Strategies of highly pathogenic RNA viruses to block dsRNA detection by RIG-I-like receptors: hide, mask, hit. (Q38152910)

29 August 2017

1 reference

22 August 2022

Strategies of highly pathogenic RNA viruses to block dsRNA detection by RIG-I-like receptors: hide, mask, hit. (English)

1 reference

29 August 2017

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24129118%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

author name string

Luca Zinzula

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24129118%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

language of work or name

English

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publication date

12 October 2013

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PubMed ID

24129118

29 August 2017

1 December 2013

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22 August 2022

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24129118%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

22 August 2022

100

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2 June 2020

page(s)

615-635

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2 June 2020

issue

3

1 reference

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Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein

2 June 2020

cites work

1 reference

12 December 2020

Innate immunity evasion by Dengue virus

1 reference

12 December 2020

Biochemical and immunological studies of nucleocapsid proteins of severe acute respiratory syndrome and 229E human coronaviruses

1 reference

12 December 2020

Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3'end formation of cellular pre-mRNAs

1 reference

12 December 2020

SF1 and SF2 helicases: family matters

1 reference

12 December 2020

Ebolavirus VP35 Coats the Backbone of Double-Stranded RNA for Interferon Antagonism

1 reference

12 December 2020

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

1 reference

12 December 2020

Interferon-inducible antiviral effectors

1 reference

12 December 2020

The double-stranded-RNA-binding motif: interference and much more

1 reference

12 December 2020

Flaviviruses and flavivirus vaccines

1 reference

12 December 2020

ATPase-driven oligomerization of RIG-I on RNA allows optimal activation of type-I interferon

1 reference

12 December 2020

Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus

1 reference

12 December 2020

Lassa virus nucleoprotein mutants generated by reverse genetics induce a robust type I interferon response in human dendritic cells and macrophages

1 reference

12 December 2020

Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2

1 reference

12 December 2020

Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling

1 reference

12 December 2020

A novel coronavirus associated with severe acute respiratory syndrome

1 reference

12 December 2020

Antisense transcripts in the human genome

1 reference

12 December 2020

Interferon and cytokine responses to Crimean Congo hemorrhagic fever virus; an emerging and neglected viral zonoosis

1 reference

12 December 2020

Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group

1 reference

12 December 2020

Influenza virus protein PB1-F2 inhibits the induction of type I interferon by binding to MAVS and decreasing mitochondrial membrane potential

1 reference

12 December 2020

Pathogen recognition by the innate immune system

1 reference

12 December 2020

Dengue virus targets the adaptor protein MITA to subvert host innate immunity

1 reference

12 December 2020

Ebolavirus proteins suppress the effects of small interfering RNA by direct interaction with the mammalian RNA interference pathway

1 reference

12 December 2020

A shared interface mediates paramyxovirus interference with antiviral RNA helicases MDA5 and LGP2

1 reference

12 December 2020

Influenza A virus polymerase inhibits type I interferon induction by binding to interferon beta promoter stimulator 1.

1 reference

12 December 2020

Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity

1 reference

12 December 2020

Inhibition of the type I interferon response in human dendritic cells by dengue virus infection requires a catalytically active NS2B3 complex

1 reference

12 December 2020

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

1 reference

12 December 2020

The influenza A virus protein PB1-F2: killing two birds with one stone?

1 reference

12 December 2020

West Nile virus evades activation of interferon regulatory factor 3 through RIG-I-dependent and -independent pathways without antagonizing host defense signaling

1 reference

12 December 2020

Fever with thrombocytopenia associated with a novel bunyavirus in China

1 reference

12 December 2020

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

1 reference

12 December 2020

Group 2 coronaviruses prevent immediate early interferon induction by protection of viral RNA from host cell recognition

1 reference

12 December 2020

Structural Insights into RNA Recognition by RIG-I

1 reference

12 December 2020

Hendra and Nipah viruses: different and dangerous

1 reference

12 December 2020

Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex.

1 reference

12 December 2020

Mechanism of mda-5 Inhibition by paramyxovirus V proteins.

1 reference

12 December 2020

Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling

1 reference

12 December 2020

The NY-1 hantavirus Gn cytoplasmic tail coprecipitates TRAF3 and inhibits cellular interferon responses by disrupting TBK1-TRAF3 complex formation

1 reference

12 December 2020

RIG-I and dsRNA-induced IFNbeta activation

1 reference

12 December 2020

Emergence and pandemic potential of swine-origin H1N1 influenza virus

1 reference

12 December 2020

Characterization of the Lassa virus matrix protein Z: electron microscopic study of virus-like particles and interaction with the nucleoprotein (NP).

1 reference

12 December 2020

Crystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5' triphosphate

1 reference

12 December 2020

Henipaviruses employ a multifaceted approach to evade the antiviral interferon response

1 reference

12 December 2020

Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein

1 reference

12 December 2020

Structure and function of LGP2, a DEX(D/H) helicase that regulates the innate immunity response

1 reference

12 December 2020

VISA is an adapter protein required for virus-triggered IFN-beta signaling

1 reference

12 December 2020

A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence

1 reference

12 December 2020

Analysis of adaptive mutations in Kunjin virus replicon RNA reveals a novel role for the flavivirus nonstructural protein NS2A in inhibition of beta interferon promoter-driven transcription

1 reference

12 December 2020

Pathogenesis of viral hemorrhagic fever

1 reference

12 December 2020

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

1 reference

12 December 2020

RNA binding by the novel helical domain of the influenza virus NS1 protein requires its dimer structure and a small number of specific basic amino acids

1 reference

12 December 2020

Dynamic innate immune responses of human bronchial epithelial cells to severe acute respiratory syndrome-associated coronavirus infection

1 reference

12 December 2020

Structural Analysis of a Viral Ovarian Tumor Domain Protease from the Crimean-Congo Hemorrhagic Fever Virus in Complex with Covalently Bonded Ubiquitin

1 reference

12 December 2020

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

1 reference

12 December 2020

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus

1 reference

12 December 2020

The 5' ends of Hantaan virus (Bunyaviridae) RNAs suggest a prime-and-realign mechanism for the initiation of RNA synthesis

1 reference

12 December 2020

A SAP30 complex inhibits IFN-beta expression in Rift Valley fever virus infected cells.

1 reference

12 December 2020

Evasion of interferon responses by Ebola and Marburg viruses

1 reference

12 December 2020

Poly I:C, an inducer of interferon and interference against virus infections

1 reference

12 December 2020

Evasion of influenza A viruses from innate and adaptive immune responses.

1 reference

12 December 2020

Interferon induction by viruses: one molecule of dsRNA as the threshold for interferon induction

1 reference

12 December 2020

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species

1 reference

12 December 2020

Filoviral immune evasion mechanisms

1 reference

12 December 2020

The pathogenic NY-1 hantavirus G1 cytoplasmic tail inhibits RIG-I- and TBK-1-directed interferon responses

1 reference

12 December 2020

Biophysical characterization of the complex between double-stranded RNA and the N-terminal domain of the NS1 protein from influenza A virus: evidence for a novel RNA-binding mode

1 reference

12 December 2020

The host response to West Nile Virus infection limits viral spread through the activation of the interferon regulatory factor 3 pathway

1 reference

12 December 2020

SARS coronavirus pathogenesis: host innate immune responses and viral antagonism of interferon

1 reference

12 December 2020

A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells.

1 reference

12 December 2020

Suppression of the interferon and NF-κB responses by severe fever with thrombocytopenia syndrome virus

1 reference

12 December 2020

Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

1 reference

12 December 2020

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

1 reference

12 December 2020

DENV inhibits type I IFN production in infected cells by cleaving human STING

1 reference

12 December 2020

Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia

1 reference

12 December 2020

Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus

1 reference

12 December 2020

The RIG-I-like receptor LGP2 recognizes the termini of double-stranded RNA

1 reference

12 December 2020

Viral tricks to grid-lock the type I interferon system

1 reference

12 December 2020

Negative feedback regulation of RIG-I-mediated antiviral signaling by interferon-induced ISG15 conjugation

1 reference

12 December 2020

Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppression

1 reference

12 December 2020

Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression

1 reference

12 December 2020

SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum

1 reference

12 December 2020

Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35

1 reference

12 December 2020

Multiple anti-interferon actions of the influenza A virus NS1 protein

1 reference

12 December 2020

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

1 reference

12 December 2020

Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses

1 reference

12 December 2020

Natural antisense transcripts

1 reference

12 December 2020

Molecular determinants for subcellular localization of the severe acute respiratory syndrome coronavirus open reading frame 3b protein

1 reference

12 December 2020

Mitochondrial targeting sequence of the influenza A virus PB1-F2 protein and its function in mitochondria.

1 reference

12 December 2020

The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling

1 reference

12 December 2020

SARS-CoV nucleocapsid protein antagonizes IFN-β response by targeting initial step of IFN-β induction pathway, and its C-terminal region is critical for the antagonism.

1 reference

12 December 2020

Multiple nucleic acid binding sites and intrinsic disorder of severe acute respiratory syndrome coronavirus nucleocapsid protein: implications for ribonucleocapsid protein packaging.

1 reference

12 December 2020

Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential

1 reference

12 December 2020

Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response

1 reference

12 December 2020

A novel RNA-binding motif in influenza A virus non-structural protein 1

1 reference

12 December 2020

Mouse hepatitis virus does not induce Beta interferon synthesis and does not inhibit its induction by double-stranded RNA.

1 reference

12 December 2020

Retinoic acid inducible gene-I and melanoma differentiation-associated gene 5 are induced but not essential for dengue virus induced type I interferon response

1 reference

12 December 2020

Genetic detection and characterization of Lujo virus, a new hemorrhagic fever-associated arenavirus from southern Africa

1 reference

12 December 2020

Incoming RNA virus nucleocapsids containing a 5'-triphosphorylated genome activate RIG-I and antiviral signaling

1 reference

12 December 2020

A distinct role of Riplet-mediated K63-Linked polyubiquitination of the RIG-I repressor domain in human antiviral innate immune responses

1 reference

12 December 2020

Advancements in the battle against severe acute respiratory syndrome

1 reference

12 December 2020

Transcription and RNA replication of tacaribe virus genome and antigenome analogs require N and L proteins: Z protein is an inhibitor of these processes

1 reference

12 December 2020

NSs protein of rift valley fever virus promotes posttranslational downregulation of the TFIIH subunit p62.

1 reference

12 December 2020

Cellular antiviral responses against influenza A virus are countered at the posttranscriptional level by the viral NS1A protein via its binding to a cellular protein required for the 3' end processing of cellular pre-mRNAS

1 reference

12 December 2020

Mutual antagonism between the Ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome

1 reference

12 December 2020

Structural basis for suppression of a host antiviral response by influenza A virus

1 reference

12 December 2020

The PB2 subunit of the influenza virus RNA polymerase affects virulence by interacting with the mitochondrial antiviral signaling protein and inhibiting expression of beta interferon

1 reference

12 December 2020

Differential inhibition of type I interferon induction by arenavirus nucleoproteins

1 reference

12 December 2020

X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus

1 reference

12 December 2020

Nipah and hendra virus interactions with the innate immune system

1 reference

12 December 2020

Resistance to Alpha/Beta Interferon Is a Determinant of West Nile Virus Replication Fitness and Virulence

1 reference

12 December 2020

A Single Amino Acid Substitution in the West Nile Virus Nonstructural Protein NS2A Disables Its Ability To Inhibit Alpha/Beta Interferon Induction and Attenuates Virus Virulence in Mice

1 reference

12 December 2020

TFIIH transcription factor, a target for the Rift Valley hemorrhagic fever virus.

1 reference

12 December 2020

Reverse genetic generation of recombinant Zaire Ebola viruses containing disrupted IRF-3 inhibitory domains results in attenuated virus growth in vitro and higher levels of IRF-3 activation without inhibiting viral transcription or replication

1 reference

12 December 2020

Ebola and Marburg hemorrhagic fevers: neglected tropical diseases?

1 reference

12 December 2020

Nipah virus edits its P gene at high frequency to express the V and W proteins.

1 reference

12 December 2020

Sendai virus defective-interfering genomes and the activation of interferon-beta

1 reference

12 December 2020

Structure of the Ebola VP35 interferon inhibitory domain

1 reference

12 December 2020

Influenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3'-end processing machinery

1 reference

12 December 2020

Molecular biology and genetic diversity of Rift Valley fever virus

1 reference

12 December 2020

Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease

1 reference

12 December 2020

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

1 reference

12 December 2020

The Structural Basis of 5′ Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain

1 reference

12 December 2020

Identification of multiple RIG-I-specific pathogen associated molecular patterns within the West Nile virus genome and antigenome

1 reference

12 December 2020

RIG-I detects viral genomic RNA during negative-strand RNA virus infection

1 reference

12 December 2020

Determination of the henipavirus phosphoprotein gene mRNA editing frequencies and detection of the C, V and W proteins of Nipah virus in virus-infected cells

1 reference

12 December 2020

Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferon

1 reference

12 December 2020

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

1 reference

12 December 2020

The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.

1 reference

12 December 2020

MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment

1 reference

12 December 2020

Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1

1 reference

12 December 2020

Viral counterattack against the host innate immune system

1 reference

12 December 2020

An Atomic Model of the Interferon-β Enhanceosome

1 reference

12 December 2020

ATP hydrolysis enhances RNA recognition and antiviral signal transduction by the innate immune sensor, laboratory of genetics and physiology 2 (LGP2)

1 reference

12 December 2020

Demonstration of Double-Stranded Ribonucleic Acid in Concentrates of RNA Viruses

1 reference

12 December 2020

Nucleic acid recognition by the innate immune system

1 reference

12 December 2020

Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity

1 reference

12 December 2020

Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I

1 reference

12 December 2020

H5N1 influenza viruses: outbreaks and biological properties

1 reference

12 December 2020

Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases.

1 reference

12 December 2020

Inducers of interferon and host resistance. 3. Double-stranded RNA from reovirus type 3 virions (reo 3-RNA).

1 reference

12 December 2020

Inhibition of IRF-3 activation by VP35 is critical for the high level of virulence of ebola virus

1 reference

12 December 2020

Whole-genome expression profiling reveals that inhibition of host innate immune response pathways by Ebola virus can be reversed by a single amino acid change in the VP35 protein

1 reference

12 December 2020

Mutation in murine coronavirus replication protein nsp4 alters assembly of double membrane vesicles

1 reference

12 December 2020

New developments in the induction and antiviral effectors of type I interferon

1 reference

12 December 2020

Induction and inhibition of type I interferon responses by distinct components of lymphocytic choriomeningitis virus

1 reference

12 December 2020

Composition and three-dimensional architecture of the dengue virus replication and assembly sites

1 reference

12 December 2020

A C-terminal basic amino acid motif of Zaire ebolavirus VP35 is essential for type I interferon antagonism and displays high identity with the RNA-binding domain of another interferon antagonist, the NS1 protein of influenza A virus

1 reference

12 December 2020

Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection

1 reference

12 December 2020

Inducers of interferon and host resistance. VII. Antiviral efficacy of double-stranded RNA of natural origin

1 reference

12 December 2020

Paramyxovirus V proteins interact with the RNA Helicase LGP2 to inhibit RIG-I-dependent interferon induction

1 reference

12 December 2020

Analysis of gene expression in Lassa virus-infected HuH-7 cells

1 reference

12 December 2020

Tropism of and innate immune responses to the novel human betacoronavirus lineage C virus in human ex vivo respiratory organ cultures

1 reference

12 December 2020

1 reference

12 December 2020

The influenza virus protein PB1-F2 inhibits the induction of type I interferon at the level of the MAVS adaptor protein

1 reference

12 December 2020

Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems

1 reference

12 December 2020

IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity

1 reference

12 December 2020

Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus

1 reference

12 December 2020

Poly(I)-Poly(C12U) but Not Ribavirin Prevents Death in a Hamster Model of Nipah Virus Infection

1 reference

12 December 2020

Bunyaviruses and the type I interferon system

1 reference

12 December 2020

Flavivirus induces interferon-beta gene expression through a pathway involving RIG-I-dependent IRF-3 and PI3K-dependent NF-kappaB activation

1 reference

12 December 2020

Transfectant influenza A viruses with long deletions in the NS1 protein grow efficiently in Vero cells

1 reference

12 December 2020

Hendra and Nipah viruses: why are they so deadly?

1 reference

12 December 2020

Recognition of viruses by cytoplasmic sensors

1 reference

12 December 2020

Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5

1 reference

12 December 2020

Long double-stranded RNA induces an antiviral response independent of IFN regulatory factor 3, IFN-beta promoter stimulator 1, and IFN

1 reference

12 December 2020

REPLICATIVE FORM OF ENCEPHALOMYOCARDITIS VIRUS RIBONUCLEIC ACID.

1 reference

12 December 2020

The influenza virus PB1-F2 protein has interferon antagonistic activity

1 reference

12 December 2020

Solution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptors

1 reference

12 December 2020

Identification of critical amino acids within the nucleoprotein of Tacaribe virus important for anti-interferon activity.

1 reference

12 December 2020

A single N66S mutation in the PB1-F2 protein of influenza A virus increases virulence by inhibiting the early interferon response in vivo

1 reference

12 December 2020

Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists

1 reference

12 December 2020

mda-5, but not RIG-I, is a common target for paramyxovirus V proteins.

1 reference

12 December 2020

The mitochondrial targeting chaperone 14-3-3ε regulates a RIG-I translocon that mediates membrane association and innate antiviral immunity.

1 reference

12 December 2020

The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter

1 reference

12 December 2020

Structural basis of RNA recognition and activation by innate immune receptor RIG-I

1 reference

12 December 2020

Binding of influenza A virus NS1 protein to dsRNA in vitro

1 reference

12 December 2020

NSs protein of Rift Valley fever virus blocks interferon production by inhibiting host gene transcription

1 reference

12 December 2020

Ebola and marburg hemorrhagic fever

1 reference

12 December 2020

Influenza A polymerase subunit PB2 possesses overlapping binding sites for polymerase subunit PB1 and human MAVS proteins.

1 reference

12 December 2020

The double-stranded RNA-binding motif, a versatile macromolecular docking platform

1 reference

12 December 2020

Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction

1 reference

12 December 2020

The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways

1 reference

12 December 2020

Mutations Abrogating VP35 Interaction with Double-Stranded RNA Render Ebola Virus Avirulent in Guinea Pigs

1 reference

12 December 2020

Structure of the SARS coronavirus nucleocapsid protein RNA-binding dimerization domain suggests a mechanism for helical packaging of viral RNA

1 reference

12 December 2020

Variation in the ability of human influenza A viruses to induce and inhibit the IFN-beta pathway.

1 reference

12 December 2020

The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I

1 reference

12 December 2020

Purification and functional characterization of the full length recombinant Ebola virus VP35 protein expressed in E. coli

1 reference

12 December 2020

Cap binding and immune evasion revealed by Lassa nucleoprotein structure

1 reference

12 December 2020

Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses

1 reference

12 December 2020

LGP2 plays a critical role in sensitizing mda-5 to activation by double-stranded RNA

1 reference

12 December 2020

ISG15 enhances the innate antiviral response by inhibition of IRF-3 degradation.

1 reference

12 December 2020

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

1 reference

12 December 2020

Coronaviruses post-SARS: update on replication and pathogenesis

1 reference

12 December 2020

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

1 reference

12 December 2020

Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid-inducible gene-I (RIG-I).

1 reference

12 December 2020

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

1 reference

12 December 2020

Double-stranded polynucleotides as interferon inducers

1 reference

12 December 2020

How flaviviruses activate and suppress the interferon response

1 reference

12 December 2020

Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition

1 reference

12 December 2020

Nuclear localization of the Nipah virus W protein allows for inhibition of both virus- and toll-like receptor 3-triggered signaling pathways

1 reference

12 December 2020

MDA5 assembles into a polar helical filament on dsRNA.

1 reference

12 December 2020

The cellular RNA helicase UAP56 is required for prevention of double-stranded RNA formation during influenza A virus infection

1 reference

12 December 2020

Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations

1 reference

12 December 2020

The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA

1 reference

12 December 2020

Cytosolic viral sensor RIG-I is a 5'-triphosphate-dependent translocase on double-stranded RNA.

1 reference

12 December 2020

The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.

1 reference

12 December 2020

Pathogenic flaviviruses.

1 reference

12 December 2020

Homo-oligomerization facilitates the interferon-antagonist activity of the ebolavirus VP35 protein.

1 reference

12 December 2020

Arenaviruses and hantaviruses: from epidemiology and genomics to antivirals

1 reference

12 December 2020

Dengue virus replication in infected human keratinocytes leads to activation of antiviral innate immune responses

1 reference

12 December 2020

Chapare virus, a newly discovered arenavirus isolated from a fatal hemorrhagic fever case in Bolivia

1 reference

12 December 2020

A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in mice

1 reference

12 December 2020

Conserved surface features form the double-stranded RNA binding site of non-structural protein 1 (NS1) from influenza A and B viruses

1 reference

12 December 2020

MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA

1 reference

12 December 2020

An amino-terminal polypeptide fragment of the influenza virus NS1 protein possesses specific RNA-binding activity and largely helical backbone structure.

1 reference

12 December 2020

Interferon and cytokine responses to SARS-coronavirus infection

1 reference

12 December 2020

Conventional and unconventional mechanisms for capping viral mRNA.

1 reference

12 December 2020

LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses

1 reference

12 December 2020

Hantavirus regulation of type I interferon responses

1 reference

12 December 2020

Genetic evidence for an interferon-antagonistic function of rift valley fever virus nonstructural protein NSs

1 reference

12 December 2020

Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-kappaB signaling

1 reference

12 December 2020

Crimean-Congo hemorrhagic fever virus delays activation of the innate immune response

1 reference

12 December 2020

NS1 protein of influenza A virus inhibits the function of intracytoplasmic pathogen sensor, RIG-I

1 reference

12 December 2020

The intracellular sites of early replication and budding of SARS-coronavirus

1 reference

12 December 2020

dsRNA binding characterization of full length recombinant wild type and mutants Zaire ebolavirus VP35.

1 reference

12 December 2020

Inhibition of the type I interferon response by the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus

1 reference

12 December 2020

Influenza A viruses: new research developments

1 reference

12 December 2020

Human cell tropism and innate immune system interactions of human respiratory coronavirus EMC compared to those of severe acute respiratory syndrome coronavirus

1 reference

12 December 2020

Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction

1 reference

12 December 2020

Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein

1 reference

12 December 2020

Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression

1 reference

12 December 2020

Ultrastructure and origin of membrane vesicles associated with the severe acute respiratory syndrome coronavirus replication complex

1 reference

12 December 2020

Arenavirus nucleoprotein targets interferon regulatory factor-activating kinase IKKε.

1 reference

12 December 2020

Essential role of RIG-I in the activation of endothelial cells by dengue virus

1 reference

12 December 2020

Defense against filoviruses used as biological weapons

1 reference

12 December 2020

The Ebola virus VP35 protein functions as a type I IFN antagonist.

1 reference

12 December 2020

The influenza A virus PB1-F2 protein targets the inner mitochondrial membrane via a predicted basic amphipathic helix that disrupts mitochondrial function

1 reference

12 December 2020

An emerging hemorrhagic fever in China caused by a novel bunyavirus SFTSV.

1 reference

12 December 2020

Dissociation of paramyxovirus interferon evasion activities: universal and virus-specific requirements for conserved V protein amino acids in MDA5 interference

1 reference

12 December 2020

Structural basis for Marburg virus VP35-mediated immune evasion mechanisms

1 reference

12 December 2020

Amino acid requirements for MDA5 and LGP2 recognition by paramyxovirus V proteins: a single arginine distinguishes MDA5 from RIG-I.

1 reference

12 December 2020

RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection

1 reference

12 December 2020

Dengue virus inhibits the production of type I interferon in primary human dendritic cells

1 reference

12 December 2020

Role of the virus nucleoprotein in the regulation of lymphocytic choriomeningitis virus transcription and RNA replication

1 reference

12 December 2020

Parallels among positive-strand RNA viruses, reverse-transcribing viruses and double-stranded RNA viruses

1 reference

12 December 2020

The VP35 protein of Ebola virus inhibits the antiviral effect mediated by double-stranded RNA-dependent protein kinase PKR.

1 reference

12 December 2020

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

1 reference

12 December 2020

Structural basis for dsRNA recognition by NS1 protein of influenza A virus

1 reference

12 December 2020

Identification of amino acid residues critical for the anti-interferon activity of the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus

1 reference

12 December 2020

NEMO binds ubiquitinated TANK-binding kinase 1 (TBK1) to regulate innate immune responses to RNA viruses.

1 reference

12 December 2020

The endoplasmic reticulum provides the membrane platform for biogenesis of the flavivirus replication complex

1 reference

12 December 2020

Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism

1 reference

12 December 2020

Activation of MDA5 requires higher-order RNA structures generated during virus infection

1 reference

12 December 2020

Z proteins of New World arenaviruses bind RIG-I and interfere with type I interferon induction

1 reference

12 December 2020

Recent advances in the molecular and cellular biology of bunyaviruses

1 reference

12 December 2020

The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors

1 reference

12 December 2020

A novel coronavirus capable of lethal human infections: an emerging picture

1 reference

12 December 2020

5'-Triphosphate RNA is the ligand for RIG-I

1 reference

12 December 2020

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

1 reference

12 December 2020

Junín virus infection activates the type I interferon pathway in a RIG-I-dependent manner

1 reference

12 December 2020

Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I

1 reference

12 December 2020

Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA

1 reference

12 December 2020

Linear ubiquitination of NEMO negatively regulates the interferon antiviral response through disruption of the MAVS-TRAF3 complex

1 reference

12 December 2020

Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing

1 reference

12 December 2020

Innate immunity to H5N1 influenza viruses in humans

1 reference

12 December 2020

IFNbeta induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein

1 reference

12 December 2020

RNA 3'-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex

1 reference

12 December 2020

The polymerase of negative-stranded RNA viruses

1 reference

12 December 2020

The ubiquitin ligase Riplet is essential for RIG-I-dependent innate immune responses to RNA virus infection.

1 reference

12 December 2020

Coronavirus papain-like proteases negatively regulate antiviral innate immune response through disruption of STING-mediated signaling

1 reference

12 December 2020

Tacaribe virus but not junin virus infection induces cytokine release from primary human monocytes and macrophages

1 reference

12 December 2020

Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5

1 reference

12 December 2020

Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses

1 reference

12 December 2020

Crimean-Congo hemorrhagic fever: current and future prospects of vaccines and therapies

1 reference

12 December 2020

Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains.

1 reference

12 December 2020

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

1 reference

12 December 2020

Replicon system for Lassa virus

1 reference

12 December 2020

Structural and Functional Characterization of Reston Ebola Virus VP35 Interferon Inhibitory Domain

1 reference

12 December 2020

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

1 reference

12 December 2020

Interferon-induced ISG15 pathway: an ongoing virus-host battle

1 reference

12 December 2020

The chase for the RIG-I ligand--recent advances

1 reference

12 December 2020

RNA helicase retinoic acid-inducible gene I as a sensor of Hantaan virus replication

1 reference

12 December 2020

Multifunctional nature of the arenavirus RING finger protein Z.

1 reference

12 December 2020

MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response

1 reference

12 December 2020

West Nile virus infection and immunity

1 reference

12 December 2020

Establishment and Maintenance of the Innate Antiviral Response to West Nile Virus Involves both RIG-I and MDA5 Signaling through IPS-1

1 reference

12 December 2020

Interplay between innate immunity and negative-strand RNA viruses: towards a rational model

1 reference

12 December 2020

Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery

1 reference

12 December 2020

Viral evasion and subversion of pattern-recognition receptor signalling

1 reference

12 December 2020

10.1016/J.ANTIVIRAL.2013.10.002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24129118%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24129118%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference