Dimerization of presenilin-1 in vivo: suggestion of novel regulatory mechanisms leading to higher order complexes (Q40676340)

22 September 2017

Dimerization of presenilin-1 in vivo: suggestion of novel regulatory mechanisms leading to higher order complexes (English)

1 reference

22 September 2017

Sébastien S Hébert

1

1 reference

22 September 2017

Chantal Godin

2

1 reference

22 September 2017

Takami Tomiyama

3

1 reference

22 September 2017

Hiroshi Mori

4

1 reference

22 September 2017

Georges Lévesque

5

1 reference

22 September 2017

1 January 2003

1 reference

Biochemical and Biophysical Research Communications

22 September 2017

1 reference

22 September 2017

301

1 reference

22 September 2017

1

1 reference

22 September 2017

119-126

1 reference

Presenilins interact with armadillo proteins including neural-specific plakophilin-related protein and beta-catenin

22 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Presenilins and Alzheimer's disease: biological functions and pathogenic mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Aggresomes: a cellular response to misfolded proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Evidence for phosphorylation and oligomeric assembly of presenilin 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Expression of Alzheimer's disease-associated presenilin-1 is controlled by proteolytic degradation and complex formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Binding partners of Alzheimer's disease proteins: are they physiologically relevant?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

The transmembrane aspartates in presenilin 1 and 2 are obligatory for gamma-secretase activity and amyloid beta-protein generation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Missense mutation E318G of the presenilin-1 gene appears to be a nonpathogenic polymorphism.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Alzheimer's presenilin 1 gene expression in platelets and megakaryocytes. Identification of a novel splice variant

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

The presenilin genes: a new gene family involved in Alzheimer disease pathology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Endoproteolytic processing and stabilization of wild-type and mutant presenilin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

The biological and pathological function of the presenilin-1 Deltaexon 9 mutation is independent of its defect to undergo proteolytic processing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Presenilin 1 cleavage is a universal event in human organs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Amyloidogenic function of the Alzheimer's disease-associated presenilin 1 in the absence of endoproteolysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

G-protein-coupled receptors function as oligomers in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Dual roles of proteasome in the metabolism of presenilin 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Cell surface expression of the Alzheimer disease-related presenilin proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Detection of the presenilin 1 COOH-terminal fragment in the extracellular compartment: a release enhanced by apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Presenilin-1 immunoreactivity is localized intracellularly in Alzheimer's disease brain, but not detected in amyloid plaques

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Abnormal gel-electrophoretic behavior of presenilin 1 and it's fragment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Identification and characterization of presenilin I-467, I-463 and I-374.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Homodimerization of presenilin N-terminal fragments is affected by mutations linked to Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Evidence That Intramolecular Associations between Presenilin Domains Are Obligatory for Endoproteolytic Processing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Skeletal and CNS defects in Presenilin-1-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Mice lacking both presenilin genes exhibit early embryonic patterning defects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Presenilins as therapeutic targets for the treatment of Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

Cytoplasmic presenilin aggregates in proteasome inhibitor-treated cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902984-4

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-291X(02)02984-4

1 reference

22 September 2017

1 reference