Smart siRNA Delivery Systems Based on Polymeric Nanoassemblies and Nanoparticles (Q37793079)

23 August 2017

title

Smart siRNA delivery systems based on polymeric nanoassemblies and nanoparticles (English)

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23 August 2017

Smart siRNA Delivery Systems Based on Polymeric Nanoassemblies and Nanoparticles (English)

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21 July 2024

main subject

nanoparticle

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small interfering RNA

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20874023

21 July 2024

2

Yukio Nagasaki

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23 August 2017

Atsushi Tamura

1

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23 August 2017

language of work or name

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1 September 2010

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full work available at URL

23 August 2017

http://www.futuremedicine.com/doi/abs/10.2217/nnm.10.76

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20874023

https://www.tandfonline.com/doi/pdf/10.2217/nnm.10.76

21 July 2024

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21 July 2024

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23 August 2017

volume

5

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23 August 2017

issue

7

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23 August 2017

page(s)

1089-1102

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Structural gene identification and mapping by DNA-mRNA hybrid-arrested cell-free translation

23 August 2017

cites work

1 reference

Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide

21 January 2018

1 reference

Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide

21 January 2018

1 reference

Natural and engineered nucleic acids as tools to explore biology

21 January 2018

1 reference

Antigene, ribozyme and aptamer nucleic acid drugs: progress and prospects

21 January 2018

1 reference

Nucleic-acid therapeutics: basic principles and recent applications

21 January 2018

1 reference

Antisense therapy for cancer

21 January 2018

1 reference

21 January 2018

1 reference

Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease

21 January 2018

1 reference

siRNAs: applications in functional genomics and potential as therapeutics

21 January 2018

1 reference

Utilizing RNA interference to enhance cancer drug discovery

21 January 2018

1 reference

RNAi therapeutics: a potential new class of pharmaceutical drugs

21 January 2018

1 reference

Progress towards in vivo use of siRNAs

21 January 2018

1 reference

Strategies for silencing human disease using RNA interference

21 January 2018

1 reference

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

1 reference

RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

21 January 2018

1 reference

RNA interference is mediated by 21- and 22-nucleotide RNAs

21 January 2018

1 reference

How cells respond to interferons

21 January 2018

1 reference

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

21 January 2018

1 reference

Knocking down barriers: advances in siRNA delivery

21 January 2018

1 reference

RNA interference and chemically modified small interfering RNAs

21 January 2018

1 reference

RNA Interference with chemically modified siRNA.

21 January 2018

1 reference

siRNA conjugate delivery systems

21 January 2018

1 reference

The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice.

21 January 2018

1 reference

Biodistribution of phosphodiester and phosphorothioate siRNA.

21 January 2018

1 reference

Efficient siRNA delivery with non-viral polymeric vehicles

21 January 2018

1 reference

Cationic lipids and polymers mediated vectors for delivery of siRNA.

21 January 2018

1 reference

Design and development of polymers for gene delivery

21 January 2018

1 reference

DNA condensation by multivalent cations

21 January 2018

1 reference

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

21 January 2018

1 reference

Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes

21 January 2018

1 reference

RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo

21 January 2018

1 reference

Poly(amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications

21 January 2018

1 reference

Dendrimers in gene delivery

21 January 2018

1 reference

PAMAM dendrimers for efficient siRNA delivery and potent gene silencing

21 January 2018

1 reference

In vivo siRNA delivery with dendritic poly(L-lysine) for the treatment of hypercholesterolemia

21 January 2018

1 reference

Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery

21 January 2018

1 reference

Chitosan-based formulations for delivery of DNA and siRNA.

21 January 2018

1 reference

The influence of polymeric properties on chitosan/siRNA nanoparticle formulation and gene silencing.

21 January 2018

1 reference

Development and characterisation of chitosan nanoparticles for siRNA delivery

21 January 2018

1 reference

RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system.

21 January 2018

1 reference

Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties

21 January 2018

1 reference

Effect of pegylation on pharmaceuticals

21 January 2018

1 reference

Poly(ethylene glycol)-modified nanocarriers for tumor-targeted and intracellular delivery

21 January 2018

1 reference

Effective drug delivery by PEGylated drug conjugates

21 January 2018

1 reference

PEGylation, successful approach to drug delivery

21 January 2018

1 reference

Chemistry for peptide and protein PEGylation

21 January 2018

1 reference

PEGylated nanoparticles for biological and pharmaceutical applications

21 January 2018

1 reference

Block copolymer micelles for drug delivery: design, characterization and biological significance

21 January 2018

1 reference

Block copolymer micelles for delivery of gene and related compounds

21 January 2018

1 reference

Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review

21 January 2018

1 reference

Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/SiRNA polyplexes

21 January 2018

1 reference

In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(-PEG)/siRNA complexes

21 January 2018

1 reference

Multifunctional nanocarriers

21 January 2018

1 reference

Ligand-targeted liposomes

21 January 2018

1 reference

Nanoparticle therapeutics: an emerging treatment modality for cancer

21 January 2018

1 reference

Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

21 January 2018

1 reference

Comparative evaluation of target-specific GFP gene silencing efficiencies for antisense ODN, synthetic siRNA, and siRNA plasmid complexed with PEI-PEG-FOL conjugate

21 January 2018

1 reference

Partial acetylation of polyethylenimine enhances in vitro gene delivery.

21 January 2018

1 reference

Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells

21 January 2018

1 reference

Simple modifications of branched PEI lead to highly efficient siRNA carriers with low toxicity.

21 January 2018

1 reference

Water-soluble lipopolymer for gene delivery

21 January 2018

1 reference

Water-soluble lipopolymer as an efficient carrier for gene delivery to myocardium

21 January 2018

1 reference

Efficient siRNA delivery using water soluble lipopolymer for anti-angiogenic gene therapy

21 January 2018

1 reference

Hydrophobically modified oligoethylenimines as highly efficient transfection agents for siRNA delivery

21 January 2018

1 reference

A highly efficient siRNA carrier of PBLG modified hyperbranched PEI.

21 January 2018

1 reference

Synthesis and in vitro characterization of an ABC triblock copolymer for siRNA delivery.

21 January 2018

1 reference

Monomolecular assembly of siRNA and poly(ethylene glycol)-peptide copolymers.

21 January 2018

1 reference

Biodegradable amphiphilic poly(ethylene oxide)-block-polyesters with grafted polyamines as supramolecular nanocarriers for efficient siRNA delivery

21 January 2018

1 reference

Supramolecular nanocarrier of siRNA from PEG-based block catiomer carrying diamine side chain with distinctive pKa directed to enhance intracellular gene silencing.

21 January 2018

1 reference

Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging

21 January 2018

1 reference

The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic.

21 January 2018

1 reference

Physicochemical and biological characterization of targeted, nucleic acid-containing nanoparticles

21 January 2018

1 reference

Impact of tumor-specific targeting and dosing schedule on tumor growth inhibition after intravenous administration of siRNA-containing nanoparticles

21 January 2018

1 reference

Breaking up the correlation between efficacy and toxicity for nonviral gene delivery

21 January 2018

1 reference

Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: disulfide bonds boost intracellular release of the cargo.

21 January 2018

1 reference

21 January 2018

1 reference

VEGF siRNA delivery system using arginine-grafted bioreducible poly(disulfide amine).

21 January 2018

1 reference

Synthesis and characterization of chemically condensed oligoethylenimine containing beta-aminopropionamide linkages for siRNA delivery.

21 January 2018

1 reference

Induction of apoptosis in murine neuroblastoma by systemic delivery of transferrin-shielded siRNA polyplexes for downregulation of Ran.

21 January 2018

1 reference

Poly(beta-amino ester) as a carrier for si/shRNA delivery in lung cancer cells

21 January 2018

1 reference

Acid-responsive linear polyethylenimine for efficient, specific, and biocompatible siRNA delivery

21 January 2018

1 reference

Environment-responsive block copolymer micelles with a disulfide cross-linked core for enhanced siRNA delivery

21 January 2018

1 reference

Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells.

21 January 2018

1 reference

pH-responsive oligodeoxynucleotide (ODN)-poly(ethylene glycol) conjugate through acid-labile beta-thiopropionate linkage: preparation and polyion complex micelle formation

21 January 2018

1 reference

Receptor-mediated delivery of foreign genes to hepatocytes

21 January 2018

1 reference

Smart polyion complex micelles for targeted intracellular delivery of PEGylated antisense oligonucleotides containing acid-labile linkages.

21 January 2018

1 reference

PEG conjugated VEGF siRNA for anti-angiogenic gene therapy

21 January 2018

1 reference

Intracellular siRNA delivery system using polyelectrolyte complex micelles prepared from VEGF siRNA-PEG conjugate and cationic fusogenic peptide

21 January 2018

1 reference

Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancer

21 January 2018

1 reference

Breathing life into polycations: functionalization with pH-responsive endosomolytic peptides and polyethylene glycol enables siRNA delivery

21 January 2018

1 reference

Synthesis and biological evaluation of a bioresponsive and endosomolytic siRNA-polymer conjugate.

21 January 2018

1 reference

Target-specific intracellular delivery of siRNA using degradable hyaluronic acid nanogels

21 January 2018

1 reference

Rational design of targeted cancer therapeutics through the multiconjugation of folate and cleavable siRNA to RAFT-synthesized (HPMA-s-APMA) copolymers

21 January 2018

1 reference

Reversible siRNA-polymer conjugates by RAFT polymerization

21 January 2018

1 reference

Impact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging

21 January 2018

1 reference

Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under in vivo conditions: effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emissi

21 January 2018

1 reference

Stimuli-responsive smart nanogels for cancer diagnostics and therapy

21 January 2018

1 reference

Enhanced cytoplasmic delivery of siRNA using a stabilized polyion complex based on PEGylated nanogels with a cross-linked polyamine structure.

21 January 2018

1 reference

Cytosolic delivery mediated via electrostatic surface binding of protein, virus, or siRNA cargos to pH-responsive core-shell gel particles

21 January 2018

1 reference

Peptide-functionalized nanogels for targeted siRNA delivery.

21 January 2018

1 reference

Corona-Stabilized Interpolyelectrolyte Complexes of SiRNA with Nonimmunogenic, Hydrophilic/Cationic Block Copolymers Prepared by Aqueous RAFT Polymerization†

21 January 2018

1 reference

Polymer brush-stabilized polyplex for a siRNA carrier with long circulatory half-life

21 January 2018

1 reference

The Proton Sponge: a Trick to Enter Cells the Viruses Did Not Exploit

21 January 2018

33

1 reference

Cholesteryl oligoarginine delivering vascular endothelial growth factor siRNA effectively inhibits tumor growth in colon adenocarcinoma

21 July 2024

77

1 reference

Enhanced growth inhibition of hepatic multicellular tumor spheroids by lactosylated poly(ethylene glycol)-siRNA conjugate formulated in PEGylated polyplexes.

21 July 2024

93

1 reference

Biodegradable Dextran Nanogels for RNA Interference: Focusing on Endosomal Escape and Intracellular siRNA Delivery

21 July 2024

111

1 reference

21 July 2024

Identifiers

DOI

10.2217/NNM.10.76

1 reference

23 August 2017

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