Metabostemness: a new cancer hallmark. (Q38261030)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325014%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

review article

1 reference

title

Metabostemness: a new cancer hallmark (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325014%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325014%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Tomas Alarcon

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325014%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

author name string

Javier A Menendez

series ordinal

1

1 reference

1 September 2017

Tomás Alarcón

series ordinal

2

1 reference

1 September 2017

29 September 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325014%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

published in

Frontiers in Oncology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325014%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325014%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

page(s)

262

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325014%20AND%20SRC:MED&resulttype=core&format=json

Defects in mitochondrial metabolism and cancer

21 February 2020

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1 reference

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Tumoral reprogramming: Plasticity takes a walk on the wild side.

6 September 2017

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Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment.

6 September 2017

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Cancer: pathological nuclear reprogramming?

6 September 2017

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6 September 2017

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The nutritional phenome of EMT-induced cancer stem-like cells

6 September 2017

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Quiescent sox2(+) cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma

6 September 2017

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Metabolic regulation of redox status in stem cells

6 September 2017

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Cancer stem cell theory and the warburg effect, two sides of the same coin?

6 September 2017

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Mathematical approaches to modeling development and reprogramming

6 September 2017

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A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect

6 September 2017

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Metabolic requirements for the maintenance of self-renewing stem cells

6 September 2017

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Dietary and metabolic control of stem cell function in physiology and cancer

6 September 2017

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Dedifferentiation and reprogramming: origins of cancer stem cells

6 September 2017

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Tumoral stem cell reprogramming as a driver of cancer: Theory, biological models, implications in cancer therapy

6 September 2017

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Gerometabolites: the pseudohypoxic aging side of cancer oncometabolites.

6 September 2017

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Circulating oncometabolite 2-hydroxyglutarate is a potential surrogate biomarker in patients with isocitrate dehydrogenase-mutant intrahepatic cholangiocarcinoma

6 September 2017

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Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling

6 September 2017

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Geroncogenesis: metabolic changes during aging as a driver of tumorigenesis

6 September 2017

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Xenopatients 2.0: reprogramming the epigenetic landscapes of patient-derived cancer genomes

6 September 2017

1 reference

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Metformin selectively targets tumor-initiating cells in ErbB2-overexpressing breast cancer models.

6 September 2017

1 reference

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MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis.

6 September 2017

1 reference

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IDH mutations in tumorigenesis and their potential role as novel therapeutic targets

6 September 2017

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Mitochondrial function in pluripotent stem cells and cellular reprogramming

6 September 2017

1 reference

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Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells

6 September 2017

1 reference

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LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7

6 September 2017

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Epigenetics and cancer metabolism

6 September 2017

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Metabolic regulation of cancer cell side population by glucose through activation of the Akt pathway.

6 September 2017

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Deterministic direct reprogramming of somatic cells to pluripotency

6 September 2017

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Tumour heterogeneity and cancer cell plasticity

6 September 2017

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Chemical approaches to stem cell biology and therapeutics

6 September 2017

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Potential applications for biguanides in oncology

6 September 2017

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Oncometabolites: linking altered metabolism with cancer

6 September 2017

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Nuclear reprogramming of luminal-like breast cancer cells generates Sox2-overexpressing cancer stem-like cellular states harboring transcriptional activation of the mTOR pathway

6 September 2017

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Metabolic regulation by p53 family members.

6 September 2017

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Mitochondrial regulation in pluripotent stem cells

6 September 2017

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Metabolome and metaboproteome remodeling in nuclear reprogramming

6 September 2017

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Serine, glycine and one-carbon units: cancer metabolism in full circle

6 September 2017

1 reference

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Rare insights into cancer biology

6 September 2017

1 reference

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Oncogenic isocitrate dehydrogenase mutations: mechanisms, models, and clinical opportunities

6 September 2017

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The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling.

6 September 2017

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Induction of Pluripotency in Mouse Somatic Cells with Lineage Specifiers

6 September 2017

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Quantitative imaging of subcellular metabolism with stable isotopes and multi-isotope imaging mass spectrometry

6 September 2017

1 reference

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Heterogeneity of tumor-induced gene expression changes in the human metabolic network

6 September 2017

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Expression of the Pluripotency Transcription Factor OCT4 in the Normal and Aberrant Mammary Gland

6 September 2017

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Epigenetic reprogramming in cancer

6 September 2017

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6 September 2017

Autophagy in stem cells

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Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer.

6 September 2017

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Small molecules, big roles -- the chemical manipulation of stem cell fate and somatic cell reprogramming

6 September 2017

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Energy metabolism and energy-sensing pathways in mammalian embryonic and adult stem cell fate

6 September 2017

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Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agents

6 September 2017

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Induction of cells with cancer stem cell properties from nontumorigenic human mammary epithelial cells by defined reprogramming factors

6 September 2017

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The mitochondrial H(+)-ATP synthase and the lipogenic switch: new core components of metabolic reprogramming in induced pluripotent stem (iPS) cells.

6 September 2017

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Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth

6 September 2017

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Metformin selectively affects human glioblastoma tumor-initiating cell viability: A role for metformin-induced inhibition of Akt.

6 September 2017

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Metformin limits the tumourigenicity of iPS cells without affecting their pluripotency

6 September 2017

1 reference

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Glioma-initiating cell elimination by metformin activation of FOXO3 via AMPK.

6 September 2017

1 reference

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Aging and reprogramming: a two-way street

6 September 2017

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Nichotherapy for stem cells: there goes the neighborhood

6 September 2017

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Metabolic plasticity in stem cell homeostasis and differentiation

6 September 2017

1 reference

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Cancer stem cell dynamics in tumor progression and metastasis: is the microenvironment to blame?

6 September 2017

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Sirtuin catalysis and regulation

6 September 2017

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An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state

6 September 2017

1 reference

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p53 and metabolism: old player in a new game

6 September 2017

1 reference

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Past, present and future of nutrigenomics and its influence on drug development

6 September 2017

1 reference

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Two-compartment tumor metabolism: autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cells

6 September 2017

1 reference

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Cancer stem cells: current status and evolving complexities

6 September 2017

1 reference

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Metformin-induced preferential killing of breast cancer initiating CD44+CD24-/low cells is sufficient to overcome primary resistance to trastuzumab in HER2+ human breast cancer xenografts

6 September 2017

1 reference

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Energy metabolism plasticity enables stemness programs

6 September 2017

1 reference

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Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells

6 September 2017

1 reference

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Metabolic reprogramming: a cancer hallmark even warburg did not anticipate

6 September 2017

1 reference

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Cancer stem cells: impact, heterogeneity, and uncertainty

6 September 2017

1 reference

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Nutrigenomics: implications for breast and colon cancer prevention

6 September 2017

1 reference

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Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells

6 September 2017

1 reference

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The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type.

6 September 2017

1 reference

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The developing cancer stem-cell model: clinical challenges and opportunities

6 September 2017

1 reference

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Multi-isotope imaging mass spectrometry quantifies stem cell division and metabolism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Metformin: multi-faceted protection against cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

The potential role of nutritional genomics tools in validating high health foods for cancer control: broccoli as example

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Metformin represses self-renewal of the human breast carcinoma stem cells via inhibition of estrogen receptor-mediated OCT4 expression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Epigenetic signatures in stem cells and cancer stem cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Energy metabolism in nuclear reprogramming

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Caveolin-1 and cancer metabolism in the tumor microenvironment: markers, models, and mechanisms

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: a roadmap from energy metabolism to stem cell renewal and aging

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Promoter hypermethylation mediated downregulation of FBP1 in human hepatocellular carcinoma and colon cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Generation of tumor-initiating cells by exogenous delivery of OCT4 transcription factor.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Glutamine synthetase is a genetic determinant of cell type-specific glutamine independence in breast epithelia

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

p53, Stem Cells, and Reprogramming: Tumor Suppression beyond Guarding the Genome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Cancer cells in epithelial-to-mesenchymal transition and tumor-propagating-cancer stem cells: distinct, overlapping or same populations

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Mammalian sirtuins and energy metabolism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Repositioning chloroquine and metformin to eliminate cancer stem cell traits in pre-malignant lesions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Hallmarks of Cancer: The Next Generation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Metabolic regulation by p53.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Inborn and acquired metabolic defects in cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Implications of cancer stem cell theory for cancer chemoprevention by natural dietary compounds

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Expression of the embryonic stem cell marker SOX2 in early-stage breast carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Transdifferentiation of glioblastoma cells into vascular endothelial cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Cells of origin in cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Identification of microRNAs regulating reprogramming factor LIN28 in embryonic stem cells and cancer cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Histone methyl transferases and demethylases; can they link metabolism and transcription?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

p53 connects tumorigenesis and reprogramming to pluripotency

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

CD44posCD49fhiCD133/2hi defines xenograft-initiating cells in estrogen receptor-negative breast cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Metformin and cancer: doses, mechanisms and the dandelion and hormetic phenomena

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Regulation of cellular metabolism by protein lysine acetylation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Rethinking the Warburg effect with Myc micromanaging glutamine metabolism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Direct cell reprogramming is a stochastic process amenable to acceleration

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Warburg effect revisited: an epigenetic link between glycolysis and gastric carcinogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

MYC-induced cancer cell energy metabolism and therapeutic opportunities

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Cancer stem cells: a reality, a myth, a fuzzy concept or a misnomer? An analysis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Energetics, epigenetics, mitochondrial genetics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Acting locally and globally: Myc's ever-expanding roles on chromatin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Systems biology of stem cell fate and cellular reprogramming

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Heterogeneity in cancer: cancer stem cells versus clonal evolution

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Suppression of induced pluripotent stem cell generation by the p53-p21 pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

The Ink4/Arf locus is a barrier for iPS cell reprogramming

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Linking the p53 tumour suppressor pathway to somatic cell reprogramming

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Lysine acetylation targets protein complexes and co-regulates major cellular functions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

ATP-citrate lyase links cellular metabolism to histone acetylation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Understanding the Warburg effect: the metabolic requirements of cell proliferation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Stem cell states, fates, and the rules of attraction

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Metabolic defects provide a spark for the epigenetic switch in cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Reprogramming cell fates: reconciling rarity with robustness

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Tumor suppressors and cell metabolism: a recipe for cancer growth

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Insulin and insulin-like growth factor signalling in neoplasia

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

The role of poly(ADP-ribosyl)ation in epigenetic events.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Tumor cell metabolism: cancer's Achilles' heel

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

The ground state of embryonic stem cell self-renewal

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

The epithelial-mesenchymal transition generates cells with properties of stem cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

p53 is regulated by the lysine demethylase LSD1

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

NAD+ metabolism in health and disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

TIGAR, a p53-inducible regulator of glycolysis and apoptosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Poly(ADP-ribose): novel functions for an old molecule

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

The biochemistry of sirtuins.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

MULTIPOTENTIALITY OF SINGLE EMBRYONAL CARCINOMA CELLS

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Prospective identification of tumorigenic breast cancer cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Stem cells, cancer, and cancer stem cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

6 September 2017

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Tumors as caricatures of the process of tissue renewal: prospects for therapy by directing differentiation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

PGC-1α, a key modulator of p53, promotes cell survival upon metabolic stress

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Developmental profile and regulation of the glycolytic enzyme hexokinase 2 in normal brain and glioblastoma multiforme

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Micro(mi)RNA expression profile of breast cancer epithelial cells treated with the anti-diabetic drug metformin: induction of the tumor suppressor miRNA let-7a and suppression of the TGFβ-induced oncomiR miRNA-181a

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Modulation of mitochondrial biogenesis and bioenergetic metabolism upon in vitro and in vivo differentiation of human ES and iPS cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Metformin against TGFβ-induced epithelial-to-mesenchymal transition (EMT): from cancer stem cells to aging-associated fibrosis.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Metformin regulates breast cancer stem cell ontogeny by transcriptional regulation of the epithelial-mesenchymal transition (EMT) status

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

The anti-diabetic drug metformin suppresses self-renewal and proliferation of trastuzumab-resistant tumor-initiating breast cancer stem cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Glucose metabolism in cancer. Evidence that demethylation events play a role in activating type II hexokinase gene expression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Spontaneous de-differentiation correlates with extended lifespan in transformed thyroid epithelial cells: an epigenetic mechanism of tumour progression?

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Metabolic regulation in pluripotent stem cells during reprogramming and self-renewal

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

A stochastic model dissects cell states in biological transition processes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Exploiting tumor metabolism: challenges for clinical translation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

The Warburg effect version 2.0: metabolic reprogramming of cancer stem cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

The emerging role of fumarate as an oncometabolite

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Metabolic regulation of epigenetics

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Mitochondrial fusion by pharmacological manipulation impedes somatic cell reprogramming to pluripotency: new insight into the role of mitophagy in cell stemness

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Mutant p53 facilitates somatic cell reprogramming and augments the malignant potential of reprogrammed cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Sox2: masterminding the root of cancer.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Transient activation of autophagy via Sox2-mediated suppression of mTOR is an important early step in reprogramming to pluripotency

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Statistical mechanics of pluripotency.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Hallmarks of cancer: of all cancer cells, all the time?

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Metformin and cancer stem cells: old drug, new targets.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Connecting threads: epigenetics and metabolism

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Clinical implications of stem cell gene Oct-4 expression in breast cancer.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Cancer stem cells, EMT, and seeding: a rose is a rose is a rose?

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Metformin and energy metabolism in breast cancer: from insulin physiology to tumour-initiating stem cells.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Embryonic stem cell markers expression in cancers.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179679

Elite and stochastic models for induced pluripotent stem cell generation

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.3389%2FFONC.2014.00262

Sox2 expression in breast tumours and activation in breast cancer stem cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25325014

12 December 2020

inferred from PubMed ID database lookup

Co-expression of Oct-4 and Nestin in human breast cancers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25325014

12 December 2020

inferred from PubMed ID database lookup

Cancer stem cells: the challenges ahead

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25325014

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.3389/FONC.2014.00262

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325014%20AND%20SRC:MED&resulttype=core&format=json

release_pao74g5nabhhjlmwpabcox7uym

21 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/pao74g5nabhhjlmwpabcox7uym

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325014%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PubMed publication ID

25325014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25325014%20AND%20SRC:MED&resulttype=core&format=json