Mitochondria in heart failure: the emerging role of mitochondrial dynamics (Q38019459)

27 August 2017

Mitochondria in heart failure: the emerging role of mitochondrial dynamics (English)

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27 August 2017

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José Marín-García

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27 August 2017

Alexander T Akhmedov

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2

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27 August 2017

Gordon W Moe

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27 August 2017

language of work or name

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1 July 2013

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27 August 2017

Heart Failure Reviews

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27 August 2017

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27 August 2017

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27 August 2017

439-456

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https://scigraph.springernature.com/pub.10.1007/s10741-012-9330-2

27 August 2017

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21 January 2018

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21 January 2018

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21 January 2018

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Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view

21 January 2018

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Physiological functions of mitochondrial fusion

21 January 2018

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Mitochondrial fission controls DNA fragmentation by regulating endonuclease G

21 January 2018

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Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitus

21 January 2018

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Mitochondrial inner-membrane fusion and crista maintenance requires the dynamin-related GTPase Mgm1.

21 January 2018

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Mitofusins and OPA1 mediate sequential steps in mitochondrial membrane fusion

21 January 2018

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A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy.

21 January 2018

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UGO1 encodes an outer membrane protein required for mitochondrial fusion

21 January 2018

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Disruption of fusion results in mitochondrial heterogeneity and dysfunction

21 January 2018

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OPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypes

21 January 2018

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Mutation of OPA1 causes dominant optic atrophy with external ophthalmoplegia, ataxia, deafness and multiple mitochondrial DNA deletions: a novel disorder of mtDNA maintenance.

21 January 2018

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The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells

21 January 2018

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Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

21 January 2018

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Mitochondrial fusion and fission in cell life and death

21 January 2018

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Mitochondrial dynamics and apoptosis

21 January 2018

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Cell cycle dependent morphology changes and associated mitochondrial DNA redistribution in mitochondria of human cell lines.

21 January 2018

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OPA1 links human mitochondrial genome maintenance to mtDNA replication and distribution

21 January 2018

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OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion

21 January 2018

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The Charcot-Marie-Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system

21 January 2018

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Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity

21 January 2018

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Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA

21 January 2018

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Mitochondrial oxidative phosphorylation in autosomal dominant optic atrophy

21 January 2018

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Mitochondrial bioenergetics and structural network organization

21 January 2018

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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

21 January 2018

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Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology

21 January 2018

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Differential distribution of dynamin isoforms in mammalian cells

21 January 2018

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Predominant and developmentally regulated expression of dynamin in neurons

21 January 2018

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Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits

21 January 2018

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Dynamin 3 is a component of the postsynapse, where it interacts with mGluR5 and Homer

21 January 2018

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A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis

21 January 2018

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Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA.

21 January 2018

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Cell and animal models of mtDNA biology: progress and prospects

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Regulation of mitochondrial morphology and function by O-GlcNAcylation in neonatal cardiac myocytes

21 January 2018

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Mitochondrial fusion is essential for organelle function and cardiac homeostasis

21 January 2018

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Mitochondrial fusion protects against neurodegeneration in the cerebellum.

21 January 2018

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Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations

21 January 2018

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Idiopathic Dilated Cardiomyopathy

21 January 2018

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The Genetic Basis for Cardiomyopathy

21 January 2018

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Genetics of dilated cardiomyopathy

21 January 2018

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Electron microscopic investigation of endomyocardial biopsy samples in hypertrophy and cardiomyopathy. A semiquantitative study in 48 patients

21 January 2018

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21 January 2018

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21 January 2018

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A corkscrew model for dynamin constriction.

21 January 2018

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Regulation of mitochondrial processes: a target for heart failure

21 January 2018

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Mitochondrial OPA1, apoptosis, and heart failure

21 January 2018

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Mitochondrial networking protects beta-cells from nutrient-induced apoptosis.

21 January 2018

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Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis

21 January 2018

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Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics.

21 January 2018

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Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis

21 January 2018

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Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death

21 January 2018

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The soluble form of Bax regulates mitochondrial fusion via MFN2 homotypic complexes

21 January 2018

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Mitofusin 2 triggers vascular smooth muscle cell apoptosis via mitochondrial death pathway

21 January 2018

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Mitofusin-2 is a major determinant of oxidative stress-mediated heart muscle cell apoptosis

21 January 2018

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Mitofusin 2 tethers endoplasmic reticulum to mitochondria

21 January 2018

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Activated mitofusin 2 signals mitochondrial fusion, interferes with Bax activation, and reduces susceptibility to radical induced depolarization

21 January 2018

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Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells

21 January 2018

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Mitochondria in cardiomyocyte Ca2+ signaling.

21 January 2018

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Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes

21 January 2018

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Regulation of mitochondrial fission by intracellular Ca2+ in rat ventricular myocytes

21 January 2018

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Autophagy as a protective response to Bnip3-mediated apoptotic signaling in the heart.

21 January 2018

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Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy.

21 January 2018

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Mitochondrial turnover in the heart

21 January 2018

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Dinámica mitocondrial: un potencial nuevo blanco terapéutico para la insuficiencia cardiaca

21 January 2018

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Integrative systems biology and networks in autophagy

21 January 2018

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How could Parkin-mediated ubiquitination of mitofusin promote mitophagy?

21 January 2018

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A novel member of the dynamin family of GTP-binding proteins is expressed specifically in the testis.

21 January 2018

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12 December 2020

Proteolysis of myosin and troponin in human myocardium of elderly subjects.

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12 December 2020

Mitochondrial involvement in IGF-1 induced protection of cardiomyocytes against hypoxia/reoxygenation injury

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12 December 2020

Impairment of the myocardial ultrastructure and changes of the cytoskeleton in dilated cardiomyopathy

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12 December 2020

Translocation of Bim to the endoplasmic reticulum (ER) mediates ER stress signaling for activation of caspase-12 during ER stress-induced apoptosis

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12 December 2020

Three dynamin-encoding genes are differentially expressed in developing rat brain

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12 December 2020

Assessment of secondary necrosis of Jurkat cells using a new microscopic system and double staining method with annexin V and propidium iodide

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12 December 2020

Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo

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12 December 2020

Possible division of cardiac mitochondria

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12 December 2020

Myocyte loss in chronic heart failure

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12 December 2020

Mitochondrial proliferation in cardiac hypertrophy

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12 December 2020

Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation

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12 December 2020

The bcl-2 gene product prevents programmed cell death of ventricular myocytes

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12 December 2020

The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms

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12 December 2020

Mitochondrial fragmentation in apoptosis

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12 December 2020

Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium

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12 December 2020

Formation of gigantic mitochondria in hypoxic isolated perfused rat hearts

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12 December 2020

Oxygen, oxidative stress, hypoxia, and heart failure

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12 December 2020

Apoptosis in the failing human heart

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12 December 2020

Human cells are protected from mitochondrial dysfunction by complementation of DNA products in fused mitochondria

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12 December 2020

Inhibition of autophagy in the heart induces age-related cardiomyopathy

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12 December 2020

Opa1 deficiency in a mouse model of autosomal dominant optic atrophy impairs mitochondrial morphology, optic nerve structure and visual function

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12 December 2020

Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats

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12 December 2020

Oxidative stress causes heart failure with impaired mitochondrial respiration

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12 December 2020

Apoptosis in myocytes in end-stage heart failure

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12 December 2020

Dynamin, a membrane-remodelling GTPase

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12 December 2020

10.1007/S10741-012-9330-2

Identifiers

DOI

1 reference

27 August 2017

1 reference