Critical role of the platelet-derived growth factor receptor (PDGFR) beta transmembrane domain in the TEL-PDGFRbeta cytosolic oncoprotein (Q39738130)

14 September 2017

Critical role of the platelet-derived growth factor receptor (PDGFR) beta transmembrane domain in the TEL-PDGFRbeta cytosolic oncoprotein (English)

1 reference

14 September 2017

transmembrane protein

0 references

author

Jean-Baptiste Demoulin

series ordinal

3

1 reference

14 September 2017

Federica Toffalini

1

1 reference

14 September 2017

Carina Hellberg

series ordinal

2

1 reference

14 September 2017

language of work or name

English

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publication date

17 February 2010

1 reference

14 September 2017

11

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

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14 September 2017

285

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14 September 2017

16

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14 September 2017

12268-12278

1 reference

describes a project that uses

14 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2852966/fullTextXML

inferred from PubMed Central ID database lookup

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Contacts between membrane proximal regions of the PDGF receptor ectodomain are required for receptor activation but not for receptor dimerization

14 September 2017

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Role of platelet-derived growth factors in physiology and medicine

14 September 2017

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Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor

14 September 2017

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14 September 2017

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Myeloproliferative disease induced by TEL-PDGFRB displays dynamic range sensitivity to Stat5 gene dosage.

14 September 2017

1 reference

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Activation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent

14 September 2017

1 reference

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Active conformation of the erythropoietin receptor: random and cysteine-scanning mutagenesis of the extracellular juxtamembrane and transmembrane domains

14 September 2017

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Oncogenic derivatives of platelet-derived growth factor receptors.

14 September 2017

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Site-selective regulation of platelet-derived growth factor beta receptor tyrosine phosphorylation by T-cell protein tyrosine phosphatase

14 September 2017

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The structural basis for autoinhibition of FLT3 by the juxtamembrane domain

14 September 2017

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Autoinhibition of the kit receptor tyrosine kinase by the cytosolic juxtamembrane region.

14 September 2017

1 reference

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Cell signaling by receptor tyrosine kinases

14 September 2017

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Rotational coupling of the transmembrane and kinase domains of the Neu receptor tyrosine kinase

14 September 2017

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Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

14 September 2017

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Fatal myeloproliferation, induced in mice by TEL/PDGFbetaR expression, depends on PDGFbetaR tyrosines 579/581

14 September 2017

1 reference

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A single amino acid substitution in a WW-like domain of diverse members of the PDGF receptor subfamily of tyrosine kinases causes constitutive receptor activation

14 September 2017

1 reference

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Identification of amino acids in the transmembrane and juxtamembrane domains of the platelet-derived growth factor receptor required for productive interaction with the bovine papillomavirus E5 protein

14 September 2017

1 reference

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The TEL gene products: nuclear phosphoproteins with DNA binding properties

14 September 2017

1 reference

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A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein

14 September 2017

1 reference

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The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways

14 September 2017

1 reference

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A single tyrosine of the interleukin-9 (IL-9) receptor is required for STAT activation, antiapoptotic activity, and growth regulation by IL-9

14 September 2017

1 reference

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Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852966

Three dimensional structure of the transmembrane region of the proto-oncogenic and oncogenic forms of the neu protein

14 September 2017

1 reference

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The fusion proteins TEL-PDGFRbeta and FIP1L1-PDGFRalpha escape ubiquitination and degradation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852966

Lack of evidence of stimulatory autoantibodies to platelet-derived growth factor receptor in patients with systemic sclerosis

14 September 2017

1 reference

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Tel/PDGFRbeta induces stem cell differentiation via the Ras/ERK and STAT5 signaling pathways

14 September 2017

1 reference

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JAK1 and Tyk2 activation by the homologous polycythemia vera JAK2 V617F mutation: cross-talk with IGF1 receptor.

14 September 2017

1 reference

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Active and inactive orientations of the transmembrane and cytosolic domains of the erythropoietin receptor dimer

14 September 2017

1 reference

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Molecular examination of the transmembrane requirements of the platelet-derived growth factor beta receptor for a productive interaction with the bovine papillomavirus E5 oncoprotein

14 September 2017

1 reference

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Definition of an inhibitory juxtamembrane WW-like domain in the platelet-derived growth factor beta receptor

25 September 2017

1 reference

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The TEL/PDGFbetaR fusion in chronic myelomonocytic leukemia signals through STAT5-dependent and STAT5-independent pathways.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852966

Strong oligomerization behavior of PDGFbeta receptor transmembrane domain and its regulation by the juxtamembrane regions

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852966

Activation of protein kinase C alpha is necessary for sorting the PDGF beta-receptor to Rab4a-dependent recycling

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852966

The transcription of FOXO genes is stimulated by FOXO3 and repressed by growth factors

15 June 2018

1 reference

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Transmembrane domain interactions control biological functions of neuropilin-1

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852966

Activation of Stat5 by platelet-derived growth factor (PDGF) is dependent on phosphorylation sites in PDGF beta-receptor juxtamembrane and kinase insert domains

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852966

Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and the PDGF beta-receptor

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852966

Ligand-Induced Homo-and Hetero-Dimerization of Platelet-Derived Growth Factor α- and β-Receptors in Intact Cells

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852966

Characterization of three new imatinib-responsive fusion genes in chronic myeloproliferative disorders generated by disruption of the platelet-derived growth factor receptor beta gene.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852966

The gene expression profile of PDGF-treated neural stem cells corresponds to partially differentiated neurons and glia

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852966

Platelet-derived growth factor stimulates membrane lipid synthesis through activation of phosphatidylinositol 3-kinase and sterol regulatory element-binding proteins

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852966

Autoinhibition of the platelet-derived growth factor beta-receptor tyrosine kinase by its C-terminal tail.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852966

Ligand-induced recruitment of Na+/H+-exchanger regulatory factor to the PDGF (platelet-derived growth factor) receptor regulates actin cytoskeleton reorganization by PDGF.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852966

The single transmembrane domains of ErbB receptors self-associate in cell membranes

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852966

Role of insulin receptor substrate-2 in interleukin-9-dependent proliferation

20 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M109.076638

Internal tandem duplication of the flt3 gene found in acute myeloid leukemia

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20164181

12 December 2020

inferred from PubMed ID database lookup

Characterization of the chronic myelomonocytic leukemia associated TEL-PDGF beta R fusion protein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20164181

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M109.076638

1 reference

14 September 2017

1 reference

14 September 2017

PubMed publication ID

20164181

1 reference