Do Memory CD4 T Cells Keep Their Cell-Type Programming: Plasticity versus Fate Commitment? Complexities of Interpretation due to the Heterogeneity of Memory CD4 T Cells, Including T Follicular Helper Cells (Q40241860)

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scientific article published on 21 April 2017

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English	Do Memory CD4 T Cells Keep Their Cell-Type Programming: Plasticity versus Fate Commitment? Complexities of Interpretation due to the Heterogeneity of Memory CD4 T Cells, Including T Follicular Helper Cells	scientific article published on 21 April 2017

Statements

scholarly article

1 reference

Europe PubMed Central

18 September 2017

Do Memory CD4 T Cells Keep Their Cell-Type Programming: Plasticity versus Fate Commitment? Complexities of Interpretation due to the Heterogeneity of Memory CD4 T Cells, Including T Follicular Helper Cells (English)

1 reference

Europe PubMed Central

18 September 2017

1 reference

based on heuristic

inferred from title

1

object named as

Shane Crotty

1 reference

Europe PubMed Central

18 September 2017

publication date

21 April 2017

1 reference

Europe PubMed Central

18 September 2017

Cold Spring Harbor Perspectives in Biology

1 reference

Europe PubMed Central

18 September 2017

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T follicular helper cell differentiation, function, and roles in disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional and epigenetic studies reveal multistep differentiation and plasticity of in vitro-generated and in vivo-derived follicular T helper cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Memory B cells contribute to rapid Bcl6 expression by memory follicular helper T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stability of the regulatory T cell lineage in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine-Independent Detection of Antigen-Specific Germinal Center T Follicular Helper Cells in Immunized Nonhuman Primates Using a Live Cell Activation-Induced Marker Technique

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping the Diversity of Follicular Helper T Cells in Human Blood and Tonsils Using High-Dimensional Mass Cytometry Analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Memory CD4 T cells emerge from effector T-cell progenitors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Th17 memory cells: live long and proliferate

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-21-Producing CD4(+) T Cells Promote Type 2 Immunity to House Dust Mites

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Codelivery of Envelope Protein in Alum with MVA Vaccine Induces CXCR3-Biased CXCR5+ and CXCR5- CD4 T Cell Responses in Rhesus Macaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150)

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Harnessing the plasticity of CD4(+) T cells to treat immune-mediated disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fate mapping of IL-17-producing T cells in inflammatory responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell immunity. Functional heterogeneity of human memory CD4⁺ T cell clones primed by pathogens or vaccines

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T Follicular Helper Cell Plasticity Shapes Pathogenic T Helper 2 Cell-Mediated Immunity to Inhaled House Dust Mite

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 1-1-1 fallacy

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of ICOS+CXCR3+CXCR5+ TH cells correlates with antibody responses to influenza vaccination

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The development and fate of follicular helper T cells defined by an IL-21 reporter mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Follicular helper CD4 T cells (TFH)

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Follicular Helper T Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl6 protein expression shapes pre-germinal center B cell dynamics and follicular helper T cell heterogeneity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Th17 cells are long lived and retain a stem cell-like molecular signature

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TFH cells progressively differentiate to regulate the germinal center response

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early Th1 cell differentiation is marked by a Tfh cell-like transition

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+ T Cells in Blood.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vaccine-induced th17 cells are maintained long-term postvaccination as a distinct and phenotypically stable memory subset

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulating Th1-Cell-type Tfh Cells that Exhibit Impaired B Cell Help Are Preferentially Activated during Acute Malaria in Children

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Definition of Human Epitopes Recognized in Tetanus Toxoid and Development of an Assay Strategy to Detect Ex Vivo Tetanus CD4+ T Cell Responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct memory CD4+ T cells with commitment to T follicular helper- and T helper 1-cell lineages are generated after acute viral infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-2-Dependent Allergen-Specific Tissue-Resident Memory Cells Drive Asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl6 expression specifies the T follicular helper cell program in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Most microbe-specific naïve CD4⁺ T cells produce memory cells during infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Th1 versus Th2 T cell polarization by whole-cell and acellular childhood pertussis vaccines persists upon re-immunization in adolescence and adulthood

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl6 expressing follicular helper CD4 T cells are fate committed early and have the capacity to form memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28432129

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1101/CSHPERSPECT.A032102

1 reference

Europe PubMed Central

18 September 2017

0 references

1 reference

Europe PubMed Central

18 September 2017

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