A long journey to effective obesity treatments: is there light at the end of the tunnel? (Q38121752)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23856900%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

A long journey to effective obesity treatments: is there light at the end of the tunnel? (English)

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5 March 2020

0 references

3

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5 March 2020

Andreia J Amaral

8

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5 March 2020

Sylvia P Poulos

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5 March 2020

author name string

Michael V Dodson

1

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5 March 2020

Sihem Boudina

2

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5 March 2020

Luke Bucci

4

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5 March 2020

Melinda Fernyhough Culver

5

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5 March 2020

Shengjuan Wei

6

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5 March 2020

Werner G Bergen

7

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5 March 2020

Naima Moustaid-Moussa

9

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5 March 2020

Gary J Hausman

11

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5 March 2020

publication date

1 May 2013

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Experimental Biology and Medicine

5 March 2020

published in

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5 March 2020

volume

238

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5 March 2020

issue

5

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5 March 2020

page(s)

491-501

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Obesity: Causes and control of excess body fat.

5 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Obesity as a medical problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Managing obesity--from childhood and onwards

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Obesity pharmacotherapy: what is next?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

The "phen-pro" diet drug combination is not associated with valvular heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Organismal carbohydrate and lipid homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Effects of dietary and pharmacological manipulations on appetitive and consummatory aspects of feeding in non-human primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Board-invited review: the biology and regulation of preadipocytes and adipocytes in meat animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Signalling mechanisms regulating lipolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

The pattern of growth hormone delivery to peripheral tissues determines insulin-like growth factor-1 and lipolytic responses in obese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

What is the prognosis for new centrally-acting anti-obesity drugs?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

High-fat diet determines the composition of the murine gut microbiome independently of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

The public health impact of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Leptin at 14 y of age: an ongoing story

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Models of 'obesity' in large animals and birds

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Medical therapy for obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Antiobesity effects of the beta-cell hormone amylin in diet-induced obese rats: effects on food intake, body weight, composition, energy expenditure, and gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Leptin responsiveness restored by amylin agonism in diet-induced obesity: evidence from nonclinical and clinical studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Amylin-mediated restoration of leptin responsiveness in diet-induced obesity: magnitude and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Dynamics of fat cell turnover in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

White fat progenitor cells reside in the adipose vasculature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

In vivo identification of bipotential adipocyte progenitors recruited by β3-adrenoceptor activation and high-fat feeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Secretory factors from human adipose tissue and their functional role

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Agouti revisited: transcript quantification of the ASIP gene in bovine tissues related to protein expression and localization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

The cellular plasticity of human adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Progeny from dedifferentiated bovine adipocytes display protracted adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Establishment of a preadipocyte cell line derived from mature adipocytes of GFP transgenic mice and formation of adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

A novel preadipocyte cell line established from mouse adult mature adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Cellular and molecular comparison of redifferentiation of intramuscular- and visceral-adipocyte derived progeny cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Mature adipocytes may be a source of stem cells for tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Transplantation of mature adipocyte-derived dedifferentiated fat (DFAT) cells improves urethral sphincter contractility in a rat model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Contraction-induced myokine production and release: is skeletal muscle an endocrine organ?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Secreted proteins from adipose tissue and skeletal muscle - adipokines, myokines and adipose/muscle cross-talk

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

The origin of intermuscular adipose tissue and its pathophysiological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

High glucose induces adipogenic differentiation of muscle-derived stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Beige differentiation of adipose depots in mice lacking prolactin receptor protects against high-fat-diet-induced obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Pharmacologic management of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Increased tenascin C and Toll-like receptor 4 levels in visceral adipose tissue as a link between inflammation and extracellular matrix remodeling in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Subcutaneous adipose tissue remodeling during the initial phase of weight gain induced by overfeeding in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Overview of the effects of beta-adrenergic receptor agonists on animal growth including mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Piperine, a component of black pepper, inhibits adipogenesis by antagonizing PPARγ activity in 3T3-L1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

The effects of capsaicin and capsiate on energy balance: critical review and meta-analyses of studies in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Green tea polyphenol epigallocatechin gallate inhibits adipogenesis and induces apoptosis in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Purified berry anthocyanins but not whole berries normalize lipid parameters in mice fed an obesogenic high fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Eicosapentaenoic acid prevents and reverses insulin resistance in high-fat diet-induced obese mice via modulation of adipose tissue inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Hypothalamic malonyl-coenzyme A and the control of energy balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Role of brown adipose tissue in thermogenesis induced by overfeeding a diet containing medium chain triglyceride.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Medium-chain triglycerides are advantageous in promoting weight loss although not beneficial to exercise performance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Medium chain triglyceride oil consumption as part of a weight loss diet does not lead to an adverse metabolic profile when compared to olive oil

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Greater rise in fat oxidation with medium-chain triglyceride consumption relative to long-chain triglyceride is associated with lower initial body weight and greater loss of subcutaneous adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Medium-chain triglycerides increase energy expenditure and decrease adiposity in overweight men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

The effect of Irvingia gabonensis seeds on body weight and blood lipids of obese subjects in Cameroon

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

The use of a Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

The effects of Xanthigen in the weight management of obese premenopausal women with non-alcoholic fatty liver disease and normal liver fat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

The effect of chlorogenic acid enriched coffee on glucose absorption in healthy volunteers and its effect on body mass when used long-term in overweight and obese people

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

IGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Weight loss in type 2 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Standards of medical care in diabetes--2012

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: the BLOOM-DM study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Multicenter, placebo-controlled trial of lorcaserin for weight management

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Controlled-release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP)

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Selective deletion of leptin receptor in neurons leads to obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Leptin regulates peripheral lipid metabolism primarily through central effects on food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Disappearance of body fat in normal rats induced by adenovirus-mediated leptin gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Single intracerebroventricular bolus injection of a recombinant adenovirus expressing leptin results in reduction of food intake and body weight in both lean and obese Zucker fa/fa rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Long-term correction of obesity and diabetes in genetically obese mice by a single intramuscular injection of recombinant adeno-associated virus encoding mouse leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Transplanted hypothalamic neurons restore leptin signaling and ameliorate obesity in db/db mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

The role of the novel adipocyte-derived hormone adiponectin in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Adenovirus-mediated adiponectin expression augments skeletal muscle insulin sensitivity in male Wistar rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

AMPK as Target for Intervention in Childhood and Adolescent Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Overexpression of human adiponectin in transgenic mice results in suppression of fat accumulation and prevention of premature death by high-calorie diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Prevention of insulin resistance and diabetes in mice heterozygous for GLUT4 ablation by transgenic complementation of GLUT4 in skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Metabolic adaptations in skeletal muscle overexpressing GLUT4: effects on muscle and physical activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Adipose-specific overexpression of GLUT4 reverses insulin resistance and diabetes in mice lacking GLUT4 selectively in muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Developmental, hormonal, and nutritional regulation of porcine adipose triglyceride lipase (ATGL).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Impairment of nutritional regulation of adipose triglyceride lipase expression with age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Relative contribution of adipose triglyceride lipase and hormone-sensitive lipase to tumor necrosis factor-α (TNF-α)-induced lipolysis in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Adipose overexpression of desnutrin promotes fatty acid use and attenuates diet-induced obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Inactivation of the Fto gene protects from obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Overexpression of Fto leads to increased food intake and results in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Minireview: Pref-1: role in adipogenesis and mesenchymal cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

miR-27a is a negative regulator of adipocyte differentiation via suppressing PPARgamma expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

MicroRNA regulation in mammalian adipogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Angiopoietin-like protein 4: health effects, modulating agents and structure-function relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Cloning, chromosome mapping and expression characteristics of porcine ANGPTL3 and -4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Expression profiling analysis for genes related to meat quality and carcass traits during postnatal development of backfat in two pig breeds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Microarray gene expression profiles of fasting induced changes in liver and adipose tissues of pigs expressing the melanocortin-4 receptor D298N variant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Gene expression in hypothalamus, liver, and adipose tissues and food intake response to melanocortin-4 receptor agonist in pigs expressing melanocortin-4 receptor mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Are there still healthy obese patients?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Metabolically healthy obesity and risk of all-cause and cardiovascular disease mortality

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603

Medium- versus long-chain triglycerides for 27 days increases fat oxidation and energy expenditure without resulting in changes in body composition in overweight women

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213477603