Mathematical optimization applications in metabolic networks (Q38048435)

27 August 2017

Mathematical optimization applications in metabolic networks (English)

1 reference

27 August 2017

Ali R Zomorrodi

1

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27 August 2017

Patrick F Suthers

series ordinal

2

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27 August 2017

Sridhar Ranganathan

series ordinal

3

1 reference

27 August 2017

Costas D Maranas

series ordinal

4

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27 August 2017

28 September 2012

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27 August 2017

Metabolic Engineering

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27 August 2017

14

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27 August 2017

672-686

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27 August 2017

6

1 reference

Metabolic flux analysis of CHO cells at growth and non-growth phases using isotopic tracers and mass spectrometry

27 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic engineering of Escherichia coli for 1-butanol production.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Directed evolution of Methanococcus jannaschii citramalate synthase for biosynthesis of 1-propanol and 1-butanol by Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic engineering for advanced biofuels production from Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

The RAST Server: rapid annotations using subsystems technology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

An automated phenotype-driven approach (GeneForce) for refining metabolic and regulatory models

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Thermodynamic constraints for biochemical networks.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Energy balance for analysis of complex metabolic networks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Recovering metabolic pathways via optimization.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Context-specific metabolic networks are consistent with experiments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Structural robustness of metabolic networks with respect to multiple knockouts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic modelling of syntrophic-like growth of a 1,3-propanediol producer, Clostridium butyricum, and a methanogenic archeon, Methanosarcina mazei, under anaerobic conditions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

MetaRoute: fast search for relevant metabolic routes for interactive network navigation and visualization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Electricity production by Geobacter sulfurreducens attached to electrodes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

A multi-tissue type genome-scale metabolic network for analysis of whole-body systems physiology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Inherited disorders of bilirubin metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Optimization-based framework for inferring and testing hypothesized metabolic objective functions.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Flux coupling analysis of genome-scale metabolic network reconstructions.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Optknock: a bilevel programming framework for identifying gene knockout strategies for microbial strain optimization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Minimal reaction sets for Escherichia coli metabolism under different growth requirements and uptake environments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

MetaCyc: a multiorganism database of metabolic pathways and enzymes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Probabilistic integrative modeling of genome-scale metabolic and regulatory networks in Escherichia coli and Mycobacterium tuberculosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Identification of optimal measurement sets for complete flux elucidation in metabolic flux analysis experiments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

In silico identification of gene amplification targets for improvement of lycopene production

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Integrating high-throughput and computational data elucidates bacterial networks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Regulation of gene expression in flux balance models of metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Rational design of ¹³C-labeling experiments for metabolic flux analysis in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Selection of tracers for 13C-metabolic flux analysis using elementary metabolite units (EMU) basis vector methodology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Primary hyperoxaluria type 1: AGT mistargeting highlights the fundamental differences between the peroxisomal and mitochondrial protein import pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic flux analysis with a comprehensive isotopomer model in Bacillus subtilis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

FFCA: a feasibility-based method for flux coupling analysis of metabolic networks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Multiple knockout analysis of genetic robustness in the yeast metabolic network

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Can single knockouts accurately single out gene functions?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

High-throughput metabolic engineering: advances in small-molecule screening and selection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Gratuitous overexpression of genes in Escherichia coli leads to growth inhibition and ribosome destruction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Reconstruction and validation of Saccharomyces cerevisiae iND750, a fully compartmentalized genome-scale metabolic model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

The University of Minnesota Biocatalysis/Biodegradation Database: the first decade

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic flux responses to pyruvate kinase knockout in Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Reconstruction of biochemical networks in microorganisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

The biomass objective function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Model-driven evaluation of the production potential for growth-coupled products of Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Fat synthesis in adipose tissue. An examination of stoichiometric constraints

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

MicrobesFlux: a web platform for drafting metabolic models from the KEGG database

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

In silico feasibility of novel biodegradation pathways for 1,2,4-trichlorobenzene.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

In silico design and adaptive evolution of Escherichia coli for production of lactic acid.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Using isotopomer path tracing to quantify metabolic fluxes in pathway models containing reversible reactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic network

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Predicting biological system objectives de novo from internal state measurements

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

PathFinder: reconstruction and dynamic visualization of metabolic pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Synthetic enhancement in gene interaction: a genetic tool come of age.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Computationally efficient flux variability analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Plasticity of genetic interactions in metabolic networks of yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Exploring the diversity of complex metabolic networks.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Thermodynamics-based metabolic flux analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

High-throughput generation, optimization and analysis of genome-scale metabolic models

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

iBsu1103: a new genome-scale metabolic model of Bacillus subtilis based on SEED annotations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Identification of genome-scale metabolic network models using experimentally measured flux profiles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Investigating the metabolic capabilities of Mycobacterium tuberculosis H37Rv using the in silico strain iNJ661 and proposing alternative drug targets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

KEGG for linking genomes to life and the environment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

From genomics to chemical genomics: new developments in KEGG

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Pathway Tools version 13.0: integrated software for pathway/genome informatics and systems biology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

A whole-cell computational model predicts phenotype from genotype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

OptORF: Optimal metabolic and regulatory perturbations for metabolic engineering of microbial strains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Large-scale bi-level strain design approaches and mixed-integer programming solution techniques

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Systematic quantification of complex metabolic flux networks using stable isotopes and mass spectrometry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Bayesian-based selection of metabolic objective functions.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

MetRxn: a knowledgebase of metabolites and reactions spanning metabolic models and databases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

GrowMatch: an automated method for reconciling in silico/in vivo growth predictions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

F2C2: a fast tool for the computation of flux coupling in genome-scale metabolic networks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Complementary identification of multiple flux distributions and multiple metabolic pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Large-scale in silico modeling of metabolic interactions between cell types in the human brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Genetic engineering of Escherichia coli for biofuel production

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Large-scale identification of genetic design strategies using local search

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Dynamic flux balance analysis of diauxic growth in Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

The effects of alternate optimal solutions in constraint-based genome-scale metabolic models

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Flux coupling analysis of metabolic networks is sensitive to missing reactions.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

On flux coupling analysis of metabolic subsystems.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

PathMiner: predicting metabolic pathways by heuristic search

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Non-linear optimization of biochemical pathways: applications to metabolic engineering and parameter estimation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

The metagenomics RAST server - a public resource for the automatic phylogenetic and functional analysis of metagenomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic network reconstruction and genome-scale model of butanol-producing strain Clostridium beijerinckii NCIMB 8052.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Connecting extracellular metabolomic measurements to intracellular flux states in yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic engineering for the microbial production of 1,3-propanediol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Algorithm for perturbing thermodynamically infeasible metabolic networks.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

The elucidation of metabolic pathways and their improvements using stable optimization of large-scale kinetic models of cellular systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Modeling Lactococcus lactis using a genome-scale flux model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Systematizing the generation of missing metabolic knowledge

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

What is flux balance analysis?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Identification of cellular objective for elucidating the physiological state of plasmid-bearing Escherichia coli using genome-scale in silico analysis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout simulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Evolutionary programming as a platform for in silico metabolic engineering

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Path finding methods accounting for stoichiometry in metabolic networks.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Exploring the overproduction of amino acids using the bilevel optimization framework OptKnock

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

OptStrain: a computational framework for redesign of microbial production systems.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

An optimization framework for identifying reaction activation/inhibition or elimination candidates for overproduction in microbial systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

An optimization model for metabolic pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

A Spatial Branch-and-Bound Framework for the Global Optimization of Kinetic Models of Metabolic Networks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Steady-state global optimization of metabolic non-linear dynamic models through recasting into power-law canonical models

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Stoichiometric model of Escherichia coli metabolism: incorporation of growth-rate dependent biomass composition and mechanistic energy requirements

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Stoichiometric network theory for nonequilibrium biochemical systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Microbial 1-butanol production: Identification of non-native production routes and in silico engineering interventions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

OptForce: an optimization procedure for identifying all genetic manipulations leading to targeted overproductions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

An integrated computational and experimental study for overproducing fatty acids in Escherichia coli.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Construction of an E. Coli genome-scale atom mapping model for MFA calculations.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Systems approach to refining genome annotation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

OptFlux: an open-source software platform for in silico metabolic engineering

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Zea mays iRS1563: a comprehensive genome-scale metabolic reconstruction of maize metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Automated design of synthetic ribosome binding sites to control protein expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Functional conservation of PAS-LuxR transcriptional regulators in polyene macrolide biosynthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Optimization based automated curation of metabolic reconstructions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Microbial production of organic acids: expanding the markets.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Network analysis of intermediary metabolism using linear optimization. I. Development of mathematical formalism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

BRENDA, the enzyme information system in 2011

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Elimination of thermodynamically infeasible loops in steady-state metabolic models

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Modeling isotopomer distributions in biochemical networks using isotopomer mapping matrices

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Quantitative analysis of metabolic fluxes in Escherichia coli, using two-dimensional NMR spectroscopy and complete isotopomer models.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Systematic evaluation of objective functions for predicting intracellular fluxes in Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic flux analysis as a tool in metabolic engineering of plants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Biomass in the manufacture of industrial products--the use of proteins and amino acids.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Analysis of optimality in natural and perturbed metabolic networks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Driving forces enable high-titer anaerobic 1-butanol synthesis in Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic engineering of Escherichia coli for 1-butanol and 1-propanol production via the keto-acid pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Regulatory on/off minimization of metabolic flux changes after genetic perturbations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Fluxomers: a new approach for 13C metabolic flux analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic engineering of Saccharomyces cerevisiae for the production of n-butanol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic modeling of a mutualistic microbial community.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic flux elucidation for large-scale models using 13C labeled isotopes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Improved computational performance of MFA using elementary metabolite units and flux coupling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Genome-scale gene/reaction essentiality and synthetic lethality analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Engineering a beta-carotene ketolase for astaxanthin production

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Predicting metabolic engineering knockout strategies for chemical production: accounting for competing pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Heterologous pyc gene expression under various natural and engineered promoters in Escherichia coli for improved succinate production.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Functional characterization of alternate optimal solutions of Escherichia coli's transcriptional and translational machinery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

A protocol for generating a high-quality genome-scale metabolic reconstruction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic flux distributions in Corynebacterium glutamicum during growth and lysine overproduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Correcting mass isotopomer distributions for naturally occurring isotopes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic capabilities of Escherichia coli: I. synthesis of biosynthetic precursors and cofactors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic engineering from a cybernetic perspective. 1. Theoretical preliminaries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic engineering from a cybernetic perspective. 2. Qualitative investigation of nodal architechtures and their response to genetic perturbation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

A computational procedure for optimal engineering interventions using kinetic models of metabolism.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Genome-scale promoter engineering by coselection MAGE

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Expression of galactose permease and pyruvate carboxylase in Escherichia coli ptsG mutant increases the growth rate and succinate yield under anaerobic conditions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Bidirectional reaction steps in metabolic networks: I. Modeling and simulation of carbon isotope labeling experiments.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

A universal framework for 13C metabolic flux analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Analysis of structural robustness of metabolic networks.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Genealogy profiling through strain improvement by using metabolic network analysis: metabolic flux genealogy of several generations of lysine-producing corynebacteria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Genome-scale metabolic network modeling results in minimal interventions that cooperatively force carbon flux towards malonyl-CoA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Ab initio prediction of thermodynamically feasible reaction directions from biochemical network stoichiometry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

EMILiO: a fast algorithm for genome-scale strain design.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic network simulation using logical loop algorithm and Jacobian matrix

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

An efficient recombination system for chromosome engineering in Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic network topology reveals transcriptional regulatory signatures of type 2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Metabolic flux analysis of Escherichia coli K12 grown on 13C-labeled acetate and glucose using GC-MS and powerful flux calculation method

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Improving the iMM904 S. cerevisiae metabolic model using essentiality and synthetic lethality data

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

OptCom: a multi-level optimization framework for the metabolic modeling and analysis of microbial communities

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

Production of beta-carotene in Zymomonas mobilis and Agrobacterium tumefaciens by introduction of the biosynthesis genes from Erwinia uredovora

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

inferred from DOI database lookup

7 January 2021

based on heuristic

Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMBEN.2012.09.005

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.YMBEN.2012.09.005

1 reference

27 August 2017

1 reference