Lysine-targeting specificity in ubiquitin and ubiquitin-like modification pathways. (Q38201971)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24699079%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

Lysine-targeting specificity in ubiquitin and ubiquitin-like modification pathways (English)

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12 March 2020

1

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12 March 2020

Titia Sixma

series ordinal

2

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12 March 2020

author name string

Francesca Mattiroli

series ordinal

1

1 reference

30 August 2017

Titia K Sixma

series ordinal

2

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30 August 2017

publication date

1 April 2014

1 reference

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Nature Structural & Molecular Biology

12 March 2020

published in

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12 March 2020

volume

21

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12 March 2020

issue

4

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12 March 2020

page(s)

308-316

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Origin and function of ubiquitin-like proteins

12 March 2020

cites work

1 reference

RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.

21 January 2018

1 reference

RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling

21 January 2018

1 reference

Role of histone H2A ubiquitination in Polycomb silencing

21 January 2018

1 reference

Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast

21 January 2018

1 reference

FANCI is a second monoubiquitinated member of the Fanconi anemia pathway

21 January 2018

1 reference

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

21 January 2018

1 reference

Amino-terminal sequence identity of ubiquitin and the nonhistone component of nuclear protein A24

21 January 2018

1 reference

Comparative proteomic analysis identifies a role for SUMO in protein quality control

21 January 2018

1 reference

A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles

21 January 2018

1 reference

Ubiquitin - omics reveals novel networks and associations with human disease

21 January 2018

1 reference

Mass Spectrometric Analysis of Lysine Ubiquitylation Reveals Promiscuity at Site Level

21 January 2018

1 reference

Constructing and decoding unconventional ubiquitin chains.

21 January 2018

1 reference

Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling

21 January 2018

1 reference

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

21 January 2018

1 reference

RING domain E3 ubiquitin ligases

21 January 2018

1 reference

Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3

21 January 2018

1 reference

Culprits in the degradation of cyclin E apprehended

21 January 2018

1 reference

Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase

21 January 2018

1 reference

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

21 January 2018

1 reference

Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex

21 January 2018

1 reference

Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b

21 January 2018

1 reference

Function and regulation of cullin-RING ubiquitin ligases

21 January 2018

1 reference

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

21 January 2018

1 reference

21 January 2018

RBR E3-ligases at work

1 reference

Structural regulation of cullin-RING ubiquitin ligase complexes

21 January 2018

1 reference

The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation

21 January 2018

1 reference

Context of multiubiquitin chain attachment influences the rate of Sic1 degradation

21 January 2018

1 reference

Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination

21 January 2018

1 reference

How proteolysis drives the cell cycle

21 January 2018

1 reference

Control of cell growth by the SCF and APC/C ubiquitin ligases

21 January 2018

1 reference

Ubiquitination site preferences in anaphase promoting complex/cyclosome (APC/C) substrates

21 January 2018

1 reference

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

21 January 2018

1 reference

Molecular basis for lysine specificity in the yeast ubiquitin-conjugating enzyme Cdc34.

21 January 2018

1 reference

The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

21 January 2018

1 reference

Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

21 January 2018

1 reference

Critical role for lysines 21 and 22 in signal-induced, ubiquitin-mediated proteolysis of I kappa B-alpha

21 January 2018

1 reference

Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Met30)-mediated inactivation of the transcription factor Met4.

21 January 2018

1 reference

Determinants of the ubiquitin-mediated degradation of the Met4 transcription factor

21 January 2018

1 reference

A ubiquitin-interacting motif protects polyubiquitinated Met4 from degradation by the 26S proteasome

21 January 2018

1 reference

Regulation of NF-κB by ubiquitination

21 January 2018

1 reference

Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3

21 January 2018

1 reference

Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

21 January 2018

1 reference

The multiple levels of regulation by p53 ubiquitination

21 January 2018

1 reference

Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation

21 January 2018

1 reference

RNF20-RNF40: A ubiquitin-driven link between gene expression and the DNA damage response.

21 January 2018

1 reference

FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination

21 January 2018

1 reference

Ubiquitylation and the Fanconi anemia pathway

21 January 2018

1 reference

The structure of the catalytic subunit FANCL of the Fanconi anemia core complex

21 January 2018

1 reference

Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI

21 January 2018

1 reference

PCNA, the maestro of the replication fork

21 January 2018

1 reference

Mechanistic analysis of PCNA poly-ubiquitylation by the ubiquitin protein ligases Rad18 and Rad5.

21 January 2018

1 reference

A/T mutagenesis in hypermutated immunoglobulin genes strongly depends on PCNAK164 modification

21 January 2018

1 reference

E3 ligase Rad18 promotes monoubiquitination rather than ubiquitin chain formation by E2 enzyme Rad6

21 January 2018

1 reference

Intrinsic flexibility of ubiquitin on proliferating cell nuclear antigen (PCNA) in translesion synthesis.

21 January 2018

1 reference

Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing

21 January 2018

1 reference

Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation

21 January 2018

1 reference

A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase

21 January 2018

1 reference

53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark

21 January 2018

1 reference

The nucleosome acidic patch plays a critical role in RNF168-dependent ubiquitination of histone H2A.

21 January 2018

1 reference

Ubiquitin-dependent regulation of G protein-coupled receptor trafficking and signaling

21 January 2018

1 reference

Targeting of Sna3p to the endosomal pathway depends on its interaction with Rsp5p and multivesicular body sorting on its ubiquitylation

21 January 2018

1 reference

Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism

21 January 2018

1 reference

Structure of the HHARI Catalytic Domain Shows Glimpses of a HECT E3 Ligase

21 January 2018

1 reference

Structure of the human Parkin ligase domain in an autoinhibited state

21 January 2018

1 reference

Structure of parkin reveals mechanisms for ubiquitin ligase activation

21 January 2018

1 reference

Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP

21 January 2018

1 reference

TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes

21 January 2018

1 reference

Target specificity of the E3 ligase LUBAC for ubiquitin and NEMO relies on different minimal requirements.

21 January 2018

1 reference

Following Ariadne's thread: a new perspective on RBR ubiquitin ligases

21 January 2018

1 reference

Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

21 January 2018

1 reference

Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation

21 January 2018

1 reference

Identification of a physiological E2 module for the human anaphase-promoting complex

21 January 2018

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The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2

21 January 2018

1 reference

Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis

21 January 2018

1 reference

Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases.

21 January 2018

1 reference

BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer

21 January 2018

1 reference

The ubiquitin-conjugating enzyme (E2) Ube2w ubiquitinates the N terminus of substrates

21 January 2018

1 reference

Ube2W conjugates ubiquitin to α-amino groups of protein N-termini

21 January 2018

1 reference

Polyubiquitination by HECT E3s and the determinants of chain type specificity

21 January 2018

1 reference

Structure of a ubiquitin-loaded HECT ligase reveals the molecular basis for catalytic priming

21 January 2018

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LUBAC synthesizes linear ubiquitin chains via a thioester intermediate

21 January 2018

1 reference

The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension.

21 January 2018

1 reference

Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1

21 January 2018

1 reference

The small ubiquitin-like modifier-1 (SUMO-1) consensus sequence mediates Ubc9 binding and is essential for SUMO-1 modification

21 January 2018

1 reference

SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation

21 January 2018

1 reference

A molecular basis for phosphorylation-dependent SUMO conjugation by the E2 UBC9.

21 January 2018

1 reference

PDSM, a motif for phosphorylation-dependent SUMO modification

21 January 2018

1 reference

A recurrent phospho-sumoyl switch in transcriptional repression and beyond

21 January 2018

1 reference

Molecular characterization of the SUMO-1 modification of RanGAP1 and its role in nuclear envelope association

21 January 2018

1 reference

The RanBP2 SUMO E3 ligase is neither HECT- nor RING-type

21 January 2018

1 reference

Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex

21 January 2018

1 reference

The RanBP2/RanGAP1*SUMO1/Ubc9 complex is a multisubunit SUMO E3 ligase.

21 January 2018

1 reference

SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase

21 January 2018

1 reference

Structure of the Siz/PIAS SUMO E3 ligase Siz1 and determinants required for SUMO modification of PCNA

21 January 2018

1 reference

Protein group modification and synergy in the SUMO pathway as exemplified in DNA repair

21 January 2018

1 reference

Multiple domains in Siz SUMO ligases contribute to substrate selectivity.

21 January 2018

1 reference

A Dual E3 Mechanism for Rub1 Ligation to Cdc53

21 January 2018

1 reference

Dcn1 functions as a scaffold-type E3 ligase for cullin neddylation

21 January 2018

1 reference

Linkage-specific avidity defines the lysine 63-linked polyubiquitin-binding preference of rap80.

21 January 2018

1 reference

21 January 2018

1 reference

Ubiquitin-binding domains - from structures to functions

21 January 2018

1 reference

A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins

21 January 2018

1 reference

Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis

21 January 2018

1 reference

Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2

21 January 2018

1 reference

Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents

21 January 2018

1 reference

A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair

21 January 2018

1 reference

FAN1 Acts with FANCI-FANCD2 to Promote DNA Interstrand Cross-Link Repair

21 January 2018

1 reference

A new nuclease member of the FAN club

21 January 2018

1 reference

Transcriptional activation of polycomb-repressed genes by ZRF1

21 January 2018

1 reference

The HARP-like domain-containing protein AH2/ZRANB3 binds to PCNA and participates in cellular response to replication stress

21 January 2018

1 reference

ZRANB3 is a structure-specific ATP-dependent endonuclease involved in replication stress response

21 January 2018

1 reference

Polyubiquitinated PCNA recruits the ZRANB3 translocase to maintain genomic integrity after replication stress

21 January 2018

1 reference

Specification of SUMO1- and SUMO2-interacting motifs

21 January 2018

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Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p

21 January 2018

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Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2

21 January 2018

1 reference

Inhibition of homologous recombination by the PCNA-interacting protein PARI

21 January 2018

1 reference

A novel SUMO1-specific interacting motif in dipeptidyl peptidase 9 (DPP9) that is important for enzymatic regulation.

21 January 2018

1 reference

OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin

21 January 2018

1 reference

A genomic and functional inventory of deubiquitinating enzymes

21 January 2018

1 reference

K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1

21 January 2018

1 reference

OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis

21 January 2018

1 reference

Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne

21 January 2018

1 reference

Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions

21 January 2018

1 reference

Function and regulation of SUMO proteases

21 January 2018

1 reference

The COP9 signalosome: more than a protease

21 January 2018

1 reference

SUMO modification of the ubiquitin-conjugating enzyme E2-25K

21 January 2018

1 reference

Naming a targeting signal

21 January 2018

1 reference

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

31 March 2020

1 reference

A complex containing βTrCP recruits Ccd34 to catalyse ubiquitination of IκBα

31 March 2020

1 reference

The Differential Modulation of USP Activity by Internal Regulatory Domains, Interactors and Eight Ubiquitin Chain Types

31 March 2020

1 reference

A 25-kilodalton ubiquitin carrier protein (E2) catalyzes multi-ubiquitin chain synthesis via lysine 48 of ubiquitin

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24699079

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification of the Fanconi anemia complementation group I gene, FANCI.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24699079

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.2792

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24699079%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference