Nitric oxide signaling in hypoxia (Q37986339)

26 August 2017

Nitric oxide signaling in hypoxia (English)

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26 August 2017

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J J David Ho

1

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PubMed ID

22349396

26 August 2017

H S Jeffrey Man

series ordinal

2

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PubMed ID

22349396

26 August 2017

Philip A Marsden

series ordinal

3

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26 August 2017

18 February 2012

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Journal of Molecular Medicine

26 August 2017

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26 August 2017

90

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26 August 2017

3

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26 August 2017

217-231

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https://scigraph.springernature.com/pub.10.1007/s00109-012-0880-5

26 August 2017

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cites work

Oxygen sensing, homeostasis, and disease

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Priming of hypoxia-inducible factor by neuronal nitric oxide synthase is essential for adaptive responses to severe anemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Two routes to functional adaptation: Tibetan and Andean high-altitude natives

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Higher blood flow and circulating NO products offset high-altitude hypoxia among Tibetans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Nitric oxide during altitude acclimatization

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

S-nitrosylation in cardiovascular signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Genetic evidence for high-altitude adaptation in Tibet

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

The L-arginine-nitric oxide pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Nitric oxide synthases: which, where, how, and why?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Molecular cloning and characterization of human endothelial nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Nitric oxide: a unique endogenous signaling molecule in vascular biology

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Nitric oxide in the pathogenesis of vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Oxygen-sensing under the influence of nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Oxygen, a source of life and stress

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Hypoxia-mediated regulation of gene expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Acute oxygen-sensing mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Hypoxia-inducible factors in physiology and medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Regulation of endocytosis via the oxygen-sensing pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Intermittent hypoxia degrades HIF-2alpha via calpains resulting in oxidative stress: implications for recurrent apnea-induced morbidities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Endothelial cell HIF-1α and HIF-2α differentially regulate metastatic success

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

The von Hippel-Lindau tumor suppressor protein and clear cell renal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

A conserved family of prolyl-4-hydroxylases that modify HIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Oxygen-regulated and transactivating domains in endothelial PAS protein 1: comparison with hypoxia-inducible factor-1alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

The von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

HIF hydroxylation and the mammalian oxygen-sensing pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

PHDs overactivation during chronic hypoxia "desensitizes" HIFalpha and protects cells from necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Hypoxia and cell cycle regulation of the von Hippel-Lindau tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

S-nitrosylation in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Protein S-nitrosylation: purview and parameters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

GAPDH mediates nitrosylation of nuclear proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

S-nitrosylation signaling in cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Regulation of HIF-1alpha stability through S-nitrosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

S-nitrosothiols signal hypoxia-mimetic vascular pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Studies on the reaction of nitric oxide with the hypoxia-inducible factor prolyl hydroxylase domain 2 (EGLN1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Low-molecular-weight S-nitrosothiols and blood vessel injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Endogenous S-nitrosothiols protect against myocardial injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Chemical physiology of blood flow regulation by red blood cells: the role of nitric oxide and S-nitrosohemoglobin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

S-nitrosothiols signal the ventilatory response to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Effects of regional phentolamine on hypoxic vasodilatation in healthy humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Nitric oxide-mediated vasodilation becomes independent of beta-adrenergic receptor activation with increased intensity of hypoxic exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Chronic intermittent hypoxia increases left ventricular contractility in C57BL/6J mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

β2-Adrenergics in hypoxia desensitize receptors but blunt inhibition of reabsorption in rat lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Regulation of beta-adrenergic receptor signaling by S-nitrosylation of G-protein-coupled receptor kinase 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

S-nitrosylation of beta-arrestin regulates beta-adrenergic receptor trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Oxygen sensing by HIF hydroxylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Hypoxia induces a functionally significant and translationally efficient neuronal NO synthase mRNA variant

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Translational regulation of human neuronal nitric-oxide synthase by an alternatively spliced 5'-untranslated region leader exon

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Neuronal NOS: gene structure, mRNA diversity, and functional relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

An alternative promoter of the human neuronal nitric oxide synthase gene is expressed specifically in Leydig cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Update on mechanism and catalytic regulation in the NO synthases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Nitric oxide neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

New insights into nNOS regulation of vascular homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Oxygen-dependent regulation of nitric oxide production by inducible nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Epigenetic basis for the transcriptional hyporesponsiveness of the human inducible nitric oxide synthase gene in vascular endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Epigenetic regulation of vascular endothelial gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Hypoxia-inducible Expression of a Naturalcis-Antisense Transcript Inhibits Endothelial Nitric-oxide Synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Post-transcriptional regulation of endothelial nitric-oxide synthase by an overlapping antisense mRNA transcript

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Lipopolysaccharide and interleukin 1 augment the effects of hypoxia and inflammation in human pulmonary arterial tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Pulmonary vasoconstriction and hypertension in mice with targeted disruption of the endothelial nitric oxide synthase (NOS 3) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

The pulmonary circulation of homozygous or heterozygous eNOS-null mice is hyperresponsive to mild hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Identification of hypoxia-response element in the human endothelial nitric-oxide synthase gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Relative reduction of endothelial nitric-oxide synthase expression and transcription in atherosclerosis-prone regions of the mouse aorta and in an in vitro model of disturbed flow.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Endothelial nitric oxide synthase gene expression during murine embryogenesis: commencement of expression in the embryo occurs with the establishment of a unidirectional circulatory system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Alterations in nitric oxide synthase isoform expression in NOS knockout mice exposed to normoxia or hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Subcellular targeting and differential S-nitrosylation of endothelial nitric-oxide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Receptor-regulated dynamic S-nitrosylation of endothelial nitric-oxide synthase in vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Nitric oxide and cardiopulmonary hemodynamics in Tibetan highlanders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-012-0880-5

Oxygen sensing and molecular adaptation to hypoxia

21 January 2018

1 reference

12 December 2020

Expression of multiple isoforms of nitric oxide synthase in normal and atherosclerotic vessels

1 reference

12 December 2020

Functional coupling of oxygen binding and vasoactivity in S-nitrosohemoglobin

1 reference

12 December 2020

Evolution of human hypoxia tolerance physiology

1 reference

12 December 2020

Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway

1 reference

12 December 2020

Nitric oxide synthases: regulation in disease

1 reference

12 December 2020

Physiological role of nitric oxide as an enhancer of oxygen transfer from erythrocytes to tissues

1 reference

12 December 2020

Endothelial cell regulation of nitric oxide production during hypoxia in coronary microvessels and epicardial arteries

1 reference

12 December 2020

AMP-activated protein kinase phosphorylation of endothelial NO synthase

1 reference

12 December 2020

Mechanisms of improvement in pulmonary gas exchange during isovolemic hemodilution

1 reference

12 December 2020

Maintained upregulation of pulmonary eNOS gene and protein expression during recovery from chronic hypoxia.

1 reference

12 December 2020

Protein denitrosylation: enzymatic mechanisms and cellular functions.

1 reference

12 December 2020

Diminished NO release in chronic hypoxic human endothelial cells

1 reference

12 December 2020

Nitric oxide: from discovery to the clinic

1 reference

12 December 2020

Hypoxia upregulates activity and expression of the glucose transporter GLUT1 in alveolar epithelial cells

1 reference

12 December 2020

Chronic hypoxia upregulates endothelial and inducible NO synthase gene and protein expression in rat lung

1 reference

12 December 2020

Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms

1 reference

12 December 2020

Acute and prolonged hypoxia attenuate endothelial nitric oxide production in rat pulmonary arteries by different mechanisms

1 reference

12 December 2020

eNOS-deficient mice show reduced pulmonary vascular proliferation and remodeling to chronic hypoxia

1 reference

12 December 2020

10.1007/S00109-012-0880-5

Identifiers

DOI

1 reference

26 August 2017

1 reference

PubMed ID

22349396