Regulation of Lrp6 phosphorylation (Q37709217)

22 August 2017

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title

Regulation of Lrp6 phosphorylation (English)

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22 August 2017

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Christof Niehrs

1

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PubMed ID

20229235

22 August 2017

Jinlong Shen

series ordinal

2

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22 August 2017

14 March 2010

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Cellular and Molecular Life Sciences

22 August 2017

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22 August 2017

67

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22 August 2017

15

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22 August 2017

2551-2562

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https://scigraph.springernature.com/pub.10.1007/s00018-010-0329-3

22 August 2017

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cites work

Glycogen synthase kinase-3--an overview of an over-achieving protein kinase

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00018-010-0329-3

Novel members of the cdc2-related kinase family in Drosophila: cdk4/6, cdk5, PFTAIRE, and PITSLRE kinase

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00018-010-0329-3

Identification of sites of phosphorylation by G-protein-coupled receptor kinase 2 in beta-tubulin

21 January 2018

1 reference

12 December 2020

R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling.

1 reference

12 December 2020

Local activation of protein kinase A inhibits morphogenetic movements during Xenopus gastrulation

1 reference

12 December 2020

The role of the casein kinase 1 (CK1) family in different signaling pathways linked to cancer development

1 reference

12 December 2020

Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in Drosophila.

1 reference

12 December 2020

beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation

1 reference

12 December 2020

PTH/cAMP/PKA signaling facilitates canonical Wnt signaling via inactivation of glycogen synthase kinase-3beta in osteoblastic Saos-2 cells

1 reference

12 December 2020

The renaissance of GSK3

1 reference

12 December 2020

Oncogenic Adenomatous polyposis coli mutants impair the mitotic checkpoint through direct interaction with Mad2.

1 reference

12 December 2020

Multiple Wnt signaling pathways converge to orient the mitotic spindle in early C. elegans embryos

1 reference

12 December 2020

Wnt signaling controls the phosphorylation status of beta-catenin.

1 reference

12 December 2020

Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors

1 reference

12 December 2020

Mesd encodes an LRP5/6 chaperone essential for specification of mouse embryonic polarity

1 reference

12 December 2020

Beta-catenin regulation during the cell cycle: implications in G2/M and apoptosis

1 reference

12 December 2020

Phosphorylation-independent inhibition of parathyroid hormone receptor signaling by G protein-coupled receptor kinases

1 reference

12 December 2020

Binding and phosphorylation of tubulin by G protein-coupled receptor kinases.

1 reference

12 December 2020

Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins

1 reference

12 December 2020

Wnt-dependent spindle polarization in the early C. elegans embryo

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12 December 2020

Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation

1 reference

12 December 2020

The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation

1 reference

12 December 2020

Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow

1 reference

12 December 2020

The low density lipoprotein receptor-related protein 6 interacts with glycogen synthase kinase 3 and attenuates activity

1 reference

12 December 2020

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

1 reference

12 December 2020

Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis

1 reference

12 December 2020

Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling

1 reference

12 December 2020

Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation

1 reference

12 December 2020

An LDL-receptor-related protein mediates Wnt signalling in mice

1 reference

12 December 2020

Dickkopf-1 regulates gastrulation movements by coordinated modulation of Wnt/beta catenin and Wnt/PCP activities, through interaction with the Dally-like homolog Knypek

1 reference

12 December 2020

Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signaling

1 reference

12 December 2020

Inactivation of rabbit muscle glycogen synthase by glycogen synthase kinase-3. Dominant role of the phosphorylation of Ser-640 (site-3a).

1 reference

12 December 2020

GTP-binding-protein-coupled receptor kinase 2 (GRK2) binds and phosphorylates tubulin.

1 reference

12 December 2020

Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins

1 reference

12 December 2020

LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin

1 reference

12 December 2020

Multiple levels of cyclin specificity in cell-cycle control

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12 December 2020

Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6.

1 reference

12 December 2020

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12 December 2020

The role of the Ser/Thr cluster in the phosphorylation of PPPSP motifs in Wnt coreceptors

1 reference

12 December 2020

Role of PKA as a negative regulator of PCP signaling pathway during Xenopus gastrulation movements.

1 reference

12 December 2020

Axin localizes to the centrosome and is involved in microtubule nucleation

1 reference

12 December 2020

The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization

1 reference

12 December 2020

Identification of a role for beta-catenin in the establishment of a bipolar mitotic spindle

1 reference

12 December 2020

Akt participation in the Wnt signaling pathway through Dishevelled

1 reference

12 December 2020

Cell cycle: cyclin guides the way

1 reference

12 December 2020

A mechanism for Wnt coreceptor activation

1 reference

12 December 2020

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

1 reference

12 December 2020

Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled

1 reference

12 December 2020

Armadillo levels are reduced during mitosis in Drosophila.

1 reference

12 December 2020

The Wnt signaling pathway in development and disease

1 reference

12 December 2020

Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family

1 reference

12 December 2020

G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway.

1 reference

12 December 2020

Multiple PPPS/TP motifs act in a combinatorial fashion to transduce Wnt signaling through LRP6.

1 reference

12 December 2020

Parathyroid hormone signaling through low-density lipoprotein-related protein 6

1 reference

12 December 2020

The when and wheres of CDC25 phosphatases

1 reference

12 December 2020

The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway

1 reference

12 December 2020

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

1 reference

12 December 2020

Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP.

1 reference

12 December 2020

The casein kinase 1 family: participation in multiple cellular processes in eukaryotes

1 reference

12 December 2020

Ordered multisite protein phosphorylation. Analysis of glycogen synthase kinase 3 action using model peptide substrates

1 reference

12 December 2020

Alternative wnt signaling is initiated by distinct receptors.

1 reference

12 December 2020

Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.

1 reference

12 December 2020

Wnt signal amplification via activity, cooperativity, and regulation of multiple intracellular PPPSP motifs in the Wnt co-receptor LRP6.

1 reference

12 December 2020

Exogenous expression of beta-catenin regulates contact inhibition, anchorage-independent growth, anoikis, and radiation-induced cell cycle arrest

1 reference

12 December 2020

A Drosophila protein-interaction map centered on cell-cycle regulators

1 reference

12 December 2020

Glycogen synthase kinase 3: more than a namesake

1 reference

12 December 2020

Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization.

1 reference

12 December 2020

Pathway specificity by the bifunctional receptor frizzled is determined by affinity for wingless

1 reference

12 December 2020

Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling

1 reference

12 December 2020

The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo

1 reference

12 December 2020

Mutations in the APC tumour suppressor gene cause chromosomal instability

1 reference

12 December 2020

Mouse models of altered protein kinase A signaling

1 reference

12 December 2020

Processive phosphorylation: mechanism and biological importance

1 reference

12 December 2020

Cell cycle control of wnt receptor activation

1 reference

12 December 2020

Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin.

1 reference

12 December 2020

Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer

1 reference

12 December 2020

A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin

1 reference

12 December 2020

The G protein-coupled receptor kinase (GRK) interactome: role of GRKs in GPCR regulation and signaling

1 reference

12 December 2020

The DIX domain targets dishevelled to actin stress fibres and vesicular membranes

1 reference

12 December 2020

SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor

1 reference

12 December 2020

CKI, there's more than one: casein kinase I family members in Wnt and Hedgehog signaling

1 reference

12 December 2020

Frat is dispensable for canonical Wnt signaling in mammals

1 reference

12 December 2020

Wnt pathway components orient a mitotic spindle in the early Caenorhabditis elegans embryo without requiring gene transcription in the responding cell

1 reference

12 December 2020

Wnt signalling and its impact on development and cancer

1 reference

12 December 2020

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

1 reference

12 December 2020

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12 December 2020

TCF/LEF factor earn their wings

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12 December 2020

beta-catenin is a target for the ubiquitin-proteasome pathway

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12 December 2020

The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates

1 reference

12 December 2020

Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity

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12 December 2020

Axin localizes to mitotic spindles and centrosomes in mitotic cells

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12 December 2020

Lrp6 is required for convergent extension during Xenopus gastrulation

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12 December 2020

Dynamic recruitment of axin by Dishevelled protein assemblies

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12 December 2020

Phosphate groups as substrate determinants for casein kinase I action

1 reference

12 December 2020

Regulation of Wnt/beta-catenin signaling by protein kinases

1 reference

12 December 2020

Response of small intestinal epithelial cells to acute disruption of cell division through CDC25 deletion

1 reference

12 December 2020

Cyclin Y, a novel membrane-associated cyclin, interacts with PFTK1

1 reference

12 December 2020

Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction

1 reference

12 December 2020

A novel consensus phosphorylation motif in sulfatide- and cholesterol-3-sulfate-binding protein substrates for CK1 in vitro

1 reference

12 December 2020

The G protein-coupled receptor kinase 2 is a microtubule-associated protein kinase that phosphorylates tubulin

1 reference

12 December 2020

Negative regulation of LRP6 function by casein kinase I epsilon phosphorylation.

1 reference

12 December 2020

arrow encodes an LDL-receptor-related protein essential for Wingless signalling

1 reference

12 December 2020

beta-Catenin is a Nek2 substrate involved in centrosome separation

1 reference

12 December 2020

Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6

1 reference

12 December 2020

Synucleins are a novel class of substrates for G protein-coupled receptor kinases

1 reference

12 December 2020

Wnt and calcium signaling: beta-catenin-independent pathways

1 reference

12 December 2020

Inhibition of WNT signaling by G protein-coupled receptor (GPCR) kinase 2 (GRK2).

1 reference

12 December 2020

Adenomatous polyposis coli and EB1 localize in close proximity of the mother centriole and EB1 is a functional component of centrosomes.

1 reference

12 December 2020

Plasma membrane recruitment of dephosphorylated beta-catenin upon activation of the Wnt pathway.

1 reference

12 December 2020

APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment

1 reference

12 December 2020

Wnt/beta-catenin signaling in development and disease

1 reference

12 December 2020

Identification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG box

1 reference

12 December 2020

Principles of CDK regulation

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12 December 2020

The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression

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12 December 2020

The L63 gene is necessary for the ecdysone-induced 63E late puff and encodes CDK proteins required for Drosophila development

1 reference

12 December 2020

Frizzled and Dfrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development.

1 reference

12 December 2020

A new member of the frizzled family from Drosophila functions as a Wingless receptor

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12 December 2020

Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome.

1 reference

12 December 2020

Recognition and regulation of primary-sequence motifs by signaling modular domains

1 reference

12 December 2020

Casein kinase I gamma subfamily. Molecular cloning, expression, and characterization of three mammalian isoforms and complementation of defects in the Saccharomyces cerevisiae YCK genes

1 reference

12 December 2020

Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling

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12 December 2020

Regulation of wingless signaling by the CKI family in Drosophila limb development.

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12 December 2020

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12 December 2020

10.1007/S00018-010-0329-3

Identifiers

DOI

1 reference

22 August 2017

1 reference

PubMed ID

20229235