Tackling myocardial ischemic injury: the signal transducer and activator of transcription 3 (STAT3) at a good site (Q39046345)

8 September 2017

title

Tackling myocardial ischemic injury: the signal transducer and activator of transcription 3 (STAT3) at a good site (English)

1 reference

8 September 2017

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28001439%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Shouyin Di

3

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8 June 2020

Zhiqiang Ma

4

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8 June 2020

author name string

Yang Yang

1

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8 June 2020

Wei Hu

2

1 reference

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8 June 2020

Chongxi Fan

5

1 reference

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8 June 2020

Dongjin Wang

6

1 reference

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8 June 2020

Yue Li

8

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8 June 2020

Qing Zhou

9

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8 June 2020

Tian Li

10

1 reference

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8 June 2020

Erping Luo

11

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8 June 2020

language of work or name

English

0 references

publication date

21 December 2016

1 reference

Expert Opinion on Therapeutic Targets

8 September 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28001439%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

21

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8 June 2020

issue

2

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8 June 2020

page(s)

215-228

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Myocardial reperfusion injury.

8 June 2020

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STAT transcription in the ischemic heart

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Multiple roles of STAT3 in cardiovascular inflammatory responses

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21 January 2018

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Understanding STAT3 signaling in cardiac ischemia.

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Across-Species Transfer of Protection by Remote Ischemic Preconditioning With Species-Specific Myocardial Signal Transduction by Reperfusion Injury Salvage Kinase and Survival Activating Factor Enhancement Pathways

21 January 2018

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Survival pathways in hypertrophy and heart failure: the gp130-STAT3 axis

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The JAK-STAT pathway: impact on human disease and therapeutic intervention

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The emerging role of signal transducer and activator of transcription 3 in cerebral ischemic and hemorrhagic stroke

21 January 2018

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STATs in cancer inflammation and immunity: a leading role for STAT3

21 January 2018

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Disruption of mammalian target of rapamycin complex 1 in macrophages decreases chemokine gene expression and atherosclerosis

21 January 2018

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H11 kinase/heat shock protein 22 deletion impairs both nuclear and mitochondrial functions of STAT3 and accelerates the transition into heart failure on cardiac overload

21 January 2018

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Interleukin-10 treatment attenuates pressure overload-induced hypertrophic remodeling and improves heart function via signal transducers and activators of transcription 3-dependent inhibition of nuclear factor-κB

21 January 2018

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Interleukin-27, a novel cytokine induced by ischemia-reperfusion injury in rat hearts, mediates cardioprotective effects via the gp130/STAT3 pathway.

21 January 2018

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Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling

21 January 2018

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STAT3, a key regulator of cell-to-cell communication in the heart

21 January 2018

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Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel

21 January 2018

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Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T

21 January 2018

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Cardiac preconditioning with sphingosine-1-phosphate requires activation of signal transducer and activator of transcription-3.

21 January 2018

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Dancing rhinos in stilettos: The amazing saga of the genomic and nongenomic actions of STAT3 in the heart

21 January 2018

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Identification of novel direct Stat3 target genes for control of growth and differentiation

21 January 2018

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Gene delivery of suppressors of cytokine signaling (SOCS) inhibits inflammation and atherosclerosis development in mice

21 January 2018

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Mechanisms of sex differences in TNFR2-mediated cardioprotection

21 January 2018

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Both endogenous and exogenous testosterone decrease myocardial STAT3 activation and SOCS3 expression after acute ischemia and reperfusion.

21 January 2018

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SOCS1 gene transfer accelerates the transition to heart failure through the inhibition of the gp130/JAK/STAT pathway

21 January 2018

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SOCS3: A novel therapeutic target for cardioprotection

21 January 2018

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Cardiac-specific deletion of SOCS-3 prevents development of left ventricular remodeling after acute myocardial infarction

21 January 2018

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Regulation of JAK/STAT signalling by SOCS in the myocardium.

21 January 2018

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SOCS proteins, cytokine signalling and immune regulation

21 January 2018

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JAK2/STAT3 activation by melatonin attenuates the mitochondrial oxidative damage induced by myocardial ischemia/reperfusion injury

21 January 2018

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S-propargyl-cysteine, a novel water-soluble modulator of endogenous hydrogen sulfide, promotes angiogenesis through activation of signal transducer and activator of transcription 3.

21 January 2018

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Therapeutic activation of signal transducer and activator of transcription 3 by interleukin-11 ameliorates cardiac fibrosis after myocardial infarction.

21 January 2018

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Association of Stat3 with HSF1 plays a critical role in G-CSF-induced cardio-protection against ischemia/reperfusion injury

21 January 2018

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Enhanced preservation of the rat heart after prolonged hypothermic ischemia with erythropoietin-supplemented Celsior solution

21 January 2018

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Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion

21 January 2018

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Cardioprotective function of mitochondrial-targeted and transcriptionally inactive STAT3 against ischemia and reperfusion injury

21 January 2018

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Mitochondrial calcium and the permeability transition in cell death

21 January 2018

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Toward a new STATe: the role of STATs in mitochondrial function

21 January 2018

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HDL protects against ischemia reperfusion injury by preserving mitochondrial integrity.

21 January 2018

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Acidosis, oxygen, and interference with mitochondrial permeability transition pore formation in the early minutes of reperfusion are critical to postconditioning's success

21 January 2018

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Inhibiting mitochondrial permeability transition pore opening: a new paradigm for myocardial preconditioning?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Leptin-induced cardioprotection involves JAK/STAT signaling that may be linked to the mitochondrial permeability transition pore

21 January 2018

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https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

The STAT3 inhibitor stattic impairs cardiomyocyte mitochondrial function through increased reactive oxygen species formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Function of mitochondrial Stat3 in cellular respiration

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Mitochondrial-targeted Signal transducer and activator of transcription 3 (STAT3) protects against ischemia-induced changes in the electron transport chain and the generation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

New role of JAK2/STAT3 signaling in endothelial cell oxidative stress injury and protective effect of melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Sex differences in endothelial STAT3 mediate sex differences in myocardial inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Thrombopoietin improved ventricular function and regulated remodeling genes in a rat model of myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Interleukin-10 deficiency impairs bone marrow-derived endothelial progenitor cell survival and function in ischemic myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Leptin stimulates ischemia-induced retinal neovascularization: possible role of vascular endothelial growth factor expressed in retinal endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Loss of STAT3 in mouse embryonic fibroblasts reveals its Janus-like actions on mitochondrial function and cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Loss of p27 upregulates MnSOD in a STAT3-dependent manner, disrupts intracellular redox activity and enhances cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Role of nuclear unphosphorylated STAT3 in angiotensin II type 1 receptor-induced cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

STAT3 regulates monocyte TNF-alpha production in systemic inflammation caused by cardiac surgery with cardiopulmonary bypass

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

IL-9 aggravates the development of atherosclerosis in ApoE-/- mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

IL-6 plays an obligatory role in late preconditioning via JAK-STAT signaling and upregulation of iNOS and COX-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Deletion of the innate immune NLRP3 receptor abolishes cardiac ischemic preconditioning and is associated with decreased Il-6/STAT3 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Innate defense mechanism against virus infection within the cardiac myocyte requiring gp130-STAT3 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Postconditioning inhibits myocardial apoptosis during prolonged reperfusion via a JAK2-STAT3-Bcl-2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Reduction of STAT3 expression induces mitochondrial dysfunction and autophagy in cardiac HL-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

STAT3 as a new autophagy regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

STAT3 deletion sensitizes cells to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Autophagy regulates TNFα-mediated joint destruction in experimental arthritis.

21 January 2018

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https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Autophagy fights disease through cellular self-digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

mTOR-STAT3-notch signalling contributes to ALDH2-induced protection against cardiac contractile dysfunction and autophagy under alcoholism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Swertiamarin attenuates inflammation mediators via modulating NF-κB/I κB and JAK2/STAT3 transcription factors in adjuvant induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

The NLRP3 inflammasome: a sensor for metabolic danger?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

STAT3 activity is necessary and sufficient for the development of immune-mediated myocarditis in mice and promotes progression to dilated cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Mechanisms of impaired regulation by CD4(+)CD25(+)FOXP3(+) regulatory T cells in human autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

The JAK2/STAT3 and mitochondrial pathways are essential for quercetin nanoliposome-induced C6 glioma cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Targeting mitochondrial STAT3 with the novel phospho-valproic acid (MDC-1112) inhibits pancreatic cancer growth in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Regulation of Mn-superoxide dismutase activity and neuroprotection by STAT3 in mice after cerebral ischemia

21 January 2018

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Regulatory systems for hypoxia-inducible gene expression in ischemic heart disease gene therapy

21 January 2018

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21 January 2018

Myocardial gene therapy

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Rebuilding the damaged heart: the potential of cytokines and growth factors in the treatment of ischemic heart disease

21 January 2018

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A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy.

21 January 2018

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https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Postinfarct treatment with oxytocin improves cardiac function and remodeling via activating cell-survival signals and angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Postinfarct active cardiac-targeted delivery of erythropoietin by liposomes with sialyl Lewis X repairs infarcted myocardium in rabbits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

gp130 plays a critical role in pressure overload-induced cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Importance of leptin signaling and signal transducer and activator of transcription-3 activation in mediating the cardiac hypertrophy associated with obesity

21 January 2018

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https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Cardiac-specific leptin receptor deletion exacerbates ischaemic heart failure in mice

21 January 2018

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https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Ethanolamine is a novel STAT-3 dependent cardioprotective agent

21 January 2018

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Ischaemic postconditioning protects against reperfusion injury via the SAFE pathway

21 January 2018

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https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

SDF-1/CXCR4 mediates acute protection of cardiac function through myocardial STAT3 signaling following global ischemia/reperfusion injury

21 January 2018

1 reference

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Effect of erythropoietin on exercise capacity in patients with moderate to severe chronic heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

The use of subcutaneous erythropoietin and intravenous iron for the treatment of the anemia of severe, resistant congestive heart failure improves cardiac and renal function and functional cardiac class, and markedly reduces hospitalizations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Erythropoietin protects the infant heart against ischemia-reperfusion injury by triggering multiple signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Resveratrol induces nuclear factor-κB activity in human cardiac cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Direct cardiac actions of erythropoietin (EPO): effects on cardiac contractility, BNP secretion and ischaemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Erythropoietin alleviates post-ischemic injury of rat hearts by attenuating nitrosative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Human thrombopoietin reduces myocardial infarct size, apoptosis, and stunning following ischaemia/reperfusion in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Effect of interleukin 6 deficiency on the expression of Bcl-2 and Bax in the murine heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Adipose stromal cells primed with hypoxia and inflammation enhance cardiomyocyte proliferation rate in vitro through STAT3 and Erk1/2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Neuroprotection by leptin in a rat model of permanent cerebral ischemia: effects on STAT3 phosphorylation in discrete cells of the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Leptin attenuates ischemia-reperfusion injury in the rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Leptin, the obesity-associated hormone, exhibits direct cardioprotective effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Obesity--a risk factor or a RISK factor for myocardial infarction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

High density lipoprotein/sphingosine-1-phosphate-induced cardioprotection: Role of STAT3 as part of the SAFE pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

The cardioprotective effects of urocortin are mediated via activation of the Src tyrosine kinase-STAT3 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Signal transducer and activator of transcription 3 is involved in the cardioprotective signalling pathway activated by insulin therapy at reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Vitamin C inhibits hypoxia-induced damage and apoptotic signaling pathways in cardiomyocytes and ischemic hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Carbon monoxide induces a late preconditioning-mimetic cardioprotective and antiapoptotic milieu in the myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Inhibition of soluble epoxide hydrolase preserves cardiomyocytes: role of STAT3 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

The red wine hypothesis: from concepts to protective signalling molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Melatonin in cardiovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Melatonin: the dawning of a treatment for fibrosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

The protective role of curcumin in cardiovascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Curcumin inhibits neuronal and vascular degeneration in retina after ischemia and reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

The effects of curcumin post-treatment against myocardial ischemia and reperfusion by activation of the JAK2/STAT3 signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

New role of Notch-mediated signaling pathway in myocardial ischemic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Remote ischemic conditioning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Regional ischemic 'preconditioning' protects remote virgin myocardium from subsequent sustained coronary occlusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Role of STAT3 in ischemic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Role of the JAK-STAT pathway in protection against myocardial ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Cardioprotective function of inducible nitric oxide synthase and role of nitric oxide in myocardial ischemia and preconditioning: an overview of a decade of research

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Modulation of apoptosis by nitric oxide: implications in myocardial ischemia and heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Postconditioning: a mechanical maneuver that triggers biological and molecular cardioprotective responses to reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Regulating RISK: a role for JAK-STAT signaling in postconditioning?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Cardioprotection by ischemic postconditioning is abolished in depressed rats: role of Akt and signal transducer and activator of transcription-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

The RIPOST-MI study, assessing remote ischemic perconditioning alone or in combination with local ischemic postconditioning in ST-segment elevation myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Multi-tasking: nuclear transcription factors with novel roles in the mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

Continuous Glycoprotein-130–Mediated Signal Transducer and Activator of Transcription-3 Activation Promotes Inflammation, Left Ventricular Rupture, and Adverse Outcome in Subacute Myocardial Infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

A murine model of inducible, cardiac-specific deletion of STAT3: Its use to determine the role of STAT3 in the upregulation of cardioprotective proteins by ischemic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14728222.2017.1275566

10.1080/14728222.2017.1275566

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28001439%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference