Abl deregulates Cdk5 kinase activity and subcellular localization in Drosophila neurodegeneration (Q40239614)

18 September 2017

Abl deregulates Cdk5 kinase activity and subcellular localization in Drosophila neurodegeneration (English)

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18 September 2017

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H Lin

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18 September 2017

T-Y Lin

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2

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18 September 2017

J-L Juang

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3

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18 September 2017

25 August 2006

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Cell Death & Differentiation

18 September 2017

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18 September 2017

14

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18 September 2017

3

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18 September 2017

607-615

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4402033

18 September 2017

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cites work

Elevated neuronal Cdc2-like kinase activity in the Alzheimer disease brain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Cdk5 is a key factor in tau aggregation and tangle formation in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Alzheimer's disease. The tangled tale of tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Cycling, stressed-out and nervous: cellular functions of c-Abl

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Essential roles for the Abl and Arg tyrosine kinases in neurulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Regulation of cell death by the Abl tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Intracellular mechanisms of amyloid accumulation and pathogenesis in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Modelling neurodegenerative diseases in Drosophila: a fruitful approach?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Intraneuronal Abeta, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

A model for studying Alzheimer's Abeta42-induced toxicity in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Drosophila models of human neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Drosophila abelson interacting protein (dAbi) is a positive regulator of abelson tyrosine kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

The development of imatinib as a therapeutic agent for chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

The Drosophila Abelson proto-oncogene homolog: identification of mutant alleles that have pleiotropic effects late in development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

The cyclin-dependent kinase Cdk5 controls multiple aspects of axon patterning in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Neurotoxicity induces cleavage of p35 to p25 by calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Characterization of two recombinant Drosophila calpains. CALPA and a novel homolog, CALPB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Structure and regulation of the CDK5-p25(nck5a) complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Imatinib mesylate has limited activity against the central nervous system involvement of Philadelphia chromosome-positive acute lymphoblastic leukaemia due to poor penetration into cerebrospinal fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Gleevec inhibits β-amyloid production but not Notch cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

A Cdk5-p35 stable complex is involved in the beta-amyloid-induced deregulation of Cdk5 activity in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Cleavage of the cyclin-dependent kinase 5 activator p35 to p25 does not induce tau hyperphosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Cdk5-Mediated Inhibition of the Protective Effects of Transcription Factor MEF2 in Neurotoxicity-Induced Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Abi enhances Abl-mediated CDC2 phosphorylation and inactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Genetic Transformation of Drosophila with Transposable Element Vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Immunotherapy for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

7 January 2021

Drosophila abl and genetic redundancy in signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

7 January 2021

Induction of apoptosis in a Drosophila neuronal cell line by calcium ionophore

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

7 January 2021

Developmental regulation of the proteolysis of the p35 cyclin-dependent kinase 5 activator by phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

7 January 2021

Cyclin-dependent kinase 5 (CDK5) and neuronal cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

7 January 2021

enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402033

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4402033

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Dimensions Publication ID

18 September 2017

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