Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation (Q40331133)

19 September 2017

Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation (English)

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19 September 2017

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Meng Qiao

1

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19 September 2017

Paul Shapiro

2

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19 September 2017

Matthew Fosbrink

3

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19 September 2017

Horea Rus

4

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19 September 2017

Rakesh Kumar

5

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19 September 2017

Antonino Passaniti

6

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19 September 2017

language of work or name

English

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publication date

9 January 2006

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Journal of Biological Chemistry

19 September 2017

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19 September 2017

281

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19 September 2017

11

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19 September 2017

7118-7128

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The Runx genes: lineage-specific oncogenes and tumor suppressors

19 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M508162200

Role of RUNX family members in transcriptional repression and gene silencing

21 January 2018

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Oncogenic potential of the RUNX gene family: 'overview'.

21 January 2018

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Core-binding factors in hematopoiesis and immune function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Role of AML1/Runx1 in the pathogenesis of hematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Temporal and spatial parameters of skeletal gene expression: targeting RUNX factors and their coregulatory proteins to subnuclear domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Causal relationship between the loss of RUNX3 expression and gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Tumor suppressor activity of RUNX3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

The RUNX genes: gain or loss of function in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha

21 January 2018

1 reference

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Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): evidence for a new myc collaborating oncogene

21 January 2018

1 reference

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Regulation of human osteocalcin promoter in hormone-independent human prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Fidelity of Runx2 activity in breast cancer cells is required for the generation of metastases-associated osteolytic disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Coexpression of bone sialoprotein (BSP) and the pivotal transcriptional regulator of osteogenesis, Cbfa1/Runx2, in malignant melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Cell cycle regulators and hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

To cycle or not to cycle: a critical decision in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Regulation of cyclin-Cdk activity in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Cyclin/Cdk complexes: their involvement in cell cycle progression and mitotic division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Coordinate regulation of cell growth and differentiation by TGF-beta superfamily and Runx proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

RUNX transcription factors as key targets of TGF-beta superfamily signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Regulation of the osteoblast-specific transcription factor, Runx2: responsiveness to multiple signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Serine phosphorylation of RUNX2 with novel potential functions as negative regulatory mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Regulation of TGFbeta1-mediated growth inhibition and apoptosis by RUNX2 isoforms in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Mitotic kinases as regulators of cell division and its checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Cell cycle-regulated phosphorylation of p21-activated kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Nuclear envelope: torn apart at mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Pak1 phosphorylation on t212 affects microtubules in cells undergoing mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Targets of the cyclin-dependent kinase Cdk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Molecular mechanism of angiogenesis transcription factors and their therapeutic relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Transcriptional regulation of vascular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Runx transcription factors and the developmental balance between cell proliferation and differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

p107 and p130 Coordinately regulate proliferation, Cbfa1 expression, and hypertrophic differentiation during endochondral bone development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

TGF-beta signaling: positive and negative effects on tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Upstream and downstream targets of RUNX proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

The corepressor mSin3A regulates phosphorylation-induced activation, intranuclear location, and stability of AML1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Notch Signaling and ERK Activation Are Important for the Osteomimetic Properties of Prostate Cancer Bone Metastatic Cell Lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

Functional inactivation of a transcriptional corepressor by a signaling kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508162200

21 January 2018

Identifiers

DOI

10.1074/JBC.M508162200

1 reference

19 September 2017

1 reference