Mitochondrial dysfunction--a pharmacological target in Alzheimer's disease (Q38007107)

26 August 2017

Mitochondrial dysfunction--a pharmacological target in Alzheimer's disease (English)

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26 August 2017

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Gunter P Eckert

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26 August 2017

Kathrin Renner

2

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26 August 2017

Schamim H Eckert

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26 August 2017

Janett Eckmann

4

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26 August 2017

Stephanie Hagl

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26 August 2017

Reham M Abdel-Kader

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26 August 2017

Christopher Kurz

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26 August 2017

Kristina Leuner

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26 August 2017

Walter E Muller

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26 August 2017

3 May 2012

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26 August 2017

Molecular Neurobiology

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26 August 2017

46

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26 August 2017

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26 August 2017

136-150

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https://scigraph.springernature.com/pub.10.1007/s12035-012-8271-z

26 August 2017

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cites work

Mitochondrial dysfunction: common final pathway in brain aging and Alzheimer's disease--therapeutic aspects

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Thirty years of protein translocation into mitochondria: unexpectedly complex and still puzzling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Structure and function of mitochondrial carriers - role of the transmembrane helix P and G residues in the gating and transport mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

The genetics and pathology of oxidative phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

A mitochondrial protein compendium elucidates complex I disease biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondrial dynamics in mammalian health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Functions and dysfunctions of mitochondrial dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Disruption of fusion results in mitochondrial heterogeneity and dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

How mitochondria produce reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Frataxin, iron-sulfur clusters, heme, ROS, and aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Expression of mutant SOD1 in astrocytes induces functional deficits in motoneuron mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Beta-amyloid fragment 25-35 causes mitochondrial dysfunction in primary cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Ageing, oxidative stress, and mitochondrial uncoupling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Characterization of superoxide-producing sites in isolated brain mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Superoxide dismutases: role in redox signaling, vascular function, and diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondrial dysfunction, apoptotic cell death, and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Reactive oxygen species production in energized cardiac mitochondria during hypoxia/reoxygenation: modulation by nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondrial generation of free radicals and hypoxic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondrial permeability transition is a central coordinating event of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Signal transduction to the permeability transition pore.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

21 January 2018

Bcl-2 family proteins

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Critical upstream signals of cytochrome C release induced by a novel Bcl-2 inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Bcl-2 inhibitors sensitize tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by uncoupling of mitochondrial respiration in human leukemic CEM cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondrial cell death effectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

c-Jun and Bax: regulators of programmed cell death in developing neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Activation of c-Jun-N-terminal kinase and decline of mitochondrial pyruvate dehydrogenase activity during brain aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

The Bcl-2 family: roles in cell survival and oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

The mitochondria permeability transition pore complex in the brain with interacting proteins - promising targets for protection in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

What is the mitochondrial permeability transition pore?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Role of mitochondrial permeability transition pores in mitochondrial autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

The therapeutic potential of mitochondrial channels in cancer, ischemia-reperfusion injury, and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Regulation and pharmacology of the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

The identity and regulation of the mitochondrial permeability transition pore: where the known meets the unknown

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Electrophysiology of the inner mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

The mitochondrial benzodiazepine receptor: evidence for association with the voltage-dependent anion channel (VDAC)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Species- and tissue-specific relationships between mitochondrial permeability transition and generation of ROS in brain and liver mitochondria of rats and mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Shedding light on the mitochondrial permeability transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Cholesterol impairs the adenine nucleotide translocator-mediated mitochondrial permeability transition through altered membrane fluidity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

2012 Alzheimer's disease facts and figures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: implications for early mitochondrial dysfunction and oxidative damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Brain insulin signaling and Alzheimer's disease: current evidence and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondria in neuroplasticity and neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Early induction of oxidative stress in mouse model of Alzheimer disease with reduced mitochondrial superoxide dismutase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Is Alzheimer's disease a disorder of mitochondria-associated membranes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Amyloid beta-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondrial β-amyloid in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondrial permeability transition pore in Alzheimer's disease: cyclophilin D and amyloid beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Nitric oxide, mitochondria and neurological disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Protection of amyloid beta protein (25-35)-induced neurotoxicity by methanol extract of Smilacis chinae rhizome in cultured rat cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

NO synthase 2 (NOS2) deletion promotes multiple pathologies in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Current perspectives on pharmacotherapy of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: implications to mitochondria-targeted antioxidant therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Effects of polyphenols on brain ageing and Alzheimer's disease: focus on mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

21 January 2018

Dimebolin in dementia

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

A randomized, placebo-controlled trial of latrepirdine in Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Dimebon enhances hippocampus-dependent learning in both appetitive and inhibitory memory tasks in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Preclinical study of dimebon on β-amyloid-mediated neuropathology in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Cognition-enhancing properties of Dimebon in a rat novel object recognition task are unlikely to be associated with acetylcholinesterase inhibition or N-methyl-D-aspartate receptor antagonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Dimebolin is a 5-HT6 antagonist with acute cognition enhancing activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

The acute effects of dimebolin, a potential Alzheimer's disease treatment, on working memory in rhesus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Abnormal mitochondrial dynamics--a novel therapeutic target for Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondria: a therapeutic target in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Evaluation of Dimebon in cellular model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Dimebon (latrepirdine) enhances mitochondrial function and protects neuronal cells from death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Prophylaxis and reversal of ifosfamide encephalopathy with methylene-blue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Methylene blue inhibits function of the 5-HT transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

21 January 2018

Methylene blue in mania.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Behavioral and c-fos expression changes induced by nitric oxide donors microinjected into the dorsal periaqueductal gray.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Anxiolytic effect of methylene blue microinjected into the dorsal periaqueductal gray matter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Pharmacokinetic interaction of chloroquine and methylene blue combination against malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Pharmacokinetics and organ distribution of intravenous and oral methylene blue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

The effect of rotenone on respiration and its point of attack.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Memory facilitation by methylene blue: dose-dependent effect on behavior and brain oxygen consumption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Methylene blue improves brain oxidative metabolism and memory retention in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Quantitative cytochemistry of cytochrome oxidase and cellular morphometry of the human inferior colliculus in control and Alzheimer's patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Methylene blue prevents neurodegeneration caused by rotenone in the retina.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondrial dysfunction: the first domino in brain aging and Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Methylthioninium chloride reverses cognitive deficits induced by scopolamine: comparison with rivastigmine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondria as a therapeutic target for aging and neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Methylene blue as an inhibitor of superoxide generation by xanthine oxidase. A potential new drug for the attenuation of ischemia/reperfusion injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Inhibition of oxygen radical formation by methylene blue, aspirin, or alpha-lipoic acid, prevents bacterial-lipopolysaccharide-induced fever

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Stimulation of respiration by methylene blue in rat liver mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Methylene blue reduces aβ levels and rescues early cognitive deficit by increasing proteasome activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Research update: Alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Piracetam: novelty in a unique mode of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Piracetam: a review of pharmacological properties and clinical uses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Clinical efficacy of piracetam in cognitive impairment: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

SPECT monitoring of improved cerebral blood flow during long-term treatment of elderly patients with nootropic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Effect of piracetam on cerebral glucose metabolism in Alzheimer's disease as measured by positron emission tomography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

The metabolic enhancer piracetam ameliorates the impairment of mitochondrial function and neurite outgrowth induced by beta-amyloid peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Changes of the fluidity of mitochondrial membranes induced by the permeability transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Nitric oxide inhibits mitochondrial monoamine oxidase activity and decreases outer mitochondria membrane fluidity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Gradual alteration of mitochondrial structure and function by beta-amyloids: importance of membrane viscosity changes, energy deprivation, reactive oxygen species production, and cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Statins and neuroprotection: a prescription to move the field forward

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Statins: drugs for Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Simvastatin enhances learning and memory independent of amyloid load in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Age-dependent rescue by simvastatin of Alzheimer's disease cerebrovascular and memory deficits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Regulation of the brain isoprenoids farnesyl- and geranylgeranylpyrophosphate is altered in male Alzheimer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Isoprenoids, small GTPases and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Isoprenoids and related pharmacological interventions: potential application in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Chronic administration of statins alters multiple gene expression patterns in mouse cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Simvastatin protects neurons from cytotoxicity by up-regulating Bcl-2 mRNA and protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Simvastatin stimulates production of the antiapoptotic protein Bcl-2 via endothelin-1 and NFATc3 in SH-SY5Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Bcl-2 upregulation and neuroprotection in guinea pig brain following chronic simvastatin treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Effects of simvastatin on neuroprotection and modulation of Bcl-2 and BAX in the rat quinolinic acid model of Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Stabilization of mitochondrial function by Ginkgo biloba extract (EGb 761).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Biologically active secondary metabolites from Ginkgo biloba

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Effects of Ginkgo biloba in dementia: systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Effectiveness of standardized ginkgo biloba extract on cognitive symptoms of dementia with a six-month treatment: a bivariate random effect meta-analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of Alzheimer's disease and other dementias

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Ginkgo biloba for prevention of dementia: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Effects of the standardized Ginkgo biloba extract EGb 761® on neuroplasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Amyloid precursor protein metabolism is regulated toward alpha-secretase pathway by Ginkgo biloba extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Inhibition of amyloid-beta aggregation and caspase-3 activation by the Ginkgo biloba extract EGb761

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

The effects of melatonin and Ginkgo biloba extract on memory loss and choline acetyltransferase activities in the brain of rats infused intracerebroventricularly with beta-amyloid 1-40.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Plaque-derived oxidative stress mediates distorted neurite trajectories in the Alzheimer mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Prevention of age-related spatial memory deficits in a transgenic mouse model of Alzheimer's disease by chronic Ginkgo biloba treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

The promise of slow down ageing may come from curcumin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Neuroprotective and neurotrophic curcuminoids to treat stroke: a translational perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Impact of nutrition on ageing and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Alterations in mitochondrial respiratory functions, redox metabolism and apoptosis by oxidant 4-hydroxynonenal and antioxidants curcumin and melatonin in PC12 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Neuroprotective effects of the polyphenolic antioxidant agent, Curcumin, against homocysteine-induced cognitive impairment and oxidative stress in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Effect of dimethylsulphoxide and curcumin on protein carbonyls and reactive oxygen species of cerebral hemispheres of mice as a function of age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Curcuminoids modulates oxidative damage and mitochondrial dysfunction in diabetic rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

REVIEW: Curcumin and Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Challenges associated with curcumin therapy in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Omega-3 fatty acids and dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Liposome-incorporated DHA increases neuronal survival by enhancing non-amyloidogenic APP processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Update on lipids and mitochondrial function: impact of dietary n-3 polyunsaturated fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mechanisms of mitochondrial dysfunction and energy deficiency in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

The mitochondrial electron transfer alteration as a factor involved in the brain aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Mitochondrial complex I defects in aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

ROS generation, lipid peroxidation and antioxidant enzyme activities in the aging brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Plant derived omega-3-fatty acids protect mitochondrial function in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

A high linoleate and a high alpha-linolenate diet induced changes in learning behavior of rats. Effects of a shift in diets and reversal of training stimuli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Ginkgo biloba extract (EGb 761) independently improves changes in passive avoidance learning and brain membrane fluidity in the aging mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8271-Z

Ginkgo biloba extract EGb 761 protects against mitochondrial aging in the brain and in the liver.

21 January 2018

1 reference

12 December 2020

Ginkgo biloba extract (EGb761) influences monoaminergic neurotransmission via inhibition of NE uptake, but not MAO activity after chronic treatment

1 reference

12 December 2020

Mitochondrial abnormalities in neuroectodermal cells stably expressing human amyloid precursor protein (hAPP751)

1 reference

12 December 2020

Mitochondrial nitric oxide synthase

1 reference

12 December 2020

Dimebon and tacrine inhibit neurotoxic action of beta-amyloid in culture and block L-type Ca(2+) channels

1 reference

12 December 2020

Statins for the treatment of dementia

1 reference

12 December 2020

Improved mitochondrial function in brain aging and Alzheimer disease - the new mechanism of action of the old metabolic enhancer piracetam

1 reference

12 December 2020

c-Jun N-terminal kinase regulates mitochondrial bioenergetics by modulating pyruvate dehydrogenase activity in primary cortical neurons

1 reference

12 December 2020

Interactions of amyloid beta-peptide (1-40) with ganglioside-containing membranes

1 reference

12 December 2020

Gene expression and molecular composition of phospholipids in rat brain in relation to dietary n-6 to n-3 fatty acid ratio.

1 reference

12 December 2020

Piracetam reverses hippocampal membrane alterations in Alzheimer's disease

1 reference

12 December 2020

Ginkgo biloba leaf extract enhances levels of caspase-3 and amyloid precursor protein in normal rat hippocampus.

1 reference

12 December 2020

Catecholamine-induced cardiac mitochondrial dysfunction and mPTP opening: protective effect of curcumin

1 reference

12 December 2020

Dimebon ameliorates amyloid-β induced impairments of mitochondrial form and function

1 reference

12 December 2020

Energy hypometabolism in posterior cingulate cortex of Alzheimer's patients: superficial laminar cytochrome oxidase associated with disease duration.

1 reference

12 December 2020

Involvement of Bcl-2 family and caspase-3-like protease in NO-mediated neuronal apoptosis.

1 reference

12 December 2020

Antihistamine agent Dimebon as a novel neuroprotector and a cognition enhancer

1 reference

12 December 2020

Novel actions of methylene blue.

1 reference

12 December 2020

Simvastatin upregulates Bcl-2 expression and protects retinal neurons from early ischemia/reperfusion injury in the rat retina

1 reference

12 December 2020

Mitochondrial dysfunction induced by disease relevant AbetaPP and tau protein mutations.

1 reference

12 December 2020

Relationship between configuration, function, and permeability in calcium-treated mitochondria

1 reference

12 December 2020

Therapeutic potential of dietary polyphenols against brain ageing and neurodegenerative disorders

1 reference

12 December 2020

Methylene blue inhibits the function of α7-nicotinic acetylcholine receptors.

1 reference

12 December 2020

Amyloid-Beta interaction with mitochondria

1 reference

12 December 2020

Curcumin protects mitochondria from oxidative damage and attenuates apoptosis in cortical neurons.

1 reference

12 December 2020

Protective effect of curcumin (Curcuma longa) against D-galactose-induced senescence in mice

1 reference

12 December 2020

Stabilization of mitochondrial membrane potential and improvement of neuronal energy metabolism by Ginkgo biloba extract EGb 761

1 reference

12 December 2020

Mitochondria--a neglected drug target

1 reference

12 December 2020

The mitochondrial permeability transition pore as a target of cardioprotective signaling

1 reference

12 December 2020

Bcl-2 blocks loss of mitochondrial membrane potential while ICE inhibitors act at a different step during inhibition of death induced by respiratory chain inhibitors

1 reference

12 December 2020

High-linoleate and high-alpha-linolenate diets affect learning ability and natural behavior in SAMR1 mice

1 reference

12 December 2020

The action of piracetam on 14C-glucose metabolism in normal and posthypoxic rat cerebral cortex slices

1 reference

12 December 2020

Mitochondrial abnormalities in Alzheimer's disease.

1 reference

12 December 2020

10.1007/S12035-012-8271-Z

Identifiers

DOI

1 reference

Dimensions Publication ID

26 August 2017

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1 reference