Pathology and immune reactivity: understanding multidimensionality in pulmonary tuberculosis (Q38599692)

4 September 2017

Pathology and immune reactivity: understanding multidimensionality in pulmonary tuberculosis (English)

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4 September 2017

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Anca Dorhoi

1

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PubMed ID

26438324

4 September 2017

Stefan H E Kaufmann

series ordinal

2

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4 September 2017

5 October 2015

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Seminars in Immunopathology

4 September 2017

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4 September 2017

38

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4 September 2017

2

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4 September 2017

153-166

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https://scigraph.springernature.com/pub.10.1007/s00281-015-0531-3

4 September 2017

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Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti

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ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis

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Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids

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Early innate immunity determines outcome of Mycobacterium tuberculosis pulmonary infection in rabbits

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12 December 2020

Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

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12 December 2020

Roles of cytotoxic delayed-type hypersensitivity and macrophage-activating cell-mediated immunity in the pathogenesis of tuberculosis

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12 December 2020

Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

B cells moderate inflammatory progression and enhance bacterial containment upon pulmonary challenge with Mycobacterium tuberculosis

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Baseline predictors of sputum culture conversion in pulmonary tuberculosis: importance of cavities, smoking, time to detection and W-Beijing genotype

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12 December 2020

Local immune responses correlate with presentation and outcome in tuberculosis

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12 December 2020

Mycobacterium tuberculosis inhibits neutrophil apoptosis, leading to delayed activation of naive CD4 T cells

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12 December 2020

Biomarkers of inflammation, immunosuppression and stress with active disease are revealed by metabolomic profiling of tuberculosis patients

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12 December 2020

Exogenous reinfection in tuberculosis

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12 December 2020

Clinical and radiographic correlates of primary and reactivation tuberculosis: a molecular epidemiology study.

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12 December 2020

Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent

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12 December 2020

The time-table of tuberculosis

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12 December 2020

Novel regimens identified in mice for treatment of latent tuberculosis infection in contacts of patients with multidrug-resistant tuberculosis

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12 December 2020

S100A8/A9 proteins mediate neutrophilic inflammation and lung pathology during tuberculosis

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12 December 2020

A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis.

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12 December 2020

Expression of many immunologically important genes in Mycobacterium tuberculosis-infected macrophages is independent of both TLR2 and TLR4 but dependent on IFN-alphabeta receptor and STAT1.

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12 December 2020

Trafficking of superinfecting Mycobacterium organisms into established granulomas occurs in mammals and is independent of the Erp and ESX-1 mycobacterial virulence loci

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12 December 2020

Granuloma formation and host defense in chronic Mycobacterium tuberculosis infection requires PYCARD/ASC but not NLRP3 or caspase-1.

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12 December 2020

The formation of the granuloma in tuberculosis infection

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12 December 2020

Granzyme B-expressing neutrophils correlate with bacterial load in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques

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12 December 2020

Arginase-1 expression in granulomas of tuberculosis patients.

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12 December 2020

Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis

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12 December 2020

The key role of exudative lesions and their encapsulation: lessons learned from the pathology of human pulmonary tuberculosis

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12 December 2020

Innate and adaptive interferons suppress IL-1α and IL-1β production by distinct pulmonary myeloid subsets during Mycobacterium tuberculosis infection

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12 December 2020

Cell wall lipids from Mycobacterium bovis BCG are inflammatory when inoculated within a gel matrix: characterization of a new model of the granulomatous response to mycobacterial components.

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12 December 2020

Presence of multiple lesion types with vastly different microenvironments in C3HeB/FeJ mice following aerosol infection with Mycobacterium tuberculosis.

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12 December 2020

Transcriptional reprogramming in nonhuman primate (rhesus macaque) tuberculosis granulomas

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12 December 2020

Lung-residing myeloid-derived suppressors display dual functionality in murine pulmonary tuberculosis

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12 December 2020

Adventures within the speckled band: heterogeneity, angiogenesis, and balanced inflammation in the tuberculous granuloma.

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12 December 2020

The immune response in tuberculosis

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12 December 2020

iNKT cell production of GM-CSF controls Mycobacterium tuberculosis.

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12 December 2020

Soluble TNFRp75 regulates host protective immunity against Mycobacterium tuberculosis

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12 December 2020

Induced sputum MMP-1, -3 & -8 concentrations during treatment of tuberculosis

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12 December 2020

Lung remodeling in pulmonary tuberculosis

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12 December 2020

γδ T cells cross-link innate and adaptive immunity in Mycobacterium tuberculosis infection.

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12 December 2020

Mycobacterium tuberculosis and the intimate discourse of a chronic infection

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12 December 2020

A new vaccine against tuberculosis affords greater survival after challenge than the current vaccine in the guinea pig model of pulmonary tuberculosis

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12 December 2020

Contact investigation for tuberculosis: a systematic review and meta-analysis.

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12 December 2020

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

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12 December 2020

Differences in mannose receptor-mediated uptake of lipoarabinomannan from virulent and attenuated strains of Mycobacterium tuberculosis by human macrophages

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12 December 2020

Mycobacterium tuberculosis: success through dormancy

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12 December 2020

Macrophage phagocytosis of virulent but not attenuated strains of Mycobacterium tuberculosis is mediated by mannose receptors in addition to complement receptors

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12 December 2020

NALP3 is not necessary for early protection against experimental tuberculosis.

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12 December 2020

Platelets direct monocyte differentiation into epithelioid-like multinucleated giant foam cells with suppressive capacity upon mycobacterial stimulation

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12 December 2020

Noninvasive pulmonary [18F]-2-fluoro-deoxy-D-glucose positron emission tomography correlates with bactericidal activity of tuberculosis drug treatment

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12 December 2020

Exogenous reinfection and pulmonary tuberculosis a study of the pathology

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12 December 2020

Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population

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12 December 2020

Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection

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12 December 2020

Profiling early lung immune responses in the mouse model of tuberculosis

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12 December 2020

Rifapentine and isoniazid once a week versus rifampicin and isoniazid twice a week for treatment of drug-susceptible pulmonary tuberculosis in HIV-negative patients: a randomised clinical trial

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12 December 2020

The cellular immune response to Mycobacterium tuberculosis infection in the guinea pig.

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12 December 2020

Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization

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12 December 2020

Heterogeneity in tuberculosis pathology, microenvironments and therapeutic responses

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12 December 2020

Dissemination of Mycobacterium tuberculosis is influenced by host factors and precedes the initiation of T-cell immunity.

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12 December 2020

Human tuberculous granulomas induce peripheral lymphoid follicle-like structures to orchestrate local host defence in the lung.

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12 December 2020

Versatile myeloid cell subsets contribute to tuberculosis-associated inflammation

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12 December 2020

NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

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12 December 2020

Trehalose 6,6'-dimycolate (cord factor) of Mycobacterium tuberculosis induces foreign-body- and hypersensitivity-type granulomas in mice

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12 December 2020

Increased frequency of myeloid-derived suppressor cells during active tuberculosis and after recent mycobacterium tuberculosis infection suppresses T-cell function

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12 December 2020

Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas.

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12 December 2020

Type I IFN signaling triggers immunopathology in tuberculosis-susceptible mice by modulating lung phagocyte dynamics

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12 December 2020

Mathematical modeling of tuberculosis bacillary counts and cellular populations in the organs of infected mice.

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12 December 2020

Response of cultured macrophages to Mycobacterium tuberculosis, with observations on fusion of lysosomes with phagosomes

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12 December 2020

Dectin-2 is a direct receptor for mannose-capped lipoarabinomannan of mycobacteria

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12 December 2020

Procollagen III N-terminal propeptide and desmosine are released by matrix destruction in pulmonary tuberculosis

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12 December 2020

Interleukin 27R regulates CD4+ T cell phenotype and impacts protective immunity during Mycobacterium tuberculosis infection

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12 December 2020

Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death

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12 December 2020

Differential organization of the local immune response in patients with active cavitary tuberculosis or with nonprogressive tuberculoma.

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12 December 2020

Mycobacterium tuberculosis growth at the cavity surface: a microenvironment with failed immunity

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12 December 2020

Double-phase 18F-FDG PET-CT for determination of pulmonary tuberculoma activity

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12 December 2020

Anti-vascular endothelial growth factor treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery

1 reference

12 December 2020

Allele-specific induction of IL-1β expression by C/EBPβ and PU.1 contributes to increased tuberculosis susceptibility

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12 December 2020

MicroRNA-223 controls susceptibility to tuberculosis by regulating lung neutrophil recruitment

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12 December 2020

A matrix metalloproteinase inhibitor promotes granuloma formation during the early phase of Mycobacterium tuberculosis pulmonary infection

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12 December 2020

Local immune responses in human tuberculosis: learning from the site of infection

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12 December 2020

Macrophages play a dual role during pulmonary tuberculosis in mice

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12 December 2020

Characterization of the tuberculous granuloma in murine and human lungs: cellular composition and relative tissue oxygen tension

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12 December 2020

Bacillary replication and macrophage necrosis are determinants of neutrophil recruitment in tuberculosis

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12 December 2020

Tuberculosis and granuloma formation in patients receiving anti-TNF therapy

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12 December 2020

Macrophage and T cell dynamics during the development and disintegration of mycobacterial granulomas

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12 December 2020

Genetically determined susceptibility to tuberculosis in mice causally involves accelerated and enhanced recruitment of granulocytes

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12 December 2020

Trehalose 6,6'-dimycolate and lipid in the pathogenesis of caseating granulomas of tuberculosis in mice.

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12 December 2020

Neutrophil granules in health and disease

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12 December 2020

Mycobacterium tuberculosis keto-mycolic acid and macrophage nuclear receptor TR4 modulate foamy biogenesis in granulomas: a case of a heterologous and noncanonical ligand-receptor pair

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12 December 2020

Essential yet limited role for CCR2⁺ inflammatory monocytes during Mycobacterium tuberculosis-specific T cell priming

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12 December 2020

Mycobacterium tuberculosis up-regulates matrix metalloproteinase-1 secretion from human airway epithelial cells via a p38 MAPK switch

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12 December 2020

Cell-autonomous effector mechanisms against mycobacterium tuberculosis

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12 December 2020

Cytosolic access of Mycobacterium tuberculosis: critical impact of phagosomal acidification control and demonstration of occurrence in vivo

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12 December 2020

Mycobacterial lipomannan induces granuloma macrophage fusion via a TLR2-dependent, ADAM9- and beta1 integrin-mediated pathway

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12 December 2020

Inflammatory dendritic cells migrate in and out of transplanted chronic mycobacterial granulomas in mice

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12 December 2020

Cattle as a model for development of vaccines against human tuberculosis.

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12 December 2020

10.1007/S00281-015-0531-3

Identifiers

DOI

1 reference

PubMed ID

26438324

Dimensions Publication ID

4 September 2017

0 references

1 reference

PubMed ID

26438324