Inhibitors of succinate: quinone reductase/Complex II regulate production of mitochondrial reactive oxygen species and protect normal cells from ischemic damage but induce specific cancer cell death. (Q37921677)

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scientific article published on 24 August 2011

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English	Inhibitors of succinate: quinone reductase/Complex II regulate production of mitochondrial reactive oxygen species and protect normal cells from ischemic damage but induce specific cancer cell death.	scientific article published on 24 August 2011

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scholarly article

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11 February 2020

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Inhibitors of succinate: quinone reductase/Complex II regulate production of mitochondrial reactive oxygen species and protect normal cells from ischemic damage but induce specific cancer cell death (English)

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11 February 2020

reactive oxygen species

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Stephen J. Ralph

1

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11 February 2020

Rafael Moreno-Sanchez

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Sara Rodríguez-Enríquez

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Rafael Moreno-Sanchez

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object named as

Rafael Moreno-Sánchez

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25 August 2017

3

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Jiri Neuzil

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25 August 2017

author name string

Stephen J Ralph

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Sara Rodríguez-Enríquez

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25 August 2017

publication date

24 August 2011

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Pharmaceutical Research

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2695-2730

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11 February 2020

Crystal structure of mitochondrial respiratory membrane protein complex II

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The quinone-binding and catalytic site of complex II.

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Mitochondrial respiratory chain super-complex I-III in physiology and pathology

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Structure and organization of mitochondrial respiratory complexes: a new understanding of an old subject

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Mobility and function of coenzyme Q (ubiquinone) in the mitochondrial respiratory chain

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The mitochondrial respiratory chain

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Saturation kinetics of coenzyme Q in NADH and succinate oxidation in beef heart mitochondria

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The production of reactive oxygen species by complex I.

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Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation

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Mutual inhibition between NADH oxidase and succinoxidase activities in respiring submitochondrial particles.

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Superoxide is produced by the reduced flavin in mitochondrial complex I: a single, unified mechanism that applies during both forward and reverse electron transfer

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Long chain fatty acyl-CoA modulation of H(2)O (2) release at mitochondrial complex I.

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Succinate modulation of H2O2 release at NADH:ubiquinone oxidoreductase (Complex I) in brain mitochondria

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DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria

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Effect of glutathione depletion on sites and topology of superoxide and hydrogen peroxide production in mitochondria.

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Dependence of H2O2 formation by rat heart mitochondria on substrate availability and donor age.

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High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria

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Superoxide production by NADH:ubiquinone oxidoreductase (complex I) depends on the pH gradient across the mitochondrial inner membrane

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Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I).

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Generation of reactive oxygen species by the mitochondrial electron transport chain

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Succinate is the controller of O2-/H2O2 release at mitochondrial complex I : negative modulation by malate, positive by cyanide

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What are the sources of hydrogen peroxide production by heart mitochondria?

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The NADH-fumarate reductase system, a novel mitochondrial energy metabolism, is a new target for anticancer therapy in tumor microenvironments

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https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Mutation of succinate dehydrogenase subunit C results in increased O2.-, oxidative stress, and genomic instability

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Zinc is a potent inhibitor of thiol oxidoreductase activity and stimulates reactive oxygen species production by lipoamide dehydrogenase.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Crystal structure of aminomethyltransferase in complex with dihydrolipoyl-H-protein of the glycine cleavage system: Implications for recognition of lipoyl protein substrate, disease-related mutations, and reaction mechanism

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Mitochondrial longevity pathways.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Dihydrolipoyl dehydrogenase as a source of reactive oxygen species inhibited by caloric restriction and involved in Saccharomyces cerevisiae aging.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Mammalian sirtuins: biological insights and disease relevance

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Generation of reactive oxygen species in the reaction catalyzed by alpha-ketoglutarate dehydrogenase.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Tricarboxylic acid cycle flux and enzyme activities in the isolated working rat heart

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Influence of NAD-linked dehydrogenase activity on flux through oxidative phosphorylation

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

2-Oxo acid dehydrogenase complexes in redox regulation

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Mitochondrial complex II participates in normoxic and hypoxic regulation of α-keto acids in the murine heart.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Ubiquinone is reduced by lipoamide dehydrogenase and this reaction is potently stimulated by zinc

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Reduction of ubiquinone by lipoamide dehydrogenase

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Differential inhibitory effect of long-chain acyl-CoA esters on succinate and glutamate transport into rat liver mitochondria and its possible implications for long-chain fatty acid oxidation defects.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

The mechanism of palmitoyl-CoA inhibition of Ca2+ uptake in liver and heart mitochondria

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Pyruvate dehydrogenase, substrate specificity and product inhibition.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Regulation of heart muscle pyruvate dehydrogenase kinase

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A a

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Relative importance of pyruvate dehydrogenase interconversion and feed-back inhibition in the effect of fatty acids on pyruvate oxidation by rat heart mitochondria

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Regulation of glucose uptake by muscles. 10. Effects of alloxan-diabetes, starvation, hypophysectomy and adrenalectomy, and of fatty acids, ketone bodies and pyruvate, on the glycerol output and concentrations of free fatty acids, long-chain fatty a

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Control of the tricarboxylate cycle and its interactions with glycolysis during acetate utilization in rat heart

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Fasting induced alterations in mitochondrial palmitoyl-CoA metabolism may inhibit adipocyte pyruvate dehydrogenase activity

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Neurotoxicity of ammonia and fatty acids: differential inhibition of mitochondrial dehydrogenases by ammonia and fatty acyl coenzyme A derivatives

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Impact of short- and medium-chain organic acids, acylcarnitines, and acyl-CoAs on mitochondrial energy metabolism

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Metabolism of ketonic acids in animal tissues

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Antioxidant and prooxidant properties of mitochondrial Coenzyme Q.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Reactive oxygen and targeted antioxidant administration in endothelial cell mitochondria.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Mitochondrial targeted coenzyme Q, superoxide, and fuel selectivity in endothelial cells

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Interaction of the mitochondria-targeted antioxidant MitoQ with phospholipid bilayers and ubiquinone oxidoreductases

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Pro-oxidant mitochondrial matrix-targeted ubiquinone MitoQ10 acts as anti-oxidant at retarded electron transport or proton pumping within Complex I.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Inhibition of mammalian succinate dehydrogenase by carboxins

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Mitochondria as cancer drug targets.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Mitochondria as targets for cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Mitochondriotoxic compounds for cancer therapy

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Molecular mechanism of 'mitocan'-induced apoptosis in cancer cells epitomizes the multiple roles of reactive oxygen species and Bcl-2 family proteins.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Mitochondria as targets for cancer therapy

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Mitocans: mitochondrial targeted anti-cancer drugs as improved therapies and related patent documents

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Vitamin E analogues as a novel group of mitocans: anti-cancer agents that act by targeting mitochondria

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Mitocans as anti-cancer agents targeting mitochondria: lessons from studies with vitamin E analogues, inhibitors of complex II.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Vitamin E analogs, a novel group of "mitocans," as anticancer agents: the importance of being redox-silent

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Selective cancer cell killing by alpha-tocopheryl succinate

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

An integrated genomic analysis of human glioblastoma multiforme

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Metabolic control analysis indicates a change of strategy in the treatment of cancer

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

alpha-Tocopheryl succinate induces apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 function

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Alpha-tocopheryl succinate inhibits malignant mesothelioma by disrupting the fibroblast growth factor autocrine loop: mechanism and the role of oxidative stress.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Mitochondria play a central role in apoptosis induced by alpha-tocopheryl succinate, an agent with antineoplastic activity: comparison with receptor-mediated pro-apoptotic signaling

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Vitamin E analogs trigger apoptosis in HER2/erbB2-overexpressing breast cancer cells by signaling via the mitochondrial pathway.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Alpha-tocopheryl succinate selectively induces apoptosis in neuroblastoma cells: potential therapy of malignancies of the nervous system?

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Role of reactive oxygen species in the induction of apoptosis by alpha-tocopheryl succinate

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

High cytotoxicity of alpha-tocopheryl hemisuccinate to cancer cells is due to failure of their antioxidative defense systems

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Effects of oxygen on the antioxidant responses of normal and transformed cells

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Hepatic processing determines dual activity of alpha-tocopheryl succinate: a novel paradigm for a shift in biological activity due to pro-vitamin-to-vitamin conversion

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Vitamin E analogues as anticancer agents: lessons from studies with alpha-tocopheryl succinate

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

A peptide conjugate of vitamin E succinate targets breast cancer cells with high ErbB2 expression

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

A vitamin E analogue suppresses malignant mesothelioma in a preclinical model: a future drug against a fatal neoplastic disease?

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Alpha-tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

A Chinese hamster mutant cell line with a defect in the integral membrane protein CII-3 of complex II of the mitochondrial electron transport chain

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

The tumor suppressor cybL, a component of the respiratory chain, mediates apoptosis induction

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

The quinone binding site in Escherichia coli succinate dehydrogenase is required for electron transfer to the heme b.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

The iron-sulfur clusters in Escherichia coli succinate dehydrogenase direct electron flow

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

The contribution of mitochondrial respiratory complexes to the production of reactive oxygen species.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Bioenergetics and the formation of mitochondrial reactive oxygen species.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Hippo/Mst1 stimulates transcription of the proapoptotic mediator NOXA in a FoxO1-dependent manner

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

alpha-Tocopheryl succinate causes mitochondrial permeabilization by preferential formation of Bak channels

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex II

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Cyclosporin A prevents the hypoxic adaptation by activating hypoxia-inducible factor-1alpha Pro-564 hydroxylation

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Suppression of human tumor cell proliferation through mitochondrial targeting

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Diazoxide-mediated growth inhibition in human lung cancer cells via downregulation of beta-catenin-mediated cyclin D1 transcription

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Diazoxide protects mitochondria from anoxic injury: implications for myopreservation

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Potassium channel openers protect cardiac mitochondria by attenuating oxidant stress at reoxygenation

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Differential actions of cardioprotective agents on the mitochondrial death pathway

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Diazoxide triggers cardioprotection against apoptosis induced by oxidative stress

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Characterization of succinate dehydrogenase and α-glycerophosphate dehydrogenase in pancreatic islets

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Targeting nucleotide-requiring enzymes: implications for diazoxide-induced cardioprotection

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Towards the molecular mechanism of respiratory complex I.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

A model of the proton translocation mechanism of complex I

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

An analysis of some thermodynamic properties of iron-sulphur centres in site I of mitochondria

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Quinol:fumarate oxidoreductases and succinate:quinone oxidoreductases: phylogenetic relationships, metal centres and membrane attachment

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Role of the Rieske iron-sulfur protein midpoint potential in the protonmotive Q-cycle mechanism of the cytochrome bc1 complex

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Determining and understanding the control of flux. An illustration in submitochondrial particles of how to validate schemes of metabolic control

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Oedema formation with the vasodilators nifedipine and diazoxide

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Superoxide dismutase as a target for the selective killing of cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Supramolecular organization of tricarboxylic acid cycle enzymes

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0566-7

21 January 2018

Anaerobic and aerobic pathways for salvage of proximal tubules from hypoxia-induced mitochondrial injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Redox regulation of the mitochondrial K(ATP) channel in cardioprotection

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zinc ions inhibit the QP center of bovine heart mitochondrial bc1 complex by blocking a protonatable group

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A 1H NMR study of succinate synthesis from exogenous precursors in oxygen-deprived rat heart mitochondria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial ATP-sensitive K+ channels are redox-sensitive pathways that control reactive oxygen species production

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Introduction--preparation and properties of the enzymes and enzymes complexes of the mitochondrial oxidative phosphorylation system

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial complex II has a key role in mitochondrial-derived reactive oxygen species influence on plant stress gene regulation and defense

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ammonium-dependent hydrogen peroxide production by mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The unique physiology of solid tumors: opportunities (and problems) for cancer therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of mitochondrial metabolism by the diabetogenic thiadiazine diazoxide. I. Action on succinate dehydrogenase and TCA-cycle oxidations

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fumarate reductase activity of bovine heart succinate-ubiquinone reductase. New assay system and overall properties of the reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organization of Krebs tricarboxylic acid cycle enzymes in mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibition of succinate dehydrogenase by oxalacetate

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pathways of glutamate and glutamine oxidation by tumor cell mitochondria. Role of mitochondrial NAD(P)+-dependent malic enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of oxidative phosphorylation by palmitoyl-CoA in digitonin permeabilized fibroblasts: implications for long-chain fatty acid β-oxidation disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diminished inhibition of mitochondrial electron transfer from succinate to cytochrome c by thenoyltrifluoroacetone induced by antimycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of citrate synthase and malate dehydrogenase to mitochondrial inner membranes: tissue distribution and metabolite effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the succinate dehydrogenating system. Interaction of the mitochondrial succinate-ubiquinone reductase with pyridoxal phosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+-induced activation of succinate dehydrogenase and the regulation of mitochondrial oxidative reactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of ubiquinone by lipoamide dehydrogenase. An antioxidant regenerating pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Effect of research conditions on succinate oxidation in brain mitochondria in circulatory hypoxia]

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oedema formation with the vasodilators nifedipine and diazoxide: direct local effect or sodium retention?

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of de novo alanine synthesis in hypoxic heart muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of fibrosarcoma metastasis by elevated expression of manganese superoxide dismutase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alanine and succinate accumulation in the perfused rat heart during hypoxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reconstitution of respiratory control of succinate oxidation in submitochondrial particles

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of functional assembly in mitochondrial supercomplexes: a new insight into impaired mitochondrial function?

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reconstitution and partial purification of the glibenclamide-sensitive, ATP-dependent K+ channel from rat liver and beef heart mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Movement of the iron-sulfur head domain of cytochrome bc(1) transiently opens the catalytic Q(o) site for reaction with oxygen

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diazoxide, an inhibitor of succinate oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steady-state kinetics of the overall oxidative phosphorylation reaction in heart mitochondria. Determination of the coupling relationships between the respiratory reactions and miscellaneous observations concerning rate-limiting steps

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Valproic acid metabolites inhibit dihydrolipoyl dehydrogenase activity leading to impaired 2-oxoglutarate-driven oxidative phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ratio of oxidative phosphorylation complexes I-V in bovine heart mitochondria and the composition of respiratory chain supercomplexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-keto acid dehydrogenase complexes. XX. A kinetic study of the pyruvate dehydrogenase complex from bovine kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Further characterization of the Krebs tricarboxylic acid cycle metabolon

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Augmented conversion of aspartate and glutamate to succinate during anoxia in rabbit heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel therapy for liver cancer: direct intraarterial injection of a potent inhibitor of ATP production.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tricarboxylic acid cycle metabolites during ischemia in isolated perfused rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of calcium ions in regulation of mammalian intramitochondrial metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of the intramitochondrial P/O ratio

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maximum rate of oxygen consumption and quantitative histochemistry of succinate dehydrogenase in single muscle fibres of Xenopus laevis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Krebs cycle enzymes by hydrogen peroxide: A key role of [alpha]-ketoglutarate dehydrogenase in limiting NADH production under oxidative stress.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The control of flux

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitocans, a class of emerging anti-cancer drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Asymmetric and redox-specific binding of quinone and quinol at center N of the dimeric yeast cytochrome bc1 complex. Consequences for semiquinone stabilization

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular energy utilization and molecular origin of standard metabolic rate in mammals

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of some biological pyrimidines on the succinate cycle during and after cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tricarboxylic acid cycle in rat brain synaptosomes. Fluxes and interactions with aspartate aminotransferase and malate/aspartate shuttle

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Common Mechanism Links Differently Acting Complex II Inhibitors to Cardioprotection: Modulation of Mitochondrial Reactive Oxygen Species Production

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An oxidase for reduced diphosphopyridine nucleotide

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for two sites of superoxide production by mitochondrial NADH-ubiquinone oxidoreductase (complex I).

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for succinate production by reduction of fumarate during hypoxia in isolated adult rat heart cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of pyruvate dehydrogenase in the perfused rat heart by the intracellular concentration of acetyl-coenzyme A

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrastructural localization of succinate dehydrogenase in mouse liver mitochondria; a cytochemical study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzyme-enzyme interactions as modulators of the metabolic flux through the citric acid cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble cytochrome b-c1 complex and the reconstitution of succinate-cytochrome c reductase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial complex II is essential for hypoxia-induced ROS generation and vasoconstriction in the pulmonary vasculature.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin, ketone bodies, and mitochondrial energy transduction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial metabolism of glutamine and glutamate and its physiological significance

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the succinate dehydrogenating system. Isolation and properties of the mitochondrial succinate-ubiquinone reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effect of 3-hydroxyacyl-CoAs and other long-chain fatty acidβ-oxidation intermediates on mitochondrial oxidative phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of molecular oxygen by flavins and flavoproteins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibition by 2,4-dinitrophenol of the removal of oxaloacetate formed by the oxidation of succinate by rat-liver and -heart mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic and regulatory properties of heart muscle pyruvate dehydrogenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between succinate dehydrogenase and ubiquinone-binding protein from succinate-ubiquinone reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic regulation and mathematical models

1 reference

https://pubmed.ncbi.nlm.nih.gov/21863476

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

WITHDRAWN: Oxidative stress in aging: Theoretical outcomes and clinical evidences in humans

1 reference

30 December 2023

https://opencitations.net/index/api/v1/citations/10.1016/J.BIOPHA.2010.09.010

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