myosin phosphorylation‐dependent and ‐independent enhancement of myofilament Ca2+ sensitivity in the bovine middle cerebral artery

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Regulation of vascular reactivity by established and emerging GPCRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Protein kinase C-alpha signals rho-guanine nucleotide dissociation inhibitor phosphorylation and rho activation and regulates the endothelial cell barrier function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Membrane depolarization-induced contraction of rat caudal arterial smooth muscle involves Rho-associated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho-dependent agonist-induced spatio-temporal change in myosin phosphorylation in smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Myosin light chain kinase activation and calcium sensitization in smooth muscle in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho GTPase-activating proteins in cell regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Stimulus-specific patterns of intracellular calcium levels in smooth muscle of ferret portal vein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Invited review: cross-bridge regulation by thin filament-associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho-kinase contributes to sustained RhoA activation through phosphorylation of p190A RhoGAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Signaling for contraction and relaxation in smooth muscle of the gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Sustained muscle contraction induced by agonists, growth factors, and Ca(2+) mediated by distinct PKC isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Differential signalling by muscarinic receptors in smooth muscle: m2-mediated inactivation of myosin light chain kinase via Gi3, Cdc42/Rac1 and p21-activated kinase 1 pathway, and m3-mediated MLC20 (20 kDa regulatory light chain of myosin II) phosph

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Blockade of maitotoxin-induced endothelial cell lysis by glycine and L-alanine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho kinase inhibitor HA-1077 prevents Rho-mediated myosin phosphatase inhibition in smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Hydroxyfasudil, an active metabolite of fasudil hydrochloride, relaxes the rabbit basilar artery by disinhibition of myosin light chain phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Involvement of Src family protein tyrosine kinases in Ca(2+) sensitization of coronary artery contraction mediated by a sphingosylphosphorylcholine-Rho-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

The small GTPase Rho: cellular functions and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Thromboxane A2-induced bi-directional regulation of cerebral arterial tone

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Agonist-induced changes in the phosphorylation of the myosin- binding subunit of myosin light chain phosphatase and CPI17, two regulatory factors of myosin light chain phosphatase, in smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Distinct pathways of Ca(2+) sensitization in porcine coronary artery: effects of Rho-related kinase and protein kinase C inhibition on force and intracellular Ca(2+).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Involvement ofrhoin GTPγS-induced enhancement of phosphorylation of 20 kDa myosin light chain in vascular smooth muscle cells: inhibition of phosphatase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Physiological role of ROCKs in the cardiovascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Serine phosphorylation differentially affects RhoA binding to effectors: implications to NGF-induced neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

EphA4-mediated Rho activation via Vsm-RhoGEF expressed specifically in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Signal-crosstalk between Rho/ROCK and c-Jun NH2-terminal kinase mediates migration of vascular smooth muscle cells stimulated by angiotensin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Role of Rho proteins in carbachol-induced contractions in intact and permeabilized guinea-pig intestinal smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Molecular regulation of vascular smooth muscle cell differentiation in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Direct association of RhoA with specific domains of PKC-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

RhoA-Rho kinase pathway mediates thrombin- and U-46619-induced phosphorylation of a myosin phosphatase inhibitor, CPI-17, in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Invited review: regulation of myosin phosphorylation in smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Thiophosphorylation-induced Ca(2+) sensitization of guinea-pig ileum contractility is not mediated by Rho-associated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Phosphorylation of GTP dissociation inhibitor by PKA negatively regulates RhoA

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

PKA inhibits RhoA activation: a protection mechanism against endothelial barrier dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

G protein mediated signaling pathways in lysophospholipid induced cell proliferation and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Regulation of smooth muscle calcium sensitivity: KCl as a calcium-sensitizing stimulus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

RhoA kinase and protein kinase C participate in regulation of rabbit stomach fundus smooth muscle contraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Distinct patterns of actin organization regulated by the small GTP-binding proteins Rac and Rho.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rocks: multifunctional kinases in cell behaviour

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Receptors coupled to heterotrimeric G proteins of the G12 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Phosphorylation of serine 188 protects RhoA from ubiquitin/proteasome-mediated degradation in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rac inhibits thrombin-induced Rho activation: evidence of a Pak-dependent GTPase crosstalk

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Physical and functional interactions of Galphaq with Rho and its exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

The role of Rho in G protein-coupled receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho activation in excitatory agonist-stimulated vascular smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Ca2+-dependent activation of Rho and Rho kinase in membrane depolarization-induced and receptor stimulation-induced vascular smooth muscle contraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Tyrosine phosphorylation as a convergent pathway of heterotrimeric G protein- and rho protein-mediated Ca2+ sensitization of smooth muscle of rabbit mesenteric artery

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Augmented agonist-induced Ca(2+)-sensitization of coronary artery contraction in genetically hypertensive rats. Evidence for altered signal transduction in the coronary smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Cyclic GMP-dependent protein kinase signaling pathway inhibits RhoA-induced Ca2+ sensitization of contraction in vascular smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Sildenafil prevents change in RhoA expression induced by chronic hypoxia in rat pulmonary artery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

RhoA expression is controlled by nitric oxide through cGMP-dependent protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

GTPase activating proteins: structural and functional insights 18 years after discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

RHO SIGNALING in vascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho kinase polymorphism influences blood pressure and systemic vascular resistance in human twins: role of heredity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho-kinase inhibition and electromechanical coupling in rat and guinea-pig ureter smooth muscle: Ca2+-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Differential association and localization of myosin phosphatase subunits during agonist-induced signal transduction in smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Sphingosylphosphorylcholine is a novel messenger for Rho-kinase-mediated Ca2+ sensitization in the bovine cerebral artery: unimportant role for protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

G(q)-dependent signalling by the lysophosphatidic acid receptor LPA(3) in gastric smooth muscle: reciprocal regulation of MYPT1 phosphorylation by Rho kinase and cAMP-independent PKA

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

ARAP3 is transiently tyrosine phosphorylated in cells attaching to fibronectin and inhibits cell spreading in a RhoGAP-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Modulation of Ca2+ sensitivity in smooth muscle by genistein and protein tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

A vascular cell-restricted RhoGAP, p73RhoGAP, is a key regulator of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Regulation of myosin phosphatase by a specific interaction with cGMP- dependent protein kinase Ialpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Inhibition of Rho-associated kinase blocks agonist-induced Ca2+ sensitization of myosin phosphorylation and force in guinea-pig ileum

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Small GTP-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

The small GTPase Cdc42 regulates actin polymerization and tension development during contractile stimulation of smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Comparative pharmacological analysis of Rho-kinase inhibitors and identification of molecular components of Ca2+ sensitization in the rat lower urinary tract.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Targeting and localized signalling by small GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Identification and characterization of the unique guanine nucleotide exchange factor, SmgGDS, in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

K+ depolarization induces RhoA kinase translocation to caveolae and Ca2+ sensitization of arterial muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Different molecular mechanisms for Rho family GTPase-dependent, Ca2+-independent contraction of smooth muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

C3 exoenzymes, novel insights into structure and action of Rho-ADP-ribosylating toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Receptor-dependent RhoA activation in G12/G13-deficient cells: genetic evidence for an involvement of Gq/G11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

L-type voltage-gated Ca2+ channels modulate expression of smooth muscle differentiation marker genes via a rho kinase/myocardin/SRF-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Excitation-transcription coupling in arterial smooth muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

ROCK isoform regulation of myosin phosphatase and contractility in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

The role of sphingosine-1-phosphate in smooth muscle contraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Mechanisms for reversible regulation between G13 and Rho exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

The Ras superfamily at a glance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho/Rho-kinase mediated signaling in physiology and pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Mammalian G proteins and their cell type specific functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Alpha1-adrenergic signaling mechanisms in contraction of resistance arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Thromboxane A2-induced contraction of rat caudal arterial smooth muscle involves activation of Ca2+ entry and Ca2+ sensitization: Rho-associated kinase-mediated phosphorylation of MYPT1 at Thr-855, but not Thr-697

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Inhibition of Contraction and Myosin Light Chain Phosphorylation in Guinea‐Pig Smooth Muscle by p21‐Activated Kinase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Expression of CPI-17 and myosin phosphatase correlates with Ca(2+) sensitivity of protein kinase C-induced contraction in rabbit smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Smooth muscle phosphatase is regulated in vivo by exclusion of phosphorylation of threonine 696 of MYPT1 by phosphorylation of Serine 695 in response to cyclic nucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Acceleration of myosin light chain dephosphorylation and relaxation of smooth muscle by telokin. Synergism with cyclic nucleotide-activated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Salicylates dilate blood vessels through inhibiting PYK2-mediated RhoA/Rho-kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Essential role for class II phosphoinositide 3-kinase alpha-isoform in Ca2+-induced, Rho- and Rho kinase-dependent regulation of myosin phosphatase and contraction in isolated vascular smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Activation of the Arp2/3 complex by N-WASp is required for actin polymerization and contraction in smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Distinctive G protein-dependent signaling in smooth muscle by sphingosine 1-phosphate receptors S1P1 and S1P2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Modulation of pulmonary vascular smooth muscle cell phenotype in hypoxia: role of cGMP-dependent protein kinase and myocardin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Actin reorganization in airway smooth muscle cells involves Gq and Gi-2 activation of Rho.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

Rho expression and activation in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

A Role for Rho in Smooth Muscle Phenotypic Regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

ARAP3 is a PI3K- and rap-regulated GAP for RhoA

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00023.2009

10.1152/PHYSIOL.00023.2009

21 January 2018

Identifiers

DOI

1 reference

21 August 2017

1 reference

PubMed ID

19996365