HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN&#160;expression (Q40656217)

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3 April 2020

title

HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN expression (English)

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Herpes simplex virus type 1

3 April 2020

main subject

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1 reference

12

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Juho Miettinen

3

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Stefanie Luecke

4

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Thaneas Prabakaran

5

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Line S Reinert

6

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Zhijian Chen

8

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Tuula A. Nyman

15

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Søren Riis Paludan

17

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author name string

Maria H Christensen

1

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Søren B Jensen

2

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David M Knipe

9

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Lynn W Enquist

11

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Trine H Mogensen

13

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Stephen A Rice

14

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Sampsa Matikainen

16

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Thomas Mettenleiter

7

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Rozanne M Sandri-Goldin

10

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language of work or name

English

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publication date

27 May 2016

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3 April 2020

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volume

35

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issue

13

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3 April 2020

page(s)

1385-1399

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describes a project that uses

3 April 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4931188/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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22 September 2017

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22 September 2017

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22 September 2017

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TLR3 deficiency in patients with herpes simplex encephalitis

22 September 2017

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22 September 2017

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ICP27 recruits Aly/REF but not TAP/NXF1 to herpes simplex virus type 1 transcription sites although TAP/NXF1 is required for ICP27 export

22 September 2017

1 reference

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Expression of herpes simplex virus ICP0 inhibits the induction of interferon-stimulated genes by viral infection

22 September 2017

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22 September 2017

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Herpes simplex virus triggers and then disarms a host antiviral response

22 September 2017

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Herpes simplex virus ICP0 mutants are hypersensitive to interferon

22 September 2017

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The RGG box motif of the herpes simplex virus ICP27 protein mediates an RNA-binding activity and determines in vivo methylation.

22 September 2017

1 reference

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Identification of nuclear and nucleolar localization signals in the herpes simplex virus regulatory protein ICP27.

22 September 2017

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Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27.

22 September 2017

1 reference

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The herpes simplex virus immediate-early protein ICP27 shuttles between nucleus and cytoplasm

22 September 2017

1 reference

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Role for herpes simplex virus 1 ICP27 in the inhibition of type I interferon signaling

25 September 2017

1 reference

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A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes

17 June 2018

1 reference

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Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection

17 June 2018

1 reference

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The viral ubiquitin ligase ICP0 is neither sufficient nor necessary for degradation of the cellular DNA sensor IFI16 during herpes simplex virus 1 infection.

19 August 2018

1 reference

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Alveolar macrophages are the primary interferon-alpha producer in pulmonary infection with RNA viruses.

19 August 2018

1 reference

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Induction of cytokine expression by herpes simplex virus in human monocyte-derived macrophages and dendritic cells is dependent on virus replication and is counteracted by ICP27 targeting NF-kappaB and IRF-3.

19 August 2018

1 reference

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The role of the UL41 gene of herpes simplex virus type 1 in evasion of non-specific host defence mechanisms during primary infection

19 August 2018

1 reference

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Splenic marginal metallophilic macrophages and marginal zone macrophages are the major interferon-alpha/beta producers in mice upon intravenous challenge with herpes simplex virus

19 August 2018

1 reference

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19 August 2018

Identifiers

DOI

10.15252/EMBJ.201593458

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27234299%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27234299%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

1 reference