Cocoa phytochemicals: recent advances in molecular mechanisms on health (Q38192076)

30 August 2017

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title

Cocoa phytochemicals: recent advances in molecular mechanisms on health (English)

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30 August 2017

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5

Ki Won Lee

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30 August 2017

6

Hyong Joo Lee

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30 August 2017

Jiyoung Kim

1

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30 August 2017

Jaekyoon Kim

series ordinal

2

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30 August 2017

Jaesung Shim

series ordinal

3

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30 August 2017

Chang Yong Lee

series ordinal

4

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30 August 2017

1 January 2014

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Critical Reviews in Food Science and Nutrition

30 August 2017

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30 August 2017

54

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30 August 2017

11

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30 August 2017

1458-1472

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Uptake and metabolism of epicatechin and its access to the brain after oral ingestion

30 August 2017

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https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Flavanol and flavonol contents of cocoa powder products: influence of the manufacturing process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

The role of oxidized lipoproteins in atherogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Caffeine, diabetes, cognition, and dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Effects of long-term administration of a cocoa polyphenolic extract (Acticoa powder) on cognitive performances in aged rats

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Caffeine attenuates lipopolysaccharide-induced neuroinflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

GC-MS detection of chiral markers in cocoa beans of different quality and geographic origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Flavanols and procyanidins of cocoa and chocolate inhibit growth and polyamine biosynthesis of human colonic cancer cells

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Caffeine modulates TNF-alpha production by cord blood monocytes: the role of adenosine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Caffeine protects against disruptions of the blood-brain barrier in animal models of Alzheimer's and Parkinson's diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Cocoa procyanidins attenuate 4-hydroxynonenal-induced apoptosis of PC12 cells by directly inhibiting mitogen-activated protein kinase kinase 4 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Cocoa procyanidins protect PC12 cells from hydrogen-peroxide-induced apoptosis by inhibiting activation of p38 MAPK and JNK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Rapid reversed phase ultra-performance liquid chromatography analysis of the major cocoa polyphenols and inter-relationships of their concentrations in chocolate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Cocoa and health: a decade of research

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Cocoa and cardiovascular health

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Antioxidant effects of epicatechin on the hippocampal toxicity caused by amyloid-beta 25-35 in rats.

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Therapeutic opportunities for caffeine in Alzheimer's disease and other neurodegenerative disorders

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Transport of proanthocyanidin dimer, trimer, and polymer across monolayers of human intestinal epithelial Caco-2 cells

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Caffeine reduces TNFalpha up-regulation in human adipose tissue primary culture

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408398.2011.641041

The emerging role of flavonoid-rich cocoa and chocolate in cardiovascular health and disease

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Flavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in healthy adults.

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Caffeine as a protective factor in dementia and Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Aging and vascular responses to flavanol-rich cocoa

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Flavanol-rich cocoa induces nitric-oxide-dependent vasodilation in healthy humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Cacao polyphenolic substances. I. Fractionation of the fresh bean

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Regular consumption of a flavanol-rich chocolate can improve oxidant stress in young soccer players

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

The effect of flavanol-rich cocoa on the fMRI response to a cognitive task in healthy young people

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Cocoa polyphenols and their influence on parameters involved in ex vivo skin restructuring

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Analysis of catechins in Theobroma cacao beans by cyclodextrin-modified micellar electrokinetic chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Procyanidin and catechin contents and antioxidant capacity of cocoa and chocolate products

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Vascular effects of cocoa rich in flavan-3-ols

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Acute consumption of flavanol-rich cocoa and the reversal of endothelial dysfunction in smokers

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Endothelial function, nitric oxide, and cocoa flavanols

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Epicatechin and catechin in cocoa inhibit amyloid beta protein induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Cocoa flavanols and platelet and leukocyte function: recent in vitro and ex vivo studies in healthy adults

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Dark chocolate improves endothelial and platelet function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Aging, acculturation, salt intake, and hypertension in the Kuna of Panama.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Dark chocolate inhibits platelet aggregation in healthy volunteers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

In-vitro effects of polyphenols from cocoa and beta-sitosterol on the growth of human prostate cancer and normal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Cocoa procyanidins suppress transformation by inhibiting mitogen-activated protein kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Caffeine-mediated inhibition of calcium release channel inositol 1,4,5-trisphosphate receptor subtype 3 blocks glioblastoma invasion and extends survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Cocoa polyphenols suppress TNF-α-induced vascular endothelial growth factor expression by inhibiting phosphoinositide 3-kinase (PI3K) and mitogen-activated protein kinase kinase-1 (MEK1) activities in mouse epidermal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Effect of caffeine on the body fat and lipid metabolism of rats fed on a high-fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Myeloperoxidase/nitrite-mediated lipid peroxidation of low-density lipoprotein as modulated by flavonoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Oxidative modification of low-density lipoprotein: lipid peroxidation by myeloperoxidase in the presence of nitrite

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Cocoa polyphenols attenuate hydrogen peroxide-induced inhibition of gap-junction intercellular communication by blocking phosphorylation of connexin 43 via the MEK/ERK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Cocoa procyanidins inhibit expression and activation of MMP-2 in vascular smooth muscle cells by direct inhibition of MEK and MT1-MMP activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Cocoa has more phenolic phytochemicals and a higher antioxidant capacity than teas and red wine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Induction of cardiac fibrosis by transforming growth factor-beta(1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Caffeine protects against alcoholic liver injury by attenuating inflammatory response and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Modulation of transcription factor NF-kappaB in Hodgkin's lymphoma cell lines: effect of (-)-epicatechin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Modulation of TNF-alpha secretion in peripheral blood mononuclear cells by cocoa flavanols and procyanidins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Survey of commercially available chocolate- and cocoa-containing products in the United States. 2. Comparison of flavan-3-ol content with nonfat cocoa solids, total polyphenols, and percent cacao.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Absorption rate of methylxanthines following capsules, cola and chocolate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Cocoa consumption for 2 wk enhances insulin-mediated vasodilatation without improving blood pressure or insulin resistance in essential hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Dark chocolate consumption increases HDL cholesterol concentration and chocolate fatty acids may inhibit lipid peroxidation in healthy humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Inhibitory effects of caffeine and its metabolites on intracellular lipid accumulation in murine 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Structures of (-)-epicatechin glucuronide identified from plasma and urine after oral ingestion of (-)-epicatechin: differences between human and rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Caffeine inhibits the proliferation of liver cancer cells and activates the MEK/ERK/EGFR signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Daily cocoa intake reduces the susceptibility of low-density lipoprotein to oxidation as demonstrated in healthy human volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Influence of flavan-3-ols and procyanidins on UVC-mediated formation of 8-oxo-7,8-dihydro-2'-deoxyguanosine in isolated DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Potential therapeutic properties of green tea polyphenols in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

The effects of flavanol-rich cocoa and aspirin on ex vivo platelet function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

In vitro and in vivo effects of water extract of white cocoa tea (Camellia ptilophylla) against human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Myeloperoxidase-generated oxidants and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Effects of caffeine in Parkinson's disease: from neuroprotection to the management of motor and non-motor symptoms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Quantification of theobromine and caffeine in saliva, plasma and urine via liquid chromatography-tandem mass spectrometry: a single analytical protocol applicable to cocoa intervention studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Improved high-performance liquid chromatography method to determine theobromine and caffeine in cocoa and cocoa products

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Flavonoids from Theobroma cacao down-regulate inflammatory mediators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Cocoa: antioxidant and immunomodulator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Plasma kinetics in man of epicatechin from black chocolate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

The neuroprotective effects of caffeine: a prospective population study (the Three City Study).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Atherosclerosis — An Inflammatory Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

The effect of Malaysian cocoa extract on glucose levels and lipid profiles in diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

How do dietary flavanols improve vascular function? A position paper

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Consumption of cocoa flavanols results in acute improvements in mood and cognitive performance during sustained mental effort.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Food effects on the absorption and pharmacokinetics of cocoa flavanols

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

(-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Phenolic antioxidants attenuate neuronal cell death following uptake of oxidized low-density lipoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Chocolate at heart: the anti-inflammatory impact of cocoa flavanols

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

The anti-inflammatory properties of cocoa flavanols

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

The flavanol (-)-epicatechin prevents stroke damage through the Nrf2/HO1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Reinforcing effects of caffeine and theobromine as found in chocolate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Methylxanthines are the psycho-pharmacologically active constituents of chocolate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Effects of low doses of caffeine on cognitive performance, mood and thirst in low and higher caffeine consumers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Flavonoids and brain health: multiple effects underpinned by common mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Cocoa and chocolate flavonoids: Implications for cardiovascular health

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

The toxicology of cocoa and methylxanthines: a review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Effect of cocoa and tea intake on blood pressure: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Dietary supplementation with cacao liquor proanthocyanidins prevents elevation of blood glucose levels in diabetic obese mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Effects of acute administration of caffeine on vascular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Plant-derived flavanol (-)epicatechin enhances angiogenesis and retention of spatial memory in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Effect of dark chocolate on arterial function in healthy individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Chronic consumption of flavanol-rich cocoa improves endothelial function and decreases vascular cell adhesion molecule in hypercholesterolemic postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Antioxidants in chocolate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Anxiolytic effects of short- and long-term administration of cacao mass on rat elevated T-maze test

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Effects of cacao liquor proanthocyanidins on PhIP-induced mutagenesis in vitro, and in vivo mammary and pancreatic tumorigenesis in female Sprague-Dawley rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Chemoprevention of lung carcinogenesis by cacao liquor proanthocyanidins in a male rat multi-organ carcinogenesis model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Cacao liquor polyphenols reduce oxidative stress without maintaining alpha-tocopherol levels in rats fed a vitamin E-deficient diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Caffeine suppresses metastasis in a transgenic mouse model: a prototype molecule for prophylaxis of metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

Cacao procyanidins reduce plasma cholesterol and increase fecal steroid excretion in rats fed a high-cholesterol diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408398.2011.641041

10.1080/10408398.2011.641041

21 January 2018

Identifiers

DOI

1 reference

30 August 2017

1 reference