ISGylation - a key to lock the cell gates for preventing the spread of threats (Q40079195)

17 September 2017

ISGylation - a key to lock the cell gates for preventing the spread of threats (English)

1 reference

17 September 2017

Francisco Sánchez-Madrid

series ordinal

1

1 reference

PubMed ID

28842471

17 September 2017

Francisco Sánchez-Madrid

series ordinal

3

1 reference

17 September 2017

Susana Guerra

2

1 reference

PubMed ID

28842471

17 September 2017

language of work or name

English

0 references

publication date

25 August 2017

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17 September 2017

Journal of Cell Science

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17 September 2017

130

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17 September 2017

18

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17 September 2017

2961-2969

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Ubiquitination and phosphorylation of Beclin 1 and its binding partners: Tuning class III phosphatidylinositol 3-kinase activity and tumor suppression

17 September 2017

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Hepatitis C virus reveals a novel early control in acute immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Extracellular Vesicles Containing P301L Mutant Tau Accelerate Pathological Tau Phosphorylation and Oligomer Formation but Do Not Seed Mature Neurofibrillary Tangles in ALZ17 Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Structural basis of the specificity of USP18 toward ISG15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Mycobacterial disease and impaired IFN-γ immunity in humans with inherited ISG15 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISGylation governs the oncogenic function of Ki-Ras in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Free ISG15 triggers an antitumor immune response against breast cancer: a new perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Cell-Intrinsic Adaptation Arising from Chronic Ablation of a Key Rho GTPase Regulator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Up-regulation of interferon-stimulated gene15 and its conjugates by tumor necrosis factor-α via type I interferon-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISG15 predicts poor prognosis and promotes cancer stem cell phenotype in nasopharyngeal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Transcriptomic analysis of KSHV-infected primary oral fibroblasts: The role of interferon-induced genes in the latency of oncogenic virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISG15: A double edged sword in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Elevated expression of ISG15 in tumor cells interferes with the ubiquitin/26S proteasome pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISG15 as a novel tumor biomarker for drug sensitivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISG15 disrupts cytoskeletal architecture and promotes motility in human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISG15 deregulates autophagy in genotoxin-treated ataxia telangiectasia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Beyond ISGlylation: Functions of Free Intracellular and Extracellular ISG15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

IRF3 mediates a TLR3/TLR4-specific antiviral gene program

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

The ISG15 conjugation system broadly targets newly synthesized proteins: implications for the antiviral function of ISG15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Extracellular Vesicle-Associated Aβ Mediates Trans-Neuronal Bioenergetic and Ca2+-Handling Deficits in Alzheimer's Disease Models

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Identification and characterization of a novel ISG15-ubiquitin mixed chain and its role in regulating protein homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Type I IFN induces protein ISGylation to enhance cytokine expression and augments colonic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

UBE1L causes lung cancer growth suppression by targeting cyclin D1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

USP18 lack in microglia causes destructive interferonopathy of the mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Vaccinia virus E3 protein prevents the antiviral action of ISG15

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Stimulating the Release of Exosomes Increases the Intercellular Transfer of Prions

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Role for p53 in gene induction by double-stranded RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Herpes Simplex Virus and Interferon Signaling Induce Novel Autophagic Clusters in Sensory Neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Expression, regulation and function of the ISGylation system in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Consecutive Inhibition of ISG15 Expression and ISGylation by Cytomegalovirus Regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Reexamination of the role of ubiquitin-like modifier ISG15 in the phenotype of UBP43-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Mechanism of inhibition of retrovirus release from cells by interferon-induced gene ISG15

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Novel NEMO/IkappaB kinase and NF-kappa B target genes at the pre-B to immature B cell transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Interferon-stimulated gene 15 (ISG15) is a trigger for tumorigenesis and metastasis of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISG15 expression in response to double-stranded RNA or LPS in cultured Fetal bovine lung (FBL) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Transcriptome Sequencing to Identify Transcription Factor Regulatory Network and Alternative Splicing in Endothelial Cells Under VEGF Stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Telomere length regulates ISG15 expression in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISG15 modulates development of the erythroid lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Human USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TORCH syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Intercellular communication: diverse structures for exchange of genetic information

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Novel mode of ISG15-mediated protection against influenza A virus and Sendai virus in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Interferon-stimulated gene 15 (ISG15) and ISG15-linked proteins can associate with members of the selective autophagic process, histone deacetylase 6 (HDAC6) and SQSTM1/p62.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Increased cerebral protein ISGylation after focal ischemia is neuroprotective

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Nitrosylation of ISG15 prevents the disulfide bond-mediated dimerization of ISG15 and contributes to effective ISGylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Activation of double-stranded RNA-activated protein kinase (PKR) by interferon-stimulated gene 15 (ISG15) modification down-regulates protein translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISG15, an interferon-stimulated ubiquitin-like protein, is not essential for STAT1 signaling and responses against vesicular stomatitis and lymphocytic choriomeningitis virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Modification of PCNA by ISG15 plays a crucial role in termination of error-prone translesion DNA synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Positive feedback regulation of p53 transactivity by DNA damage-induced ISG15 modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

The interferon-induced gene ISG15 blocks retrovirus release from cells late in the budding process

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Involvement of UBE1L in ISG15 conjugation during retinoid-induced differentiation of acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

The role of extracellular vesicles in neurodegenerative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISG15 counteracts Listeria monocytogenes infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Extracellular vesicles: exosomes, microvesicles, and friends

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISG15 functions as an interferon-mediated antiviral effector early in the murine norovirus life cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Interferon-Stimulated Gene 15 Upregulation Precedes the Development of Blood-Brain Barrier Disruption and Cerebral Edema after Traumatic Brain Injury in Young Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Interferon-inducible antiviral effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISG15 is a critical microenvironmental factor for pancreatic cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Type I interferon imposes a TSG101/ISG15 checkpoint at the Golgi for glycoprotein trafficking during influenza virus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Type I interferons induce autophagy in certain human cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Positive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Emerging role of ISG15 in antiviral immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISG15 deficiency and increased viral resistance in humans but not mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISG15 modification of Ubc13 suppresses its ubiquitin-conjugating activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Ubiquitin-like Molecule ISG15 Acts as an Immune Adjuvant to Enhance Antigen-specific CD8 T-cell Tumor Immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISG15 is critical in the control of Chikungunya virus infection independent of UbE1L mediated conjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

The ubiquitin-like protein, ISG15, is a novel tumor-associated antigen for cancer immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Modification of BECN1 by ISG15 plays a crucial role in autophagy regulation by type I IFN/interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISG15 Regulates Peritoneal Macrophages Functionality against Viral Infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

A negative feedback of the HIF-1α pathway via interferon-stimulated gene 15 and ISGylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

ISG15 conjugation system targets the viral NS1 protein in influenza A virus-infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Influenza B virus non-structural protein 1 counteracts ISG15 antiviral activity by sequestering ISGylated viral proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.205468

Microtubule-associated protein 4 (MAP4) regulates assembly, protomer-polymer partitioning and synthesis of tubulin in cultured cells

21 January 2018

1 reference

12 December 2020

Protein tyrosine phosphatase CD148-mediated inhibition of T-cell receptor signal transduction is associated with reduced LAT and phospholipase Cgamma1 phosphorylation

1 reference

12 December 2020

Phosphorylation of MAP4 affects microtubule properties and cell cycle progression.

1 reference

12 December 2020

CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse

1 reference

12 December 2020

T-cell-antigen recognition and the immunological synapse

1 reference

12 December 2020

Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes.

1 reference

12 December 2020

HDAC6 deacetylase activity links the tubulin cytoskeleton with immune synapse organization

1 reference

12 December 2020

Calcium-calcineurin signaling in the regulation of cardiac hypertrophy

1 reference

12 December 2020

Engaged and bystander T cell receptors are down-modulated by different endocytotic pathways

1 reference

12 December 2020

Early phosphorylation kinetics of proteins involved in proximal TCR-mediated signaling pathways

1 reference

12 December 2020

MTOC translocation modulates IS formation and controls sustained T cell signaling

1 reference

12 December 2020

Shouts, whispers and the kiss of death: directional secretion in T cells

1 reference

12 December 2020

Localized diacylglycerol drives the polarization of the microtubule-organizing center in T cells

1 reference

12 December 2020

The polarity protein Par1b/EMK/MARK2 regulates T cell receptor-induced microtubule-organizing center polarization

1 reference

12 December 2020

The strength of T cell receptor signal controls the polarization of cytotoxic machinery to the immunological synapse

1 reference

12 December 2020

Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse

1 reference

12 December 2020

Integrin and CD3/TCR activation are regulated by the scaffold protein AKAP450.

1 reference

12 December 2020

T-cell signaling regulated by the Tec family kinase, Itk.

1 reference

12 December 2020

The LAT story: a tale of cooperativity, coordination, and choreography

1 reference

12 December 2020

Basis for MAP4 dephosphorylation-related microtubule network densification in pressure overload cardiac hypertrophy.

1 reference

12 December 2020

Imaging T-cell receptor activation reveals accumulation of tyrosine-phosphorylated CD3ζ in the endosomal compartment.

1 reference

12 December 2020

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

1 reference

12 December 2020

Dynein-Driven Transport of T Cell Receptor Microclusters Regulates Immune Synapse Formation and T Cell Activation

1 reference

12 December 2020

MAP4 and CLASP1 operate as a safety mechanism to maintain a stable spindle position in mitosis

1 reference

12 December 2020

γ-Tubulin 2 nucleates microtubules and is downregulated in mouse early embryogenesis.

1 reference

12 December 2020

End-binding protein 1 controls signal propagation from the T cell receptor

1 reference

12 December 2020

INF2 promotes the formation of detyrosinated microtubules necessary for centrosome reorientation in T cells

1 reference

12 December 2020

Septins 2, 7 and 9 and MAP4 colocalize along the axoneme in the primary cilium and control ciliary length

1 reference

12 December 2020

Orchestrating cytoskeleton and intracellular vesicle traffic to build functional immunological synapses.

1 reference

12 December 2020

Immune synapse: conductor of orchestrated organelle movement

1 reference

12 December 2020

A novel isoform of MAP4 organises the paraxial microtubule array required for muscle cell differentiation

1 reference

12 December 2020

HDAC6 regulates the dynamics of lytic granules in cytotoxic T lymphocytes

1 reference

12 December 2020

Aurora A drives early signalling and vesicle dynamics during T-cell activation

1 reference

12 December 2020

Analysis of MAP 4 function in living cells using green fluorescent protein (GFP) chimeras

1 reference

12 December 2020

Stabilization and functional modulation of microtubules by microtubule-associated protein 4.

1 reference

12 December 2020

Identifiers

DOI

10.1242/JCS.205468

1 reference

17 September 2017

1 reference

PubMed ID

28842471