Matters of context guide future research in TGFβ superfamily signaling (Q38612468)

4 September 2017

Matters of context guide future research in TGFβ superfamily signaling (English)

1 reference

4 September 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486175%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

author name string

Richard W Padgett

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486175%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

publication date

20 October 2015

1 reference

4 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486175%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486175%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

issue

399

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486175%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

page(s)

re10

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The Trichoplax genome and the nature of placozoans

5 June 2020

cites work

1 reference

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The Amphimedon queenslandica genome and the evolution of animal complexity

21 January 2018

1 reference

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Emergence, development and diversification of the TGF-beta signalling pathway within the animal kingdom

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

The RNA binding protein quaking regulates formation of circRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

TRAF6 promotes TGFβ-induced invasion and cell-cycle regulation via Lys63-linked polyubiquitination of Lys178 in TGFβ type I receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

TRAF6 stimulates the tumor-promoting effects of TGFβ type I receptor through polyubiquitination and activation of presenilin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Cytoneme-mediated contact-dependent transport of the Drosophila decapentaplegic signaling protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Paracrine signaling mediated at cell-cell contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

EMBRYO DEVELOPMENT. BMP gradients: A paradigm for morphogen-mediated developmental patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Myoblast cytonemes mediate Wg signaling from the wing imaginal disc and Delta-Notch signaling to the air sac primordium

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Cytonemes: cellular processes that project to the principal signaling center in Drosophila imaginal discs

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Cytonemes are required for the establishment of a normal Hedgehog morphogen gradient in Drosophila epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Exosomes as Hedgehog carriers in cytoneme-mediated transport and secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Dynamic association with donor cell filopodia and lipid-modification are essential features of Wnt8a during patterning of the zebrafish neuroectoderm

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Chordin is required for the Spemann organizer transplantation phenomenon in Xenopus embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Mad linker phosphorylations control the intensity and range of the BMP-activity gradient in developing Drosophila tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Cyclin-dependent kinases regulate the antiproliferative function of Smads

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Cleavages within the prodomain direct intracellular trafficking and degradation of mature bone morphogenetic protein-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Regulation of bone morphogenetic protein-4 activity by sequence elements within the prodomain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

A large bioactive BMP ligand with distinct signaling properties is produced by alternative proconvertase processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Transforming growth factor beta receptor signaling and endocytosis are linked through a COOH terminal activation motif in the type I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Transforming growth factor beta activates Smad2 in the absence of receptor endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Regulation of TGF-β receptor hetero-oligomerization and signaling by endoglin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Internalization-dependent and -independent requirements for transforming growth factor beta receptor signaling via the Smad pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

BMP signaling requires retromer-dependent recycling of the type I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

A global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Internalization of the TGF-β type I receptor into caveolin-1 and EEA1 double-positive early endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Promotion of bone morphogenetic protein signaling by tetraspanins and glycosphingolipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Genetic screen for small body size mutants in C. elegans reveals many TGFbeta pathway components

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Caenorhabditis elegans SMA-10/LRIG is a conserved transmembrane protein that enhances bone morphogenetic protein signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

The RGM protein DRAG-1 positively regulates a BMP-like signaling pathway in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

The neogenin/DCC homolog UNC-40 promotes BMP signaling via the RGM protein DRAG-1 in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

CIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Essential role of TGF-beta signaling in glucose-induced cell hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

The insulin response integrates increased TGF-β signaling through Akt-induced enhancement of cell surface delivery of TGF-β receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Crimpy enables discrimination of presynaptic and postsynaptic pools of a BMP at the Drosophila neuromuscular junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Crimpy inhibits the BMP homolog Gbb in motoneurons to enable proper growth control at the Drosophila neuromuscular junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

CRIM1 regulates the rate of processing and delivery of bone morphogenetic proteins to the cell surface.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Postsynaptic glutamate receptors regulate local BMP signaling at the Drosophila neuromuscular junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Characterization of the activation of latent TGF-beta by co-cultures of endothelial cells and pericytes or smooth muscle cells: a self-regulating system

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Latent TGF-β structure and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Structure of bone morphogenetic protein 9 procomplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Structural determinants of integrin β-subunit specificity for latent TGF-β.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Redox-mediated activation of latent transforming growth factor-beta 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Transforming growth factor-beta activation in irradiated murine mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Latent transforming growth factor-beta: structural features and mechanisms of activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

A method to recapitulate early embryonic spatial patterning in human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Cell density sensing alters TGF-β signaling in a cell-type-specific manner, independent from Hippo pathway activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Distinct polarity cues direct Taz/Yap and TGFβ receptor localization to differentially control TGFβ-induced Smad signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Switch enhancers interpret TGF-β and Hippo signaling to control cell fate in human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Differential topical susceptibility to TGFβ in intact and injured regions of the epithelium: key role in myofibroblast transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

BMP9 and BMP10 are necessary for proper closure of the ductus arteriosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

EndMT contributes to the onset and progression of cerebral cavernous malformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Tead2 expression levels control the subcellular distribution of Yap and Taz, zyxin expression and epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Ski regulates Hippo and TAZ signaling to suppress breast cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Endogenous human microRNAs that suppress breast cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Klf4 is a transcriptional regulator of genes critical for EMT, including Jnk1 (Mapk8).

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Network-Based Approaches to Understand the Roles of miR-200 and Other microRNAs in Cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

TGF-β promotes heterogeneity and drug resistance in squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

NR2F1 controls tumour cell dormancy via SOX9- and RARβ-driven quiescence programmes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

ACVR1R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

An anti-transforming growth factor beta antibody suppresses metastasis via cooperative effects on multiple cell compartments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

The type III TGF-beta receptor suppresses breast cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

TβRIII independently binds type I and type II TGF-β receptors to inhibit TGF-β signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Type III TGF-β receptor downregulation generates an immunotolerant tumor microenvironment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Cutaneous keratoacanthomas/squamous cell carcinomas associated with neutralization of transforming growth factor β by the monoclonal antibody fresolimumab (GC1008).

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Phase I study of GC1008 (fresolimumab): a human anti-transforming growth factor-beta (TGFβ) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

The αvβ1 integrin plays a critical in vivo role in tissue fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Membrane protein GARP is a receptor for latent TGF-beta on the surface of activated human Treg

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Release of active TGF-β1 from the latent TGF-β1/GARP complex on T regulatory cells is mediated by integrin β8

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Safety, pharmacokinetics, pharmacodynamics, and antitumor activity of dalantercept, an activin receptor-like kinase-1 ligand trap, in patients with advanced cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Endothelial ALK1 Is a Therapeutic Target to Block Metastatic Dissemination of Breast Cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Transforming growth factor-β superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Association of growth differentiation factor 11/8, putative anti-ageing factor, with cardiovascular outcomes and overall mortality in humans: analysis of the Heart and Soul and HUNT3 cohorts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Vascular and neurogenic rejuvenation of the aging mouse brain by young systemic factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Regenerative medicine. 'Rejuvenating' protein doubted.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Autocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Inhibition of BMP signaling suppresses metastasis in mammary cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Small molecule inhibitor of the bone morphogenetic protein pathway DMH1 reduces ovarian cancer cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Beyond TGFβ: roles of other TGFβ superfamily members in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Noncanonical TGFβ signaling contributes to aortic aneurysm progression in Marfan syndrome mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Effective chemoimmunotherapy with anti-TGFβ antibody and cyclophosphamide in a mouse model of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

A multigenic program mediating breast cancer metastasis to bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

Genetic variants of Adam17 differentially regulate TGFβ signaling to modify vascular pathology in mice and humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

TGF-β signalling-related markers in cancer patients with bone metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAD0416

10.1126/SCISIGNAL.AAD0416

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26486175%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference